Activation of pial and dural macrophages and dendritic cells by cortical spreading depression
Schain AJ, Melo‐Carrillo A, Borsook D, Grutzendler J, Strassman AM, Burstein R. Activation of pial and dural macrophages and dendritic cells by cortical spreading depression. Annals Of Neurology 2018, 83: 508-521. PMID: 29394508, PMCID: PMC5965700, DOI: 10.1002/ana.25169.Peer-Reviewed Original ResearchConceptsBlood-brain barrierDendritic cellsDural macrophagesImmune cellsAnatomical relationshipMigratory dendritic cellsAnn NeurolTRPV1 axonsMeningeal nociceptorsHead painMigraine attacksNociceptor activationSubarachnoid spaceMeningeal macrophagesMacrophagesCortical eventsAxonsActivationAuraDuraDepressionMinutesCellsCellular eventsCSD