1999
Population Dynamics of a Naturally Occurring Heterogeneous Mixture of Borrelia burgdorferiClones
Hofmeister E, Glass G, Childs J, Persing D. Population Dynamics of a Naturally Occurring Heterogeneous Mixture of Borrelia burgdorferiClones. Infection And Immunity 1999, 67: 5709-5716. PMID: 10531219, PMCID: PMC96945, DOI: 10.1128/iai.67.11.5709-5716.1999.Peer-Reviewed Original ResearchConceptsC3H/HeJ miceC.B-17 miceLarval Ixodes scapularis ticksMajority of miceB. burgdorferiInfected nymphal ticksIxodes scapularis ticksBurgdorferi antibodiesSecondary challengeHeJ micePrimary isolatesSequential isolatesC3H miceSequential infectionMiceMonoclonal antibodiesBorrelia burgdorferiC expressionScapularis ticksClonal dominanceUnique isolatesMacrorestriction analysisOspC proteinsClonal groupsEnzootic siteLongitudinal study of infection with Borrelia burgdorferi in a population of Peromyscus leucopus at a Lyme disease-enzootic site in Maryland.
Hofmeister E, Ellis B, Glass G, Childs J. Longitudinal study of infection with Borrelia burgdorferi in a population of Peromyscus leucopus at a Lyme disease-enzootic site in Maryland. American Journal Of Tropical Medicine And Hygiene 1999, 60: 598-609. PMID: 10348235, DOI: 10.4269/ajtmh.1999.60.598.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionB. burgdorferiJuvenile miceCross-sectional sampleEar tissueBorrelia burgdorferi infectionIxodes scapularis ticksInfected miceSusceptible miceChronic infectionOverall prevalenceIncidence rateBurgdorferi infectionHigh riskLower riskInfectionMiceInfected ticksLongitudinal sampleBorrelia burgdorferiScapularis ticksChain reactionBurgdorferiLongitudinal studyIndirect transmission
1995
EAR BIOPSY LOCATION INFLUENCES DETECTION OF BORRELIA BURGDORFERI BY PCR, BUT NOT BY CULTURE IN NATURALLY INFECTED PEROMYSCUS LEUCOPUS
Hofmeister E, Childs J. EAR BIOPSY LOCATION INFLUENCES DETECTION OF BORRELIA BURGDORFERI BY PCR, BUT NOT BY CULTURE IN NATURALLY INFECTED PEROMYSCUS LEUCOPUS. Journal Of Wildlife Diseases 1995, 31: 345-351. PMID: 8592355, DOI: 10.7589/0090-3558-31.3.345.Peer-Reviewed Original ResearchConceptsEar biopsy samplesPolymerase chain reactionBiopsy samplesBiopsy locationB. burgdorferiBorrelia burgdorferiInfected micePeripheral samplesIndividual miceInfection statusMore tissue samplesMiceTissue samplesHigh concordanceChain reactionOrgan cultureBurgdorferiGreater frequencyEar samplesWhite-footed miceEnzootic areaEarCentral sample
1992
Comparison of polymerase chain reaction and culture for detection of Borrelia burgdorferi in naturally infected Peromyscus leucopus and experimentally infected C.B-17 scid/scid mice
Hofmeister E, Markham R, Childs J, Arthur R. Comparison of polymerase chain reaction and culture for detection of Borrelia burgdorferi in naturally infected Peromyscus leucopus and experimentally infected C.B-17 scid/scid mice. Journal Of Clinical Microbiology 1992, 30: 2625-2631. PMID: 1400962, PMCID: PMC270489, DOI: 10.1128/jcm.30.10.2625-2631.1992.Peer-Reviewed Original Research