2021
Chapter 12 Innate immunity in SLE pathogenesis
Kang I. Chapter 12 Innate immunity in SLE pathogenesis. 2021, 181-188. DOI: 10.1016/b978-0-12-820583-9.00025-7.Peer-Reviewed Original ResearchDanger-associated molecular patternsSystemic lupus erythematosusInnate immune cellsToll-like receptorsPattern recognition receptorsDendritic cellsSelf-nucleic acidsImmune cellsGermline-encoded pattern recognition receptorsMultiple inflammatory pathwaysMolecular patternsNuclear factor kappa BAntigen-presenting cellsArray of cytokinesFactor kappa BPathogen-associated molecular patternsCell-intrinsic alterationsLupus erythematosusSLE pathogenesisInflammatory pathwaysInflammatory eventsInterferon regulatory factorIntrinsic alterationsKappa BInnate immunity
2020
Advances in Disease Mechanisms and Translational Technologies: Clinicopathologic Significance of Inflammasome Activation in Autoimmune Diseases
Kahlenberg JM, Kang I. Advances in Disease Mechanisms and Translational Technologies: Clinicopathologic Significance of Inflammasome Activation in Autoimmune Diseases. Arthritis & Rheumatology 2020, 72: 386-395. PMID: 31562704, PMCID: PMC7050400, DOI: 10.1002/art.41127.Peer-Reviewed Original ResearchConceptsPattern recognition receptorsInflammasome activationRheumatic diseasesAutoimmune diseasesIL-18IL-1βClinicopathologic significanceProcaspase-1Damage-associated molecular patternsSystemic lupus erythematosusAdaptive immune pathwaysCrystal-induced arthropathiesCytokines IL-1βDevelopment of inflammationLocal inflammatory responseHost immune responsePrimary target organActive IL-1βActive caspase-1Inflammatory damageLupus erythematosusImmune toleranceRheumatoid arthritisSjögren's syndromePathogenic role