2015
The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576)
Weisman O, Pelphrey KA, Leckman JF, Feldman R, Lu Y, Chong A, Chen Y, Monakhov M, Chew SH, Ebstein RP. The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576). Psychoneuroendocrinology 2015, 58: 23-32. PMID: 25935637, DOI: 10.1016/j.psyneuen.2015.04.007.Peer-Reviewed Original ResearchConceptsOxytocin receptor geneCognitive empathyRMET performanceFetal testosteroneHuman social cognitionSocial-cognitive developmentSocio-cognitive skillsRole of oxytocinSocio-affective skillsSocial cognitionPsychosocial competenceHigh fetal testosteroneIndividual differencesCognitive developmentBaron-CohenEmotional statesOXTR rs53576OXTR geneGreater identificationEmpathyCore aspectsRMETCognitionUnique supportTestosterone system
2009
Autism spectrum and obsessive–compulsive disorders: OC behaviors, phenotypes and genetics
Jacob S, Landeros‐Weisenberger A, Leckman JF. Autism spectrum and obsessive–compulsive disorders: OC behaviors, phenotypes and genetics. Autism Research 2009, 2: 293-311. PMID: 20029829, PMCID: PMC3974607, DOI: 10.1002/aur.108.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsChildChild Development Disorders, PervasiveChild, PreschoolComorbidityDiagnosis, DifferentialDisease Models, AnimalDiseases in TwinsGenetic Association StudiesGenetic Predisposition to DiseaseGenotypeHumansInfantIntellectual DisabilityInterview, PsychologicalNeuropsychological TestsObsessive-Compulsive DisorderPhenotypeQuantitative Trait, HeritableStereotyped BehaviorConceptsAutism spectrum disorderObsessive-compulsive behaviorObsessive-compulsive disorderNovel treatment interventionsFamily genetic studiesAutism spectrumGeneralist genesOC behaviorSpectrum disorderRare genetic variantsASD variesHeritable endophenotypeASD phenotypeCandidate gene studiesNovel genomic technologiesNonparametric linkage analysisInnovative statistical approachChronological ageGenetic mechanismsGenomic technologiesTreatment interventionsGenetic analysisGenetic influencesLinkage analysisGene studies