Emerging Roles of Cullin-RING Ubiquitin Ligases in Cardiac Development
Zambrano-Carrasco J, Zou J, Wang W, Sun X, Li J, Su H. Emerging Roles of Cullin-RING Ubiquitin Ligases in Cardiac Development. Cells 2024, 13: 235. PMID: 38334627, PMCID: PMC10854628, DOI: 10.3390/cells13030235.Peer-Reviewed Original ResearchConceptsUbiquitin ligaseFamily of ubiquitin ligasesCullin-RING ubiquitin ligasesE3 ubiquitin ligaseRegulation of heart developmentPost-translational mechanismsHeart developmentRegulation of cardiac morphogenesisCongenital heart diseaseCardiac developmental processesSpatiotemporally regulated processCullin-RINGDevelopment of innovative therapiesEpigenetic regulationIntracellular proteinsLigaseMolecular mechanismsDevelopmental processesHeart failureInnovative therapiesCardiac developmentCardiac morphogenesisPostnatal stagesHeart diseaseOrchestrated process