Featured Publications
Cost-Effectiveness of Aspirin for Extended Venous Thromboembolism Prophylaxis After Major Surgery for Inflammatory Bowel Disease
Leeds IL, Sklow B, Gorgun E, Liska D, Lightner AL, Hull TL, Steele SR, Holubar SD. Cost-Effectiveness of Aspirin for Extended Venous Thromboembolism Prophylaxis After Major Surgery for Inflammatory Bowel Disease. Journal Of Gastrointestinal Surgery 2022, 26: 1275-1285. PMID: 35277799, DOI: 10.1007/s11605-022-05287-z.Peer-Reviewed Original ResearchConceptsInflammatory bowel disease surgeryLow-dose aspirinQuality-adjusted life yearsThromboembolism prophylaxisDisease surgeryUnfavorable incremental cost-effectiveness ratiosLife yearsExtended venous thromboembolism prophylaxisPost-discharge event ratePocket costsIncremental cost-effectiveness ratioVenous thromboembolism prophylaxisEfficacy of aspirinInflammatory bowel diseaseMedian hospital costsMonte Carlo probabilistic sensitivity analysisCost-effectiveness ratioProbabilistic sensitivity analysesDecision analysis modelEnoxaparin regimenThromboembolism ratesVenous thromboembolismBowel diseaseColorectal surgeryCase patients
2024
When less is more—3-day vs 7-day selective decontamination of the digestive tract before colorectal surgery
Leeds I, Goffredo P. When less is more—3-day vs 7-day selective decontamination of the digestive tract before colorectal surgery. Journal Of Gastrointestinal Surgery 2024, 28: 1960-1961. PMID: 39265775, DOI: 10.1016/j.gassur.2024.09.005.Peer-Reviewed Original ResearchColorectal surgeryFor whom the bell tolls: assessing the incremental costs associated with failure to rescue after elective colorectal surgery
Schultz K, Moore M, Pantel H, Mongiu A, Reddy V, Schneider E, Leeds I. For whom the bell tolls: assessing the incremental costs associated with failure to rescue after elective colorectal surgery. Journal Of Gastrointestinal Surgery 2024, 28: 1812-1818. PMID: 39181234, DOI: 10.1016/j.gassur.2024.08.019.Peer-Reviewed Original ResearchFailure-to-rescueMedian total hospital costTotal hospital costsColorectal surgeryNational Inpatient SampleUneventful recoveryRetrospective study of adult patientsFailure-to-rescue patientsAssociated with increased healthcare costsStudy of adult patientsElective colorectal resectionHospital costsElective colorectal surgeryNationally representative cohortColorectal resectionElective colectomyPostoperative complicationsRetrospective studyAdult patientsRescue attemptsMedical futilityElective surgeryRepresentative cohortHealthcare costsPrimary outcomeEAES/SAGES evidence-based recommendations and expert consensus on optimization of perioperative care in older adults
Keller D, Curtis N, Burt H, Ammirati C, Collings A, Polk H, Carrano F, Antoniou S, Hanna N, Piotet L, Hill S, Cuijpers A, Tejedor P, Milone M, Andriopoulou E, Kontovounisios C, Leeds I, Awad Z, Barber M, Al-Mansour M, Nassif G, West M, Pryor A, Carli F, Demartines N, Bouvy N, Passera R, Arezzo A, Francis N. EAES/SAGES evidence-based recommendations and expert consensus on optimization of perioperative care in older adults. Surgical Endoscopy 2024, 38: 4104-4126. PMID: 38942944, PMCID: PMC11289045, DOI: 10.1007/s00464-024-10977-7.Peer-Reviewed Original ResearchEvidence-based recommendationsMinimally invasive surgeryOlder adultsOlder adult patientsAbdominal surgeryColorectal surgeryPerioperative carePerioperative care of older adultsAdult patientsCare of older adultsCorrection of anemiaOptimization of perioperative careInfluence surgical outcomesCertainty of evidenceCessation of smokingEvidence synthesisExpert opinionEvidence gapsSurgical outcomesPoor outcomeFunctional capacityERAS programOlder patientsPrehabilitationMeta-analyses
2023
More problems, more money: Identifying and predicting high-cost rescue after colorectal surgery
Leeds I, Moore M, Schultz K, Canner J, Pantel H, Mongiu A, Reddy V, Schneider E. More problems, more money: Identifying and predicting high-cost rescue after colorectal surgery. Surgery Open Science 2023, 16: 148-154. PMID: 38026825, PMCID: PMC10656212, DOI: 10.1016/j.sopen.2023.10.007.Peer-Reviewed Original ResearchColorectal surgeryElective surgeryMedian total inpatient costsAdditional major proceduresElective colorectal surgeryPreoperative clinical predictorsCongestive heart failureGreater healthcare utilizationMultivariable Poisson regressionNational Inpatient SampleTotal inpatient costsElective colectomyCost-conscious careAdult patientsUneventful recoveryClinical predictorsHeart failureHealthcare utilizationInpatient costsSecondary proceduresInpatient SampleHealthcare costsMedian increaseSurgeryPatients
2019
Does Perceived Resident Operative Autonomy Impact Patient Outcomes?
