1999
Outcome of Diagnostic Tests Using Samples from Patients with Culture-Proven Human Monocytic Ehrlichiosis: Implications for Surveillance
Childs J, Sumner J, Nicholson W, Massung R, Standaert S, Paddock C. Outcome of Diagnostic Tests Using Samples from Patients with Culture-Proven Human Monocytic Ehrlichiosis: Implications for Surveillance. Journal Of Clinical Microbiology 1999, 37: 2997-3000. PMID: 10449489, PMCID: PMC85432, DOI: 10.1128/jcm.37.9.2997-3000.1999.Peer-Reviewed Original ResearchConceptsHuman monocytic ehrlichiosisDiagnosis of HMEConvalescent-phase serum samplesMonocytic ehrlichiosisDetection of morulaeInitial clinical presentationCulture-proven casesE. chaffeensis antigenWhole blood specimensCompatible illnessClinical presentationInitial presentationSerologic responseCase definitionHME patientsBlood specimensImmunoglobulin MPatientsBlood smearsIndirect immunofluorescenceEhrlichial DNADiagnostic testsSerum samplesProbable diseaseEhrlichia chaffeensis
1998
Epidemiology of human rabies in the United States, 1980 to 1996.
Noah D, Drenzek C, Smith J, Krebs J, Orciari L, Shaddock J, Sanderlin D, Whitfield S, Fekadu M, Olson J, Rupprecht C, Childs J. Epidemiology of human rabies in the United States, 1980 to 1996. Annals Of Internal Medicine 1998, 128: 922-30. PMID: 9634432, DOI: 10.7326/0003-4819-128-11-199806010-00012.Peer-Reviewed Original ResearchConceptsPostexposure prophylaxisHuman rabiesAnimal bitesBat bitesRabies virus variantVirus variantsLaboratory-confirmed casesMedical personnelExposure historyDiagnostic laboratory testsLocal health authoritiesDiagnosis of rabiesRabies virus transmissionInfectious salivaInsignificant woundMost patientsClinical courseClinical featuresClinical presentationDefinite historyAntemortem diagnosisCase reportClinical differencesClinical signsDifferential diagnosis
1997
Isolation and characterization of Ehrlichia chaffeensis strains from patients with fatal ehrlichiosis
Paddock C, Sumner J, Shore G, Bartley D, Elie R, McQuade J, Martin C, Goldsmith C, Childs J. Isolation and characterization of Ehrlichia chaffeensis strains from patients with fatal ehrlichiosis. Journal Of Clinical Microbiology 1997, 35: 2496-2502. PMID: 9316896, PMCID: PMC229999, DOI: 10.1128/jcm.35.10.2496-2502.1997.Peer-Reviewed Original ResearchConceptsE. chaffeensisDH82 cellsEhrlichia chaffeensisArkansas isolateGroESL heat shock operonFatal ehrlichiosisMechanisms of diseasePulmonary insufficiencyClinical presentationMarked thrombocytopeniaSevere diseaseEhrlichial infectionCharacteristic manifestationsPatientsDays postinoculationMolecular evaluationChaffeensisPrimary isolationRRNA gene sequencesDiseaseIsolatesSpecific associationNew isolatesGene sequencesProtein gene