Featured Publications
Weighty decisions: How symptom severity and weight impact perceptions of bulimia nervosa
Galbraith K, Elmquist J, White MA, Grilo CM, Lydecker JA. Weighty decisions: How symptom severity and weight impact perceptions of bulimia nervosa. International Journal Of Eating Disorders 2019, 52: 1035-1041. PMID: 31240769, PMCID: PMC6779161, DOI: 10.1002/eat.23125.Peer-Reviewed Original ResearchConceptsBulimia nervosaSymptom frequencySerious mental health concernsMental health concernsPatient weightWeight statusMental illnessSymptom severityOverweightYoung womenHealth concernWeight stigmaSignificant differencesPatientsNervosaCurrent studyParticipantsVariables of interestIllnessNegative attitudesSeverityWomenI didn't want them to see: Secretive eating among adults with binge‐eating disorder
Lydecker JA, Grilo CM. I didn't want them to see: Secretive eating among adults with binge‐eating disorder. International Journal Of Eating Disorders 2019, 52: 153-158. PMID: 30623972, PMCID: PMC6368878, DOI: 10.1002/eat.23002.Peer-Reviewed Original ResearchConceptsBody mass indexBinge-eating disorderEating-disorder psychopathologyObjective binge-eating episodesSecretive eatingBinge-eating episodesGreater eating-disorder psychopathologyGreater body mass indexHigher depression scoresClinical characteristicsMass indexTreatment-seeking adultsDepression scoresPatientsShape/weightWeight concernsAdultsEatingSelf-report measuresDisordersShape concernsEpisodesGreater proportionPsychopathologyTreatment formulationCognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial
Grilo C, Lydecker J, Gueorguieva R. Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial. International Journal Of Eating Disorders 2023, 56: 1544-1553. PMID: 37144325, PMCID: PMC10524840, DOI: 10.1002/eat.23975.Peer-Reviewed Original ResearchConceptsInitial acute treatmentBinge-eating disorderCognitive behavioral therapyAcute treatmentBinge-eating frequencyInitial interventionTherapist-led cognitive behavioural therapyInitial pharmacological treatmentTreat remission ratesEvidence-based treatmentsSingle-site trialAcute efficacyRemission rateAdult patientsInitial treatmentPharmacological treatmentPatientsPosttreatment assessmentBehavioral treatmentSufficient benefitTherapyDisordersInterventionTreatmentPharmacotherapy
2024
Trauma‐Focused Cognitive‐Behavioral Therapy for Adolescents Bullied Because of Weight: A Feasibility Study
Lydecker J, Ozbardakci E, Lou R, Grilo C. Trauma‐Focused Cognitive‐Behavioral Therapy for Adolescents Bullied Because of Weight: A Feasibility Study. International Journal Of Eating Disorders 2024, 57: 2117-2127. PMID: 39007703, DOI: 10.1002/eat.24257.Peer-Reviewed Original ResearchCognitive-behavioral therapyTraumatic stressClinically-meaningful improvementsTrauma-focused cognitive behavioral therapyTrauma-focused cognitive-behavioral therapyPatient outcomesOvervaluation of weight/shapeSymptoms of traumatic stressWeight-related bullyingCognitive behavioral therapyCognitive-behavioralTrauma-focusedWithin-subject improvementIntrusive symptomsBehavioral therapyDietary restraintEating disordersTherapyTreatment satisfactionFunctional impairmentTreatment feasibilityAdolescentsPatientsWeight/shapeFeasibility trial
2023
Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reduction
2021
Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder
Grilo CM, Kerrigan SG, Lydecker JA, White MA. Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder. Obesity 2021, 29: 2026-2034. PMID: 34582624, PMCID: PMC8612949, DOI: 10.1002/oby.23278.Peer-Reviewed Original ResearchConceptsBehavioral weight loss treatmentWeight loss treatmentLatinx patientsPhysical activity changesBWL treatmentReduced depressionCommunity mental health centerWeight lossPA changePlacebo-controlled trialAddition of orlistatMental health centersActivity changesPrognostic significanceMedication conditionHealth centersLoss treatmentPatientsObesitySecondary analysisClinical settingBed statusBaselineTreatmentDepression
2020
Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study
Grilo CM, Lydecker JA, Morgan PT, Gueorguieva R. Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study. Clinical Therapeutics 2020, 43: 112-122.e1. PMID: 33218742, PMCID: PMC7902424, DOI: 10.1016/j.clinthera.2020.10.010.Peer-Reviewed Original ResearchConceptsBinge-eating disorderEating-disorder psychopathologyPilot RCTTreatment of BEDOutcome time pointDouble-blind treatmentPercentage of patientsControlled Pilot StudyDiscontinuation of medicationTreatment of bingeEvidence-based treatmentsBinge-eating frequencyBupropion combinationAdult patientsAdverse eventsComorbid obesitySecondary outcomesPrimary outcomeAcute effectsFunctional impairmentPlaceboLong-term effectsPatientsMost outcomesObesityInterrater reliability of the Eating Disorder Examination among postbariatric patients