Fieber JH, Bailey EA, Wirtalla C, Johnson AP, Leeds IL, Medbery RL, Ahuja V, VanderMeer T, Wick EC, Irojah B, Kelz RR. Does Perceived Resident Operative Autonomy Impact Patient Outcomes? Journal Of Surgical Education 2019, 76: e182-e188. PMID: 31377204, DOI: 10.1016/j.jsurg.2019.06.006.Peer-Reviewed Original ResearchConceptsGeneral surgery training programsColorectal resectionSurgery serviceSurgery training programsPatient outcomesTrainee autonomyProspective multi-institutional studyColorectal surgery serviceOpen partial colectomyPrior abdominal surgeryRate of readmissionPatients' clinical outcomesPost-graduate year 3Multi-institutional studyImpact patient outcomesMixed effects regression modelsLower ratesAnesthesiologists classificationSeparate mixed-effects regression modelsColorectal surgeryPrimary outcomeSecondary outcomesAbdominal surgerySerious morbidityClinical outcomes
2018
Process measures facilitate maturation of pediatric enhanced recovery protocols
Leeds IL, Ladd MR, Sundel MH, Fannon ML, George JA, Boss EF, Jelin EB. Process measures facilitate maturation of pediatric enhanced recovery protocols. Journal Of Pediatric Surgery 2018, 53: 2266-2272. PMID: 29801659, PMCID: PMC8710141, DOI: 10.1016/j.jpedsurg.2018.04.037.Peer-Reviewed Original ResearchConceptsProcess measuresProcess measure adherenceRecovery protocolEnhanced recovery protocolQuality improvement databaseImplementation groupPediatric colorectal surgeryRegional anesthesia techniquesPediatric ColorectalPostoperative complicationsPreoperative medicationsColorectal surgeryPathway patientsSurgical patientsSurgery pathwayPreoperative educationAnesthesia techniquesPatient outcomesOutcome measuresMeasure adherencePatientsLevel IIITreatment studiesComplicationsAdherence
2017
Quantification of Resident Work in Colorectal Surgery
Bailey EA, Johnson AP, Leeds IL, Medbery RL, Ahuja V, VanderMeer T, Wick EC, Irojah B, Kelz RR. Quantification of Resident Work in Colorectal Surgery. Journal Of Surgical Education 2017, 75: 564-572. PMID: 28986275, DOI: 10.1016/j.jsurg.2017.09.001.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdultClinical CompetenceColorectal SurgeryEducation, Medical, GraduateFemaleHumansInternship and ResidencyInterprofessional RelationsLogistic ModelsMaleMultivariate AnalysisOperating RoomsProfessional AutonomyProspective StudiesSurveys and QuestionnairesUnited StatesConceptsSurgery serviceProspective multi-institutional studyColorectal surgery serviceDay of surgeryGeneral surgery serviceGeneral surgery residency programsMulti-institutional studyAcademic medical centerColorectal resectionColorectal surgerySurgery residency programsFascial closureSkin closureMedical CenterSurvey toolNovel survey toolResponse rateIndependent training programsOperating roomStudy periodSurgeonsSurgeryResidency programsDegree of involvementResidents' work