2022
Antithrombotic Therapy After Left Atrial Appendage Occlusion in Patients With Atrial Fibrillation
Freeman JV, Higgins AY, Wang Y, Du C, Friedman DJ, Daimee UA, Minges KE, Pereira L, Goldsweig AM, Price MJ, Reddy VY, Gibson D, Doshi SK, Varosy PD, Masoudi FA, Curtis JP. Antithrombotic Therapy After Left Atrial Appendage Occlusion in Patients With Atrial Fibrillation. Journal Of The American College Of Cardiology 2022, 79: 1785-1798. PMID: 35512858, PMCID: PMC9097170, DOI: 10.1016/j.jacc.2022.02.047.Peer-Reviewed Original ResearchConceptsLeft atrial appendage occlusionAdverse eventsPivotal trialsWatchman deviceTreatment protocolAntithrombotic strategiesAppendage occlusionLower riskFrailty regressionPercutaneous left atrial appendage occlusionNational Cardiovascular Data RegistryContemporary U.S. practiceDual antiplatelet therapyAtrial appendage occlusionConcomitant aspirinPostprocedure careAdjusted riskAntiplatelet therapyAntithrombotic medicationAntithrombotic therapyAtrial fibrillationAdverse outcomesTrial protocolAntithrombotic agentsMedication strategies
2017
Treatment of Atrial Fibrillation and Concordance With the American Heart Association/American College of Cardiology/Heart Rhythm Society Guidelines
Barnett AS, Kim S, Fonarow GC, Thomas LE, Reiffel JA, Allen LA, Freeman JV, Naccarelli G, Mahaffey KW, Go AS, Kowey PR, Ansell JE, Gersh BJ, Hylek EM, Peterson ED, Piccini JP. Treatment of Atrial Fibrillation and Concordance With the American Heart Association/American College of Cardiology/Heart Rhythm Society Guidelines. Circulation Arrhythmia And Electrophysiology 2017, 10: e005051. PMID: 29141842, DOI: 10.1161/circep.117.005051.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmerican Heart AssociationAtrial FibrillationCardiologistsFemaleGuideline AdherenceHealthcare DisparitiesHumansMaleMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Process Assessment, Health CareQuality Indicators, Health CareRegistriesRetrospective StudiesTime FactorsTreatment OutcomeUnited StatesConceptsAmerican Heart Association/American CollegeAtrial fibrillationGuideline recommendationsAmerican CollegeCardiology/Heart Rhythm Society GuidelinesHeart Rhythm Society guidelinesAtrial fibrillation guidelinesGuideline-concordant careThird of patientsRisk-adjusted outcomesAntiarrhythmic medicationsGuideline concordanceMajor bleedingMedian CHAOutpatient registryVASc scoreAntithrombotic therapyCause hospitalizationMedian ageClinical outcomesSociety guidelinesORBIT-AFImproved outcomesPatient levelSimilar risk