2006
Estrogen Receptor-Mediated Rapid Signaling
Moriarty K, Kim KH, Bender JR. Estrogen Receptor-Mediated Rapid Signaling. Endocrinology 2006, 147: 5557-5563. PMID: 16946015, DOI: 10.1210/en.2006-0729.Peer-Reviewed Original ResearchConceptsMembrane estrogen receptorsPlasma membrane-associated formSplice variantsMembrane-associated formTranscriptional activationMultimolecular complexesRapid signalingSignaling cascadesMolecular componentsSpecific tissuesER splice variantsMolecular levelSpecific fashionEnzymatic pathwaysEstrogen receptorEstrogen responseNuclear responsePathwayPhysiological outcomesReceptorsComplexesSignalingVariantsVascular endotheliumRapid response
2003
Estrogen-Stimulated, Membrane-Initiated Receptor-Ligand Interactions in Vascular Cells
Lei L, Haynes M, Bender J. Estrogen-Stimulated, Membrane-Initiated Receptor-Ligand Interactions in Vascular Cells. 2003, 37-45. DOI: 10.1007/978-1-4615-0339-2_5.Peer-Reviewed Original ResearchEndothelial nitric oxide synthaseNitric oxideEndothelial cellsNitric oxide synthaseMembrane estrogen receptorsVascular endothelial cellsEndothelial dysfunctionOxide synthaseEstrogen receptorChronic activationVascular endotheliumLuminal liningPathology 1Vascular cellsMental healthBlood vesselsProtective actionHomeostatic stateReceptorsPivotal rolePertinent chaptersVast majorityCellsDysfunctionReversible phase
1999
Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis
Russell K, Stern D, Polverini P, Bender J. Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis. American Journal Of Physiology 1999, 277: h2205-h2211. PMID: 10600838, DOI: 10.1152/ajpheart.1999.277.6.h2205.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCells, CulturedCorneaEndothelial Growth FactorsEndothelium, VascularErbB ReceptorsHumansLymphokinesMiceNeovascularization, PhysiologicNeuregulinsRatsReceptor, ErbB-2Receptor, ErbB-3Receptor, ErbB-4ThrombinUmbilical VeinsVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsConceptsHuman umbilical vein endothelial cellsVascular endotheliumErbB receptorsReceptor tyrosine phosphorylationStimulation of HUVECsRapid calcium fluxReceptor family membersEndothelial cell growth factorTransmembrane tyrosine kinase receptorVascular endothelial cell growth factorEndothelial cell signalingReceptor-ligand interactionsTyrosine kinase receptorsEpidermal growth factor receptorVascular endothelial growthCell growth factorUmbilical vein endothelial cellsCell signalingGrowth factor receptorTyrosine phosphorylationVivo angiogenic responseExpression patternsGrowth regulationVein endothelial cellsIntracellular signaling
1993
Initiation of cardiac allograft rejection New developments in cellular and molecular mechanisms
Pfau S, Bender J. Initiation of cardiac allograft rejection New developments in cellular and molecular mechanisms. Trends In Cardiovascular Medicine 1993, 3: 196-203. PMID: 21244933, DOI: 10.1016/1050-1738(93)90006-r.Peer-Reviewed Original ResearchT cell activationEnd-stage heart diseaseEffective immunosuppressive therapyNatural killer lymphocytesImmune effector cellsViable therapeutic optionT lymphocyte recognitionT cell biologyEarly eventsCardiac transplantationImmunosuppressive therapyMedical complicationsEffector cellsTherapeutic optionsCytokine productionInflammatory cellsHeart diseaseKiller lymphocytesForeign antigensT cellsImmune responseClinical utilityVascular endotheliumRejection processLong-term success