Featured Publications
Children of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight
Lydecker JA, Grilo CM. Children of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight. International Journal Of Eating Disorders 2016, 50: 648-656. PMID: 27859458, PMCID: PMC5429220, DOI: 10.1002/eat.22648.Peer-Reviewed Original ResearchConceptsBinge-eating disorderChild weightChildren's bingeEating-disorder psychopathologyHigher child weightCross-sectional findingsChild overweightProspective confirmationChildren's eatingChild feedingChild overeatingDietary restrictionObesityClinical interventionsPrevention effortsEating Disorder BehaviorsDisordersBingePreliminary evidencePotential factorsEatingCurrent studyLimited literatureCore featuresOBCognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial
Grilo C, Lydecker J, Gueorguieva R. Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial. International Journal Of Eating Disorders 2023, 56: 1544-1553. PMID: 37144325, PMCID: PMC10524840, DOI: 10.1002/eat.23975.Peer-Reviewed Original ResearchConceptsInitial acute treatmentBinge-eating disorderCognitive behavioral therapyAcute treatmentBinge-eating frequencyInitial interventionTherapist-led cognitive behavioural therapyInitial pharmacological treatmentTreat remission ratesEvidence-based treatmentsSingle-site trialAcute efficacyRemission rateAdult patientsInitial treatmentPharmacological treatmentPatientsPosttreatment assessmentBehavioral treatmentSufficient benefitTherapyDisordersInterventionTreatmentPharmacotherapy
2023
The Relationship of Self-identified Weight Status With Perceived Mental and Physical Health
Hamilton A, Smith S, Lydecker J. The Relationship of Self-identified Weight Status With Perceived Mental and Physical Health. Journal Of Psychiatric Practice 2023, 29: 430-438. PMID: 37948168, PMCID: PMC10653675, DOI: 10.1097/pra.0000000000000744.Peer-Reviewed Original ResearchMeSH KeywordsBinge-Eating DisorderFeeding and Eating DisordersHumansObesityOverweightPsychopathologyConceptsOW/OBBinge-eating disorderDisorder psychopathologyPhysical healthMental healthStudy groupBulimia nervosaOW/OB groupBN groupOverweight/obesityFuture clinical researchOB groupWeight statusObesityClinical researchBED groupOverweightDepressionHealthPsychopathologyDisordersGroupOBLow levelsAnalysis of varianceNaltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reductionNaltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial
Grilo C, Lydecker J, Gueorguieva R. Naltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2023, 53: 7775-7784. PMID: 37366017, PMCID: PMC10751383, DOI: 10.1017/s0033291723001800.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderBinge-eating remissionAcute treatmentMaintenance treatmentBinge-eating frequencyDouble-blind placebo-controlled trialBehavioral weight loss therapyWeight lossCo-occurring obesitySuccessful acute treatmentPlacebo-controlled trialWeight loss therapySignificant additional weight lossSingle-site trialAdditional weight lossAcute efficacyRemission rateAdult patientsComorbid obesityBupropionInitial interventionPosttreatment assessmentRespondersPlacebo
2022
Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial
Grilo CM, Lydecker JA, Fineberg SK, Moreno JO, Ivezaj V, Gueorguieva R. Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial. American Journal Of Psychiatry 2022, 179: 927-937. PMID: 36285406, PMCID: PMC9722598, DOI: 10.1176/appi.ajp.20220267.Peer-Reviewed Original ResearchConceptsBehavioral weight loss therapyBinge-eating disorderPlacebo groupBupropion groupWeight lossRandomized double-blind placebo-controlled trialDouble-blind placebo-controlled trialLogistic regressionBinge-eating remissionPlacebo-controlled trialWeight loss therapyDouble-blind placeboSerious public health problemPublic health problemEvidence-based treatmentsRate of participantsBinge-eating frequencyBinge Eating DisorderMedical comorbiditiesRemission rateLoss therapyPercent weight lossMixed modelsFunctional impairmentSecondary measures
2021
Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder
Grilo CM, Kerrigan SG, Lydecker JA, White MA. Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder. Obesity 2021, 29: 2026-2034. PMID: 34582624, PMCID: PMC8612949, DOI: 10.1002/oby.23278.Peer-Reviewed Original ResearchConceptsBehavioral weight loss treatmentWeight loss treatmentLatinx patientsPhysical activity changesBWL treatmentReduced depressionCommunity mental health centerWeight lossPA changePlacebo-controlled trialAddition of orlistatMental health centersActivity changesPrognostic significanceMedication conditionHealth centersLoss treatmentPatientsObesitySecondary analysisClinical settingBed statusBaselineTreatmentDepression
2020
Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study
