The association of FKBP5 gene polymorphism with genetic susceptibility to depression and response to antidepressant treatment- a systematic review
Zhang Y, Yue W, Li J. The association of FKBP5 gene polymorphism with genetic susceptibility to depression and response to antidepressant treatment- a systematic review. BMC Psychiatry 2024, 24: 274. PMID: 38609904, PMCID: PMC11010372, DOI: 10.1186/s12888-024-05717-z.Peer-Reviewed Original ResearchConceptsFKBP5 gene polymorphismsAntidepressant treatmentGene polymorphismsResponse to antidepressant treatmentAntidepressant drug treatmentGenetic susceptibilityAffective disordersAssociated with adverse reactionsDepressionTreatment strategiesAdverse reactionsFKBP5Drug treatmentTreatment sensitivityMethodsElectronic databasesGenetic disordersRs1360780Epigenetic changesReplication studySystematic reviewModerate qualityStudy characteristicsTreatmentData extractionDisorders