2024
Plasma oxidative stress marker levels related to functional brain abnormalities in first-episode drug-naive major depressive disorder
Liu Y, Zhang B, Zhou Y, Li M, Gao Y, Qin W, Xie Y, Liu W, Jing Y, Li J. Plasma oxidative stress marker levels related to functional brain abnormalities in first-episode drug-naive major depressive disorder. Psychiatry Research 2024, 333: 115742. PMID: 38232568, DOI: 10.1016/j.psychres.2024.115742.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingDepressive Disorder, MajorGyrus CinguliHumansMagnetic Resonance ImagingSuperoxide DismutaseConceptsMajor depressive disorderMajor depressive disorder patientsAmplitude of low-frequency fluctuationDepressive disorderSuicidal ideationWhole-brain functional connectivity analysisMDD pathophysiologyDrug-naive MDD patientsResting-state fMRI scansAmplitude of low-frequency fluctuation valuesFunctional brain abnormalitiesAnterior cingulate gyrusSuperior frontal gyrusFunctional connectivity analysisOxidative stress markersAbnormal brain functionLow-frequency fluctuationsPlasma oxidative stress markersMDD patientsFrontal gyrusFMRI scanningFirst-episodeCingulate gyrusBrain regionsConnectivity analysis
2022
Abnormal dynamic functional network connectivity in first-episode, drug-naïve patients with major depressive disorder
Yang W, Wang Y, Qin W, Li M, Mao H, Zhou C, Liu X, Li J. Abnormal dynamic functional network connectivity in first-episode, drug-naïve patients with major depressive disorder. Journal Of Affective Disorders 2022, 319: 336-343. PMID: 36084757, DOI: 10.1016/j.jad.2022.08.072.Peer-Reviewed Original ResearchConceptsHamilton Depression Rating ScaleFirst-episodeDrug-naive patientsFunctional network connectivityDynamic functional network connectivityFeatures of spontaneous brain activityDepression Rating ScaleFunctional brain networksSpontaneous brain activityGender-matched healthy controlsMDD patientsDepressive disorderReceiver operating characteristicDepressive symptomsMDDBrain networksBrain activityConnectivity statesRating ScaleReceiver operating characteristic curve analysisHealthy controlsNetwork connectivityMRI scansDiagnostic performanceCurve analysis