2019
Endocannabinoid System Alterations in Posttraumatic Stress Disorder: A Review of Developmental and Accumulative Effects of Trauma
Nia A, Bender R, Harpaz-Rotem I. Endocannabinoid System Alterations in Posttraumatic Stress Disorder: A Review of Developmental and Accumulative Effects of Trauma. Chronic Stress 2019, 3: 2470547019864096. PMID: 31660473, PMCID: PMC6816276, DOI: 10.1177/2470547019864096.Peer-Reviewed Original ResearchEndocannabinoid system alterationsEndocannabinoid systemSystem alterationsEndocannabinoid ligandsProlonged stressPosttraumatic stress disorderImportant sex differencesClinical studiesPsychiatric symptomsCannabinoid receptorsHuman studiesChronic stressStress disorderTraumaDecreased levelsDevelopmental ageSex differencesCurrent literatureReceptorsAlterationsAccumulative effectReviewSymptomsLevels
2017
Combat Exposure Severity Is Associated With Reduced Cortical Thickness in Combat Veterans: A Preliminary Report
Averill LA, Abdallah CG, Pietrzak RH, Averill CL, Southwick SM, Krystal JH, Harpaz-Rotem I. Combat Exposure Severity Is Associated With Reduced Cortical Thickness in Combat Veterans: A Preliminary Report. Chronic Stress 2017, 1: 2470547017724714. PMID: 28845475, PMCID: PMC5568834, DOI: 10.1177/2470547017724714.Peer-Reviewed Original ResearchCombat exposure severityCortical thicknessCombat exposureEarly life trauma exposureExposure severityEarly life stress exposureRostral middle frontal regionsLife stress exposureNon-PTSD groupEarly life stressStructural magnetic resonanceCombat-exposed veteransChildhood Trauma QuestionnaireCombat-exposed controlsCombat Exposure ScaleCortical thinningLeft superior temporalMiddle frontal regionsNegative correlationNeural biomarkersTreatment targetsNeural integritySuperior temporalPTSD psychopathologyChronic stress