Wiedemann AA, Ivezaj V, Lawson JL, Lydecker JA, Cooper Z, Grilo CM. Interrater reliability of the Eating Disorder Examination among postbariatric patients. Surgery For Obesity And Related Diseases 2020, 16: 1988-1993. PMID: 32933867, PMCID: PMC7704555, DOI: 10.1016/j.soard.2020.07.032.Peer-Reviewed Original ResearchConceptsEating Disorder ExaminationIntraclass correlation coefficientEating-disorder psychopathologyBariatric surgerySurgery patientsInterrater reliabilityPostoperative bariatric surgery patientsDisorder ExaminationPostbariatric surgery patientsBariatric surgery patientsBariatric surgery sampleBinge-eating episodesSemistructured clinical interviewPostbariatric patientsBariatric patientsConsecutive seriesClinical assessmentSurgery samplesClinical InterviewPatientsSymptom presentationKappa agreementInitial evaluationEDE subscalesExpert ratersLanguage Matters: Patients’ Preferred Terms for Discussing Obesity and Disordered Eating with Health Care Providers After Bariatric Surgery
Ivezaj V, Lydecker JA, Grilo CM. Language Matters: Patients’ Preferred Terms for Discussing Obesity and Disordered Eating with Health Care Providers After Bariatric Surgery. Obesity 2020, 28: 1412-1418. PMID: 32662251, PMCID: PMC7501175, DOI: 10.1002/oby.22868.Peer-Reviewed Original ResearchConceptsHealth care providersBariatric surgeryCare providersCross-sectional studyPatient-centered carePreferred termHealth care systemTreatment trialsPatient preferencesSurgeryBehavioral treatmentControl eatingLanguage preferenceCare systemRacial differencesObesityPatientsWeight biasProvidersBMIWeightIndividualsControlTrialsCareInternalized weight bias and loss-of-control eating following bariatric surgery
Lawson JL, LeCates A, Ivezaj V, Lydecker J, Grilo CM. Internalized weight bias and loss-of-control eating following bariatric surgery. Eating Disorders 2020, 29: 630-643. PMID: 32182194, PMCID: PMC7494529, DOI: 10.1080/10640266.2020.1731920.Peer-Reviewed Original ResearchConceptsEating Disorder Examination-Bariatric Surgery Version interviewEating-disorder psychopathologyBariatric surgeryWeight biasGreater eating-disorder psychopathologyPercent excess weight lossEating Disorder FeaturesInternalized weight biasExcess weight lossHierarchical regression analysisControl eatingPsychosocial difficultiesGastrectomy patientsAdult patientsClinical presentationGastrectomy surgeryPrognostic significanceWeight concernsClinical correlatesEstablished measuresNon-White participantsSurgeryPatientsPsychopathologyMental quality
2019
Secretive eating and binge eating following bariatric surgery
Lydecker JA, Ivezaj V, Grilo CM. Secretive eating and binge eating following bariatric surgery. International Journal Of Eating Disorders 2019, 52: 935-940. PMID: 31033037, PMCID: PMC6687553, DOI: 10.1002/eat.23089.Peer-Reviewed Original ResearchConceptsBariatric surgerySecretive eatingClinical variablesDisorder psychopathologyPost-bariatric surgery patientsBed statusBinge-eating disorderBinge-eating episodesInvestigator-based interviewSurgery patientsTreatment-seeking adultsPatientsBariatric bedsControl eatingSurgeryDepression measuresWeight concernsStrong associationRelevant markersPsychopathology severityEatingShape concernsSize criteriaPsychopathologyAdults
2017
Characteristics of Weight Loss Trajectories in a Comprehensive Lifestyle Intervention
Marek RJ, Coulon SM, Brown JD, Lydecker JA, Marek S, Malcolm R, O'Neil PM. Characteristics of Weight Loss Trajectories in a Comprehensive Lifestyle Intervention. Obesity 2017, 25: 2062-2067. PMID: 29086487, DOI: 10.1002/oby.21942.Peer-Reviewed Original ResearchConceptsWeight loss trajectoriesAverage weight lossWeight lossLifestyle interventionWeight changeWeight gainComprehensive lifestyle interventionLatent class analysisMeal replacement dietMore tailored interventionsLifestyle change counselingWeekly weight changesWeekly weight gainPercent weight lossLess optimal outcomesLifestyle programEfficacy dataGroup 2Group 1Group 3Class analysisPatientsTailored interventionsOptimal outcomesPercent weight gain
2016
Preferred descriptions for loss of control while eating and weight among patients with binge eating disorder
Roberto CA, Galbraith K, Lydecker JA, Ivezaj V, Barnes RD, White MA, Grilo CM. Preferred descriptions for loss of control while eating and weight among patients with binge eating disorder. Psychiatry Research 2016, 246: 548-553. PMID: 27821368, PMCID: PMC5161684, DOI: 10.1016/j.psychres.2016.09.045.Peer-Reviewed Original Research