Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function
Costello J, Dalkilic M, Beason S, Gehlhausen J, Patwardhan R, Middha S, Eads B, Andrews J. Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function. Genome Biology 2009, 10: r97. PMID: 19758432, PMCID: PMC2768986, DOI: 10.1186/gb-2009-10-9-r97.Peer-Reviewed Original ResearchConceptsDrosophila melanogasterGene networksGene functionExpression dataGene Ontology biological process annotationsHigh-throughput functional genomics dataEvidence of gene functionClusters of coregulated genesFunctional genomics dataNetwork of functional relationshipsMicroarray expression dataFunctional gene networksClasses of genesBiological process annotationsHigh-confidence networkProtein-protein interactionsGene expression dataUnannotated genesUncharacterized genesSequence similarityGenetic interactionsD. melanogasterMetazoan organismsGenomic dataProcess annotationsData-driven ontologies.
Costello J, Schrider D, Gehlhausen J, Dalkilic M. Data-driven ontologies. Biocomputing 2009, 15-26. PMID: 19213131.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsComputational BiologyData Interpretation, StatisticalGene Regulatory NetworksGenes, FungalModels, GeneticOligonucleotide Array Sequence AnalysisSaccharomyces cerevisiae