2012
Prazosin for Treatment of Patients With PTSD and Comorbid Alcohol Dependence
Petrakis I, Ralevski E. Prazosin for Treatment of Patients With PTSD and Comorbid Alcohol Dependence. 2012 DOI: 10.21236/ada568060.Peer-Reviewed Original ResearchAlpha-1 adrenergic receptor antagonistComorbid alcohol dependenceAdrenergic receptor antagonistAlcohol dependenceReceptor antagonistAlcohol consumptionDouble-blind fashionCommon comorbid conditionsTreatment of patientsRates of PTSDCommon neurobiological mechanismsTraumatic Stress DisorderSymptoms of PTSDComorbid conditionsSleep disturbancesEffective treatmentGeneral populationTrauma nightmaresPrazosinCurrent diagnosisPatientsStress disorderNeurobiological mechanismsPTSD symptomsSymptoms
2011
Prazosin for Treatment of Patients with PTSD and Comorbid Alcohol Dependence
Petrakis I. Prazosin for Treatment of Patients with PTSD and Comorbid Alcohol Dependence. 2011 DOI: 10.21236/ada554540.Peer-Reviewed Original ResearchComorbid alcohol dependenceAdrenergic receptor antagonistAlcohol dependenceReceptor antagonistSymptoms of PTSDAlcohol consumptionTraumatic Stress DisorderCommon neurobiological mechanismsDouble-blind fashionRates of PTSDTreatment of patientsPTSD symptomsStress disorderNeurobiological mechanismsCombat veteransPTSDCommon comorbidTrauma nightmaresSleep disturbancesEffective treatmentGeneral populationPrazosinCurrent diagnosisPatientsSymptoms
2008
Alcohol Detoxification and Relapse Prevention Using Valproic Acid Versus Gabapentin in Alcohol-dependent Patients
Trevisan L, Ralevski E, Keegan K, Oville A, Vuppalapati D, Gonzalez G, Limoncelli D, Petrakis I. Alcohol Detoxification and Relapse Prevention Using Valproic Acid Versus Gabapentin in Alcohol-dependent Patients. Addictive Disorders & Their Treatment 2008, 7: 119-128. DOI: 10.1097/adt.0b013e31812e6a3c.Peer-Reviewed Original ResearchAlcohol withdrawalDays of treatmentSleep disturbancesAlcohol detoxificationModerate withdrawalValproic acidAcute alcohol withdrawalPlacebo-controlled trialMild withdrawal symptomsDoses of benzodiazepinesPrevention of relapseAlcohol-dependent patientsSymptoms of depressionPhysiologic withdrawalPostwithdrawal periodSupportive treatmentAcute symptomsBenzodiazepine medicationWithdrawal symptomsAcute withdrawalPsychiatric symptomsMale veteransClinical importancePsychiatric distressRelapse prevention