2020
Posttraumatic Stress Disorder, Antidepressant Use, and Hemorrhagic Stroke in Young Men and Women
Gaffey AE, Rosman L, Burg MM, Haskell SG, Brandt CA, Skanderson M, Dziura J, Sico JJ. Posttraumatic Stress Disorder, Antidepressant Use, and Hemorrhagic Stroke in Young Men and Women. Stroke 2020, 52: 121-129. PMID: 33297868, PMCID: PMC7770089, DOI: 10.1161/strokeaha.120.030379.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderHemorrhagic strokeHealth care utilizationUse of SSRIsGreater riskSSRI useStroke riskCare utilizationStress disorderEffects of PTSDIncident hemorrhagic strokeMiddle-aged veteransModifiable risk factorsNon-pharmacological treatmentMultivariate Cox modelNorepinephrine reuptake inhibitorsOverall incidence rateHemorrhagic stroke riskSNRI useIncident strokeAntidepressant useReuptake inhibitorsComorbid conditionsLifestyle factorsPsychiatric comorbidity
2019
Posttraumatic Stress Disorder and Risk for Stroke in Young and Middle-Aged Adults
Rosman L, Sico JJ, Lampert R, Gaffey AE, Ramsey CM, Dziura J, Chui PW, Cavanagh CE, Brandt C, Haskell S, Burg MM. Posttraumatic Stress Disorder and Risk for Stroke in Young and Middle-Aged Adults. Stroke 2019, 50: 2996-3003. PMID: 31619151, DOI: 10.1161/strokeaha.119.026854.Peer-Reviewed Original ResearchConceptsTransient ischemic attackIncident transient ischemic attackPosttraumatic stress disorderEffects of PTSDIschemic strokeIncident strokeHealthcare utilizationIncidence of TIAStress disorderYoung adultsMiddle-aged veteransStroke risk factorsMultivariate Cox modelIschemic stroke riskAge-specific prevention strategiesVeterans Health AdministrationMiddle-aged adultsIschemic attackStroke riskPsychological factorsUnadjusted analysesRisk factorsEffect modificationCox modelPsychiatric disorders
2018
Survey Analysis of the Use, Effectiveness, and Patient‐Reported Tolerability of Inhaled Oxygen Compared With Injectable Sumatriptan for the Acute Treatment of Cluster Headache
Schindler EAD, Wright DA, Weil MJ, Gottschalk CH, Pittman BP, Sico JJ. Survey Analysis of the Use, Effectiveness, and Patient‐Reported Tolerability of Inhaled Oxygen Compared With Injectable Sumatriptan for the Acute Treatment of Cluster Headache. Headache The Journal Of Head And Face Pain 2018, 58: 1568-1578. PMID: 30221765, DOI: 10.1111/head.13405.Peer-Reviewed Original ResearchConceptsInjectable sumatriptanCluster headacheAcute treatmentMedication responseOxygen deliverySide effectsPatient-reported side effectsSecondary analysisTherapeutic response rateCigarette smoking historyOptimization of therapyOptimal oxygen deliveryPositive predictorSmoking historyOxygen therapyCigarette smokingHeadache clinicTherapeutic optionsPatient populationPharmacologic interventionsTriptan medicationsComparable efficacyDaily attacksMale genderTherapeutic response
2016
Have clinicians adopted the use of brain MRI for patients with TIA and minor stroke?
Chaturvedi S, Ofner S, Baye F, Myers LJ, Phipps M, Sico JJ, Damush T, Miech E, Reeves M, Johanning J, Williams LS, Arling G, Cheng E, Yu Z, Bravata D. Have clinicians adopted the use of brain MRI for patients with TIA and minor stroke? Neurology 2016, 88: 237-244. PMID: 27927939, PMCID: PMC5272790, DOI: 10.1212/wnl.0000000000003503.Peer-Reviewed Original ResearchConceptsTIA/minor strokeDays of presentationMinor strokeDiffusion-weighted imagingPrevious guidelinesHospital complexityCoronary artery diseaseMinor stroke patientsVeterans Affairs hospitalPreferred imaging modalityUse of MRISubset of hospitalsFacility-level variablesPerformance of MRINational Health SystemPrior strokeSymptom durationChart abstractionArtery diseaseBlood pressureHeart failureNeurologic consultationStroke patientsAtrial fibrillationClinical variables
2011
Anemia is Associated with Poor Outcomes in Patients with Less Severe Ischemic Stroke
Sico JJ, Concato J, Wells CK, Lo AC, Nadeau SE, Williams LS, Peixoto AJ, Gorman M, Boice JL, Bravata DM. Anemia is Associated with Poor Outcomes in Patients with Less Severe Ischemic Stroke. Journal Of Stroke And Cerebrovascular Diseases 2011, 22: 271-278. PMID: 22100828, DOI: 10.1016/j.jstrokecerebrovasdis.2011.09.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnemiaBrain IschemiaChi-Square DistributionDisability EvaluationFemaleHospice CareHospital MortalityHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient AdmissionPatient DischargePredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexStrokeUnited StatesYoung AdultConceptsAcute ischemic strokeSevere ischemic strokeSevere strokeHospital mortalityIschemic strokeConsecutive ischemic stroke patientsHealth Stroke Scale scoreAdmission National InstitutesRole of anemiaStroke Scale scoreChronic kidney diseaseIschemic stroke patientsCongestive heart failureAcute myocardial infarctionAdmission anemiaCombined endpointRetrospective cohortStroke severitySymptom onsetHeart failureHospital admissionStroke patientsPoor outcomeKidney diseaseMyocardial infarction