Grilo CM, Lydecker JA, Morgan PT, Gueorguieva R. Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study. Clinical Therapeutics 2020, 43: 112-122.e1. PMID: 33218742, PMCID: PMC7902424, DOI: 10.1016/j.clinthera.2020.10.010.Peer-Reviewed Original ResearchConceptsBinge-eating disorderEating-disorder psychopathologyPilot RCTTreatment of BEDOutcome time pointDouble-blind treatmentPercentage of patientsControlled Pilot StudyDiscontinuation of medicationTreatment of bingeEvidence-based treatmentsBinge-eating frequencyBupropion combinationAdult patientsAdverse eventsComorbid obesitySecondary outcomesPrimary outcomeAcute effectsFunctional impairmentPlaceboLong-term effectsPatientsMost outcomesObesityLanguage Matters: Patients’ Preferred Terms for Discussing Obesity and Disordered Eating with Health Care Providers After Bariatric Surgery
Ivezaj V, Lydecker JA, Grilo CM. Language Matters: Patients’ Preferred Terms for Discussing Obesity and Disordered Eating with Health Care Providers After Bariatric Surgery. Obesity 2020, 28: 1412-1418. PMID: 32662251, PMCID: PMC7501175, DOI: 10.1002/oby.22868.Peer-Reviewed Original ResearchConceptsHealth care providersBariatric surgeryCare providersCross-sectional studyPatient-centered carePreferred termHealth care systemTreatment trialsPatient preferencesSurgeryBehavioral treatmentControl eatingLanguage preferenceCare systemRacial differencesObesityPatientsWeight biasProvidersBMIWeightIndividualsControlTrialsCare
2019
Getting a head start: identifying pretreatment correlates associated with early weight loss for individuals participating in weight loss treatment
Wiedemann AA, Baumgardt SS, Ivezaj V, Kerrigan SG, Lydecker JA, Grilo CM, Barnes RD. Getting a head start: identifying pretreatment correlates associated with early weight loss for individuals participating in weight loss treatment. Translational Behavioral Medicine 2019, 11: 236-243. PMID: 31816053, PMCID: PMC7877303, DOI: 10.1093/tbm/ibz149.Peer-Reviewed Original ResearchConceptsEarly weight lossWeight loss treatmentUsual careWeight lossLow pretreatmentDepressive symptomsWeek sixMeaningful weight lossPrimary care settingBinge-eating disorder diagnosisEating Disorder Examination interviewGreater weight lossNutrition psychoeducationTreatment cessationPercent weight lossPrimary careNPC groupObesity rangeLoss treatmentEmotional overeatingExamination interviewDisorder diagnosisPretreatment correlatesMotivational interviewingTreatmentToward an understanding of the distinctiveness of body-image constructs in persons categorized with overweight/obesity, bulimia nervosa, and binge-eating disorder
Grilo CM, Ivezaj V, Lydecker JA, White MA. Toward an understanding of the distinctiveness of body-image constructs in persons categorized with overweight/obesity, bulimia nervosa, and binge-eating disorder. Journal Of Psychosomatic Research 2019, 126: 109757. PMID: 31522010, PMCID: PMC6842703, DOI: 10.1016/j.jpsychores.2019.109757.Peer-Reviewed Original ResearchConceptsBinge-eating disorderOverweight/obesityStudy groupBulimia nervosaClinical measuresWeight/shapeWeight disordersEating-disorder psychopathologyBody image disturbanceStrength of associationClinical manifestationsObesityWeight gainCommunity volunteersDisordersBody image constructsNervosaDepressionTreatment formulationGroupExamining physical activity and correlates in adults with healthy weight, overweight/obesity, or binge‐eating disorder
Carr MM, Lydecker JA, White MA, Grilo CM. Examining physical activity and correlates in adults with healthy weight, overweight/obesity, or binge‐eating disorder. International Journal Of Eating Disorders 2019, 52: 159-165. PMID: 30690763, PMCID: PMC6396689, DOI: 10.1002/eat.23003.Peer-Reviewed Original ResearchConceptsOW/OBBinge-eating disorderSelf-reported physical activityOverweight/obesityPhysical activityHealthy weightOW/OB groupBED groupPhysical healthStrong associationSelf-reported physical healthSubgroup of adultsImportant treatment targetWeekly boutsPhysical inactivityOB groupStudy groupTreatment targetsWhite womenActive individualsMost participantsObesityHigh rateHealthBinge
2018
Associations of parents' self, child, and other “fat talk” with child eating behaviors and weight
Lydecker JA, Riley KE, Grilo CM. Associations of parents' self, child, and other “fat talk” with child eating behaviors and weight. International Journal Of Eating Disorders 2018, 51: 527-534. PMID: 29542177, PMCID: PMC6002914, DOI: 10.1002/eat.22858.Peer-Reviewed Original ResearchConceptsFat talkParents of preadolescentsParents' selfChildren's eatingChild sexSecretive eatingNegative communicationWeight-related interventionsFront of childrenAdolescent girlsPeer groupEatingPreadolescentsParentsSelfAdolescentsChildrenDifferent formsTalkWeight variablesBehaviorOverweight/obesityAssociationGirlsIntervention
