2021
Rates of Reversal of Volume Overload in Hospitalized Acute Heart Failure: Association With Long-term Kidney Function
McCallum W, Tighiouart H, Testani JM, Griffin M, Konstam MA, Udelson JE, Sarnak MJ. Rates of Reversal of Volume Overload in Hospitalized Acute Heart Failure: Association With Long-term Kidney Function. American Journal Of Kidney Diseases 2021, 80: 65-78. PMID: 34843844, PMCID: PMC9135960, DOI: 10.1053/j.ajkd.2021.09.026.Peer-Reviewed Original ResearchConceptsB-type natriuretic peptideAcute heart failureEGFR declineHeart failureVolume overloadKidney functionNatriuretic peptideLower riskN-terminal pro-B-type natriuretic peptidePro-B-type natriuretic peptideHeart Failure Outcome StudyLong-term kidney functionG4-G5Adverse kidney outcomesClinical congestion scoreKidney function declineGlomerular filtration rateCause-specific hazards modelKidney outcomesTolvaptan (EVEREST) trialCardiovascular outcomesVasopressin AntagonismImproved survivalFunction declineDecreased risk
2020
Association of Volume Overload With Kidney Function Outcomes Among Patients With Heart Failure With Reduced Ejection Fraction
McCallum W, Tighiouart H, Testani JM, Griffin M, Konstam MA, Udelson JE, Sarnak MJ. Association of Volume Overload With Kidney Function Outcomes Among Patients With Heart Failure With Reduced Ejection Fraction. Kidney International Reports 2020, 5: 1661-1669. PMID: 33102958, PMCID: PMC7569703, DOI: 10.1016/j.ekir.2020.07.015.Peer-Reviewed Original ResearchB-type natriuretic peptideKidney function outcomesReduced ejection fractionVolume overloadCKD stageEGFR declineFunction outcomesNatriuretic peptideEjection fractionHeart failureCongestion scoreMultivariable modelN-terminal pro-B-type natriuretic peptidePro-B-type natriuretic peptideGlomerular filtration rate declineHeart Failure Outcome StudyMultivariable Cox regression modelsChronic kidney disease stageClinical congestion scoreElevated natriuretic peptidesJugular venous distensionLow NT-proBNPKidney disease stageCox regression modelTolvaptan (EVEREST) trial