Sex differences and risk factors of self-reported suicide attempts in middle-aged Chinese Han patients with first-episode drug-naïve anxious depression: a large-scale cross-sectional study
Luo G, Wang S, Gou L, Li C, Yao C, Jing Y, Xuekelaiti Z, Li J, Zhang X. Sex differences and risk factors of self-reported suicide attempts in middle-aged Chinese Han patients with first-episode drug-naïve anxious depression: a large-scale cross-sectional study. Journal Of Neural Transmission 2024, 131: 987-998. PMID: 38743092, DOI: 10.1007/s00702-024-02779-x.Peer-Reviewed Original ResearchFirst-episode drug-naiveSelf-reported suicide attemptsAnxious depressionSuicide attemptsSex differencesHamilton Anxiety Rating Scale scoresAnxiety Rating Scale scoresClinical characteristics of suicide attemptersCharacteristics of suicide attemptersMajor depressive disorderNon-suicide attemptersSelf-reported suicidalityAD patientsRating Scale scoresInvestigate sex differencesMale AD patientsDepressive disorderDrug-naiveClinical psychiatristsSevere anxietySex-specific risk factorsMiddle-aged patientsDepressionThyroid peroxidase antibodyScale scoreThe association of FKBP5 gene polymorphism with genetic susceptibility to depression and response to antidepressant treatment- a systematic review
Zhang Y, Yue W, Li J. The association of FKBP5 gene polymorphism with genetic susceptibility to depression and response to antidepressant treatment- a systematic review. BMC Psychiatry 2024, 24: 274. PMID: 38609904, PMCID: PMC11010372, DOI: 10.1186/s12888-024-05717-z.Peer-Reviewed Original ResearchConceptsFKBP5 gene polymorphismsAntidepressant treatmentGene polymorphismsResponse to antidepressant treatmentAntidepressant drug treatmentGenetic susceptibilityAffective disordersAssociated with adverse reactionsDepressionTreatment strategiesAdverse reactionsFKBP5Drug treatmentTreatment sensitivityMethodsElectronic databasesGenetic disordersRs1360780Epigenetic changesReplication studySystematic reviewModerate qualityStudy characteristicsTreatmentData extractionDisorders