2021
Collagen type VI-α1 and 2 repress the proliferation, migration and invasion of bladder cancer cells
Piao X, Hwang B, Jeong P, Byun Y, Kang H, Seo S, Kim W, Lee J, Ha Y, Lee Y, Kim I, Choi Y, Cha E, Moon S, Yun S, Kim W. Collagen type VI-α1 and 2 repress the proliferation, migration and invasion of bladder cancer cells. International Journal Of Oncology 2021, 59: 37. PMID: 33982770, DOI: 10.3892/ijo.2021.5217.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCell Line, TumorCell MovementCell ProliferationCollagen Type VIG1 Phase Cell Cycle CheckpointsGene Expression Regulation, NeoplasticHumansMiddle AgedP38 Mitogen-Activated Protein KinasesPhosphorylationProto-Oncogene Proteins c-aktSignal TransductionTranscription FactorsUrinary Bladder NeoplasmsConceptsNon-muscle invasive BCaExtracellular matrixMRNA expressionEJ cellsBladder cancer microenvironmentTissue samplesHeterogeneous tumor cell populationsCell cycle arrestReverse transcription-quantitative PCRTumor-suppressive effectsBladder cancer cellsP38 MAPK phosphorylationTranscription-quantitative PCRCollagen typesRisk stratificationInvasive BCaTumor infiltrationTumor cell populationBCa pathogenesisMMP-9MAPK phosphorylationAkt phosphorylationCycle arrestNormal controlsMatrix metalloproteinase
2019
A novel tumor suppressing gene, ARHGAP9, is an independent prognostic biomarker for bladder cancer
Piao X, Jeong P, Yan C, Kim Y, Byun Y, Xu Y, Kang H, Seo S, Kim W, Lee J, Kim I, Moon S, Choi Y, Cha E, Yun S, Kim W. A novel tumor suppressing gene, ARHGAP9, is an independent prognostic biomarker for bladder cancer. Oncology Letters 2019, 19: 476-486. PMID: 31897161, PMCID: PMC6924059, DOI: 10.3892/ol.2019.11123.Peer-Reviewed Original ResearchNon-muscle invasive BCMuscle-invasive BCIndependent prognostic biomarkerInvasive BCPrognostic biomarkerProlonged recurrence-free survivalCancer-specific survivalCancer-specific deathRecurrence-free survivalTissues of patientsBC tissue samplesExpression of mRNAVital clinical significanceMIBC patientsBC prognosisPoor prognosisBladder cancerClinical significanceCancer tumorigenesisUseful markerLow expressionPatientsNovel tumorHigh expressionTissue samples