2020
Clinical factors associated with acute exacerbations of chronic rhinosinusitis
Kwah JH, Somani SN, Stevens WW, Kern RC, Smith SS, Welch KC, Conley DB, Tan BK, Grammer LC, Yang A, Schleimer RP, Peters AT. Clinical factors associated with acute exacerbations of chronic rhinosinusitis. Journal Of Allergy And Clinical Immunology 2020, 145: 1598-1605. PMID: 32004523, PMCID: PMC8177481, DOI: 10.1016/j.jaci.2020.01.023.Peer-Reviewed Original ResearchConceptsFrequent acute exacerbationsChronic rhinosinusitisAcute exacerbationAllergic rhinitisClinical factorsEosinophil countAutoimmune diseasesSignificant health care burdenSinus disease severityRetrospective cohort studySystemic corticosteroid useHealth care burdenHigh-risk phenotypeAntibiotic allergyExacerbation frequencyFrequent exacerbationsSinus symptomsCorticosteroid useCohort studyLower FEVNasal polyposisAntibody deficiencyImpaired qualityImmunologic diseasesOdds ratio
2019
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT. Nasal polyps and rhinosinusitis. Allergy & Asthma Proceedings 2019, 40: 380-384. PMID: 31690375, DOI: 10.2500/aap.2019.40.4252.Peer-Reviewed Original ResearchMeSH KeywordsAdrenal Cortex HormonesAnti-Bacterial AgentsBacterial InfectionsChronic DiseaseHumansNasal PolypsRhinitisSinusitisConceptsAspirin-exacerbated respiratory diseaseChronic rhinosinusitisNasal polypsNasal congestionEthmoid sinusSinus cavityCiliated columnar epithelial cellsPolyp sizeAcute sinus infectionsTopical nasal steroidsAnterior ethmoid sinusChronic mucosal inflammationAllergic fungal rhinosinusitisMajority of patientsTreatment of choiceParanasal sinus mucosaPosterior ethmoid sinusColumnar epithelial cellsAspirin desensitizationIntranasal corticosteroidsNasal steroidsOral steroidsAcute rhinosinusitisMaintenance therapyPersistent asthmaPrevalence and characterization of chronic rhinosinusitis in patients with non‒cystic fibrosis bronchiectasis at a tertiary care center in the United States
Somani SN, Kwah JH, Yeh C, Conley DB, Grammer LC, Kern RC, Prickett M, Schleimer RP, Smith SS, Stevens WW, Tan BK, Welch KC, Peters AT. Prevalence and characterization of chronic rhinosinusitis in patients with non‒cystic fibrosis bronchiectasis at a tertiary care center in the United States. International Forum Of Allergy & Rhinology 2019, 9: 1424-1429. PMID: 31589811, PMCID: PMC6913921, DOI: 10.1002/alr.22436.Peer-Reviewed Original ResearchConceptsPresence of CRSTertiary care centerChronic rhinosinusitisCare centerNon-cystic fibrosis bronchiectasisPrevalence of CRSConcomitant chronic rhinosinusitisRetrospective cohort studyGastroesophageal reflux diseasePeripheral eosinophil countPulmonary function testingTertiary medical centerNumerous comorbid conditionsTreatment of patientsUnited States populationBronchiectasis patientsFibrosis bronchiectasisReflux diseaseAllergic rhinitisCohort studyRadiographic evidenceAntibody deficiencyComorbid conditionsEosinophil countFunction testing