FUTURE THERAPIES OF TOURETTE SYNDROME * *Portions of this article have previously appeared in Chappell PB, Leckman JF, Riddle MA: The pharmacologic treatment of tic disorders. Child Adolesc Psychiatr Clin North Am. 4:197, 1995.
Chappell PB, Scahill LD, Leckman JF. FUTURE THERAPIES OF TOURETTE SYNDROME * *Portions of this article have previously appeared in Chappell PB, Leckman JF, Riddle MA: The pharmacologic treatment of tic disorders. Child Adolesc Psychiatr Clin North Am. 4:197, 1995. Neurologic Clinics 1997, 15: 429-450. PMID: 9115473, DOI: 10.1016/s0733-8619(05)70324-8.Peer-Reviewed Original ResearchConceptsTourette syndromeNew atypical antipsychotic medicationsCorticotropin-releasing factor antagonistAmino acid neurotransmitter systemsUnacceptable side effect profileAvailable pharmacologic therapiesNewer atypical antipsychoticsTreatment of ticsSide effect profileSubgroup of patientsAtypical antipsychotic medicationsTourette syndrome patientsLong-term courseReceptor affinity profileNonpharmacologic interventionsPharmacologic therapyPharmacologic treatmentAtypical antipsychoticsEffect profileAntipsychotic medicationTic disordersNeurotransmitter systemsSyndrome patientsFactor antagonistsSet of symptoms