The effect of berberine adjunctive treatment on glycolipid metabolism in patients with schizophrenia: A randomized, double-blind, placebo-controlled clinical trial
Li M, Liu Y, Qiu Y, Zhang J, Zhang Y, Zhao Y, Jia Q, Li J. The effect of berberine adjunctive treatment on glycolipid metabolism in patients with schizophrenia: A randomized, double-blind, placebo-controlled clinical trial. Psychiatry Research 2021, 300: 113899. PMID: 33812218, DOI: 10.1016/j.psychres.2021.113899.Peer-Reviewed Original ResearchMeSH KeywordsAntipsychotic AgentsBerberineDouble-Blind MethodGlycolipidsHumansSchizophreniaTreatment OutcomeConceptsAdjunctive treatmentNon-psychiatric patientsDouble-blindSerum prolactin concentrationsPlacebo-controlled clinical trialSchizophreniaMetabolic disturbancesGlycolipid metabolic parametersBaseline body mass indexImprove metabolic disturbancesLow-density lipoprotein cholesterolProlactin concentrationsSixty-five patientsFasting serum insulinWeek 8Body mass indexEffects of berberineLipoprotein cholesterolMass indexPlaceboWeek 4Previous studiesClinical trialsMetabolic parametersTotal cholesterol