2005
A family study of early‐onset obsessive‐compulsive disorder
do Rosario‐Campos M, Leckman JF, Curi M, Quatrano S, Katsovitch L, Miguel EC, Pauls DL. A family study of early‐onset obsessive‐compulsive disorder. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2005, 136B: 92-97. PMID: 15892140, DOI: 10.1002/ajmg.b.30149.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderRecurrence riskChronic ticsFirst-degree family membersChildhood-onset obsessive-compulsive disorderDiagnosis of OCDChronic tic disorderStandardized semi-structured interviewFirst-degree relativesEarly-onset casesOnset obsessive-compulsive disorderDSM-IV criteriaEarly-onset obsessive-compulsive disorderBest-estimate processRandom digit dialingHigh comorbid ratesAge of onsetFamily studiesHigh genetic loadingMean ageSpecialty clinicTic disordersComorbid ratesValid subgroupsCase relatives
2003
Influence of Age and Tic Disorders on Obsessive-Compulsive Disorder in a Pediatric Sample
Scahill L, Kano Y, King RA, Carlson A, Peller A, LeBrun U, do Rosario-Campos MC, Leckman JF. Influence of Age and Tic Disorders on Obsessive-Compulsive Disorder in a Pediatric Sample. Journal Of Child And Adolescent Psychopharmacology 2003, 13: 7-17. PMID: 12880496, DOI: 10.1089/104454603322126304.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderTic disordersAge of onsetAge groupsPediatric samplesAbsence of ticsHistory of ticsAdolescent age groupImpact of ageInfluence of agePresence of ticsMean ageFunctional statusOnly significant differenceSpecialty clinicSymptom profilesHeterogeneous disorderImportant subgroupSymptom typeDisordersCommon compulsionsAge categoriesCompulsive disorderAgeConvenient sample