2017
Characteristics of Weight Loss Trajectories in a Comprehensive Lifestyle Intervention
Marek RJ, Coulon SM, Brown JD, Lydecker JA, Marek S, Malcolm R, O'Neil PM. Characteristics of Weight Loss Trajectories in a Comprehensive Lifestyle Intervention. Obesity 2017, 25: 2062-2067. PMID: 29086487, DOI: 10.1002/oby.21942.Peer-Reviewed Original ResearchConceptsWeight loss trajectoriesAverage weight lossWeight lossLifestyle interventionWeight changeWeight gainComprehensive lifestyle interventionLatent class analysisMeal replacement dietMore tailored interventionsLifestyle change counselingWeekly weight changesWeekly weight gainPercent weight lossLess optimal outcomesLifestyle programEfficacy dataGroup 2Group 1Group 3Class analysisPatientsTailored interventionsOptimal outcomesPercent weight gain“I only watch for the commercials”: Messages about weight, eating and race in Super Bowl advertisements
Lydecker JA, Izzo A, Spielberger G, Grilo CM. “I only watch for the commercials”: Messages about weight, eating and race in Super Bowl advertisements. International Journal Of Clinical Practice 2017, 71: e13026. PMID: 28941009, PMCID: PMC5728649, DOI: 10.1111/ijcp.13026.Peer-Reviewed Original ResearchRumination in Patients with Binge‐Eating Disorder and Obesity: Associations with Eating‐Disorder Psychopathology and Weight‐bias Internalization
Wang SB, Lydecker JA, Grilo CM. Rumination in Patients with Binge‐Eating Disorder and Obesity: Associations with Eating‐Disorder Psychopathology and Weight‐bias Internalization. European Eating Disorders Review 2017, 25: 98-103. PMID: 28078784, PMCID: PMC5318238, DOI: 10.1002/erv.2499.Peer-Reviewed Original ResearchConceptsShape/weightWeight bias internalizationEating-disorder psychopathologyBinge-eating disorderCognitive processesGreater eating-disorder psychopathologyImportant cognitive processesOvervaluation of shapeGreater weight bias internalizationHierarchical multiple regressionTreatment-seeking patientsGreater ruminationRuminationDiscrimination experiencesPhysical healthPsychopathologyNegative attitudesMultiple regressionOvervaluationObesity treatmentComorbid obesityAttitudesDisordersExperienceFindings
2016
Preferred descriptions for loss of control while eating and weight among patients with binge eating disorder
Roberto CA, Galbraith K, Lydecker JA, Ivezaj V, Barnes RD, White MA, Grilo CM. Preferred descriptions for loss of control while eating and weight among patients with binge eating disorder. Psychiatry Research 2016, 246: 548-553. PMID: 27821368, PMCID: PMC5161684, DOI: 10.1016/j.psychres.2016.09.045.Peer-Reviewed Original ResearchWords will never hurt me? Preferred terms for describing obesity and binge eating
Lydecker JA, Galbraith K, Ivezaj V, White MA, Barnes RD, Roberto CA, Grilo CM. Words will never hurt me? Preferred terms for describing obesity and binge eating. International Journal Of Clinical Practice 2016, 70: 682-690. PMID: 27354290, PMCID: PMC4965320, DOI: 10.1111/ijcp.12835.Peer-Reviewed Original ResearchThe apple of their eye: Attitudinal and behavioral correlates of parents’ perceptions of child obesity
Lydecker JA, Grilo CM. The apple of their eye: Attitudinal and behavioral correlates of parents’ perceptions of child obesity. Obesity 2016, 24: 1124-1131. PMID: 26916369, PMCID: PMC4846571, DOI: 10.1002/oby.21439.Peer-Reviewed Original ResearchConceptsAttitudes/behaviorsWeight-related attitudesParents' specific needsOverweight/obesityOnline measuresCommunity sampleParental practicesBehavioral correlatesParents' perceptionsParents' responsesChildren's eatingParental perceptionsChild overweight/obesityActual childrenTreatment programPerceptionChild weightParentsEatingSpecific needsChildrenCorrelatesChildren 5Dual needsFurther research
2015
Biopsychosocial Correlates of Binge Eating Disorder in Caucasian and African American Women with Obesity in Primary Care Settings
Udo T, White MA, Lydecker JL, Barnes RD, Genao I, Garcia R, Masheb RM, Grilo CM. Biopsychosocial Correlates of Binge Eating Disorder in Caucasian and African American Women with Obesity in Primary Care Settings. European Eating Disorders Review 2015, 24: 181-186. PMID: 26640009, PMCID: PMC5076468, DOI: 10.1002/erv.2417.Peer-Reviewed Original ResearchConceptsPrimary care settingEating-disorder psychopathologyCare settingsBiopsychosocial correlatesHigher diastolic blood pressureInstitute appropriate interventionsPoor glycaemic controlDiastolic blood pressurePhysical health functioningRacial differencesSignificant racial differencesBinge Eating DisorderAfrican AmericansAfrican American womenGlycaemic controlObese womenBlood pressureMetabolic syndromeClinical presentationCaucasian patientsDepressive symptomsComorbid bingeHealth functioningAppropriate interventionsEarly onset