2005
Human Monocytotropic Ehrlichiosis
Dawson J, Ewing S, Davidson W, Childs J, Little S, Standaert S. Human Monocytotropic Ehrlichiosis. 2005, 239-257. DOI: 10.1128/9781555816490.ch14.Peer-Reviewed Original ResearchHuman monocytotropic ehrlichiosisMonocytotropic ehrlichiosisMild self-limiting symptomsSelf-limiting symptomsNonspecific febrile illnessSpectrum of manifestationsSeasonality of transmissionTick-borne zoonosisFebrile illnessAsymptomatic infectionClinical recognitionHigh riskRickettsial infectionEpidemiological studiesEtiologic agentFatal diseaseLaboratory diagnosisZoonotic diseaseEhrlichia chaffeensisLone star tickE. chaffeensisInfectionDiseaseEhrlichiosisUnited States
2001
Clinical and Serological Follow-Up of Patients with Human Granulocytic Ehrlichiosis in Slovenia
Lotrič-Furlan S, Avsic-Zupanc T, Petrovec M, Nicholson W, Sumner J, Childs J, Strle F. Clinical and Serological Follow-Up of Patients with Human Granulocytic Ehrlichiosis in Slovenia. MSphere 2001, 8: 899-903. PMID: 11527800, PMCID: PMC96168, DOI: 10.1128/cdli.8.5.899-903.2001.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisAntibody titersTick biteLong-term clinical consequencesGranulocytic ehrlichiosisIFA antibody titersOnset of feverSerological Follow-UpHigh antibody titersMost time pointsSeronegative patientsSeropositive patientsAdult patientsFebrile illnessPatients 6Initial presentationClinical outcomesAntibody responseClinical evaluationFollow-upReciprocal titersClinical consequencesSerum collectionFirst presentationPatientsProspective Assessment of the Etiology of Acute Febrile Illness after a Tick Bite in Slovenia
Lotrič-Furlan S, Petrovec M, Avsic-Zupanc T, Nicholson W, Sumner J, Childs J, Strle F. Prospective Assessment of the Etiology of Acute Febrile Illness after a Tick Bite in Slovenia. Clinical Infectious Diseases 2001, 33: 503-510. PMID: 11462187, DOI: 10.1086/322586.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnimalsBites and StingsBorrelia burgdorferi GroupCohort StudiesEhrlichiaEhrlichia chaffeensisEhrlichiosisEncephalitis Viruses, Tick-BorneEncephalitis, Tick-BorneFemaleFeverHumansLyme DiseaseMaleMiddle AgedProspective StudiesSloveniaTick-Borne DiseasesTicksConceptsFebrile illnessTick biteEhrlichia phagocytophila infectionAcute febrile illnessTickborne diseasesEvidence of infectionBorrelia burgdorferi sensu latoMeningeal involvementProspective studyClinical criteriaBurgdorferi sensu latoTickborne encephalitisProspective assessmentPatientsLaboratory evidenceImportant causeBacterial infectionsIllnessLyme borreliosisInfectionDiseaseResidents of SloveniaEtiologyBiteEncephalitis
2000
Primary Isolation of Ehrlichia chaffeensis from Patients with Febrile Illnesses: Clinical and Molecular Characteristics
Standaert S, Yu T, Scott M, Childs J, Paddock C, Nicholson W, Singleton J, Blaser M. Primary Isolation of Ehrlichia chaffeensis from Patients with Febrile Illnesses: Clinical and Molecular Characteristics. The Journal Of Infectious Diseases 2000, 181: 1082-1088. PMID: 10720534, DOI: 10.1086/315346.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionE. chaffeensisCerebrospinal fluid specimensCultures of bloodHigh diagnostic yieldEhrlichia chaffeensisPrimary isolationFebrile illnessDiagnostic titerBlood isolatesDiagnostic yieldTick exposureSame patientCerebrospinal fluidPatientsFluid specimensDiagnostic testsFrequent isolationBloodChain reactionChaffeensisInfectionMolecular characteristicsMolecular analysisIsolates
1999
Serologic evidence of rickettsialpox (Rickettsia akari) infection among intravenous drug users in inner-city Baltimore, Maryland.
Comer J, Tzianabos T, Flynn C, Vlahov D, Childs J. Serologic evidence of rickettsialpox (Rickettsia akari) infection among intravenous drug users in inner-city Baltimore, Maryland. American Journal Of Tropical Medicine And Hygiene 1999, 60: 894-8. PMID: 10403316, DOI: 10.4269/ajtmh.1999.60.894.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, BacterialBaltimoreCohort StudiesCross ReactionsDrinkingFemaleFluorescent Antibody Technique, IndirectHIV SeropositivityHumansIll-Housed PersonsMaleRickettsiaRickettsia InfectionsRickettsia rickettsiiRisk FactorsSeroepidemiologic StudiesSubstance Abuse, IntravenousUrban PopulationConceptsIntravenous drug usersInner-city BaltimoreDrug usersSerologic evidenceSerum samplesAcute febrile illnessR. rickettsiiR. akariHuman immunodeficiency virusSignificant risk factorsSignificant inverse associationCross-adsorption studiesPresence of antibodiesSingle serum sampleR. akari infectionFrequency of injectionsFever group rickettsiaeFebrile illnessUndetermined etiologyImmunodeficiency virusInverse associationRisk factorsGroup-specific antibodiesDrug useHigh titers
1998
Human ehrlichiosis in central Europe.
Lotric-Furlan S, Petrovec M, Avsic-Zupanc T, Nicholson W, Sumner J, Childs J, Strle F. Human ehrlichiosis in central Europe. Wiener Klinische Wochenschrift 1998, 110: 894-7. PMID: 10048172.Peer-Reviewed Original ResearchConceptsFebrile illnessTick biteHGE agentPresence of infectionUniversity Medical CenterBlood smear examinationHuman granulocytic ehrlichiosis (HGE) agentEhrlichiosis casesAcute human diseaseClinical characteristicsAntibiotic therapyDisease coursePhysician awarenessProspective studyLaboratory findingsDifferential diagnosisMedical CenterSmear examinationHuman diseasesHuman ehrlichiosisNumber of casesPatientsHuman infectionsInfectious diseasesDiseaseHuman Granulocytic Ehrlichiosis in Europe: Clinical and Laboratory Findings for Four Patients from Slovenia
Lotrič-Furlan S, Petrovec M, Zupanc T, Nicholson W, Sumner J, Childs J, Strle F. Human Granulocytic Ehrlichiosis in Europe: Clinical and Laboratory Findings for Four Patients from Slovenia. Clinical Infectious Diseases 1998, 27: 424-428. PMID: 9770134, DOI: 10.1086/514683.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisHGE agentFebrile illnessLaboratory findingsTick biteAcute human granulocytic ehrlichiosisGranulocytic ehrlichiosisTick-borne diseaseAcute infectionAntibiotic therapyDisease coursePolymerase chain reaction analysisClinical featuresDetectable antibodiesDifferential diagnosisFirst visitChain reaction analysisPatientsHigh titersIllnessEhrlichial organismsEhrlichiosisAntibodiesBiteUnited States