2010
Elevated expression of MCP-1, IL-2 and PTPR-N in basal ganglia of Tourette syndrome cases
Morer A, Chae W, Henegariu O, Bothwell AL, Leckman JF, Kawikova I. Elevated expression of MCP-1, IL-2 and PTPR-N in basal ganglia of Tourette syndrome cases. Brain Behavior And Immunity 2010, 24: 1069-1073. PMID: 20193755, DOI: 10.1016/j.bbi.2010.02.007.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAutopsyBasal GangliaChemokine CCL2FemaleHumansInterferon-gammaInterleukin-1betaInterleukin-2Leukocyte Common AntigensMaleMiddle AgedPolymerase Chain ReactionReceptor-Like Protein Tyrosine Phosphatases, Class 2Receptor-Like Protein Tyrosine Phosphatases, Class 8RecoverinRNATourette SyndromeConceptsMCP-1IL-2Tourette syndromePost-mortem specimenBasal gangliaElevated expressionPost-infectious autoimmunityAdult TS patientsChronic inflammatory processEvidence of inflammationBasal ganglia areaInterleukin-1 βCentral nervous systemChemotactic factor-1TS casesReverse transcription-polymerase chain reaction analysisTranscription-polymerase chain reaction analysisReal-time reverse transcription-polymerase chain reaction analysisBrain tissue sectionsInflammatory factorsControl subjectsGanglia areaInflammatory processInterleukin-2TS patients
1991
Detection of homeobox genes in development and evolution.
Murtha MT, Leckman JF, Ruddle FH. Detection of homeobox genes in development and evolution. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 10711-10715. PMID: 1720547, PMCID: PMC53000, DOI: 10.1073/pnas.88.23.10711.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBiological EvolutionCiona intestinalisCodonDipteraDrosophilaEmbryo, MammalianEmbryo, NonmammalianGenes, HomeoboxMaleMiceMolecular Sequence DataOligodeoxyribonucleotidesPolymerase Chain ReactionRestriction MappingRNASequence Homology, Nucleic AcidTelencephalonConceptsHomeobox genesHomeobox sequencesDNA-binding regulatory proteinsDiverse metazoan speciesSurvey of sequencesMouse genomic DNAImportant model systemPopulations of DNAMetazoan speciesAncient roleMetazoan evolutionPolymerase chain reactionGenomic organizationDrosophila H2.0Regulatory proteinsHlx geneGenomic DNAStudy of developmentMouse telencephalonNovel sequencesGenesOligonucleotide primersHomeodomainModel systemRNA