2020
Clinical factors associated with acute exacerbations of chronic rhinosinusitis
Kwah JH, Somani SN, Stevens WW, Kern RC, Smith SS, Welch KC, Conley DB, Tan BK, Grammer LC, Yang A, Schleimer RP, Peters AT. Clinical factors associated with acute exacerbations of chronic rhinosinusitis. Journal Of Allergy And Clinical Immunology 2020, 145: 1598-1605. PMID: 32004523, PMCID: PMC8177481, DOI: 10.1016/j.jaci.2020.01.023.Peer-Reviewed Original ResearchConceptsFrequent acute exacerbationsChronic rhinosinusitisAcute exacerbationAllergic rhinitisClinical factorsEosinophil countAutoimmune diseasesSignificant health care burdenSinus disease severityRetrospective cohort studySystemic corticosteroid useHealth care burdenHigh-risk phenotypeAntibiotic allergyExacerbation frequencyFrequent exacerbationsSinus symptomsCorticosteroid useCohort studyLower FEVNasal polyposisAntibody deficiencyImpaired qualityImmunologic diseasesOdds ratio
2019
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT. Nasal polyps and rhinosinusitis. Allergy & Asthma Proceedings 2019, 40: 380-384. PMID: 31690375, DOI: 10.2500/aap.2019.40.4252.Peer-Reviewed Original ResearchConceptsAspirin-exacerbated respiratory diseaseChronic rhinosinusitisNasal polypsNasal congestionEthmoid sinusSinus cavityCiliated columnar epithelial cellsPolyp sizeAcute sinus infectionsTopical nasal steroidsAnterior ethmoid sinusChronic mucosal inflammationAllergic fungal rhinosinusitisMajority of patientsTreatment of choiceParanasal sinus mucosaPosterior ethmoid sinusColumnar epithelial cellsAspirin desensitizationIntranasal corticosteroidsNasal steroidsOral steroidsAcute rhinosinusitisMaintenance therapyPersistent asthma