2023
Systematic review and meta-analysis of the genetics of peripheral arterial disease
Ochoa Chaar C, Kim T, Alameddine D, DeWan A, Guzman R, Dardik A, Grossetta Nardini H, Wallach J, Kullo I, Murray M. Systematic review and meta-analysis of the genetics of peripheral arterial disease. JVS Vascular Science 2023, 5: 100133. PMID: 38314202, PMCID: PMC10832467, DOI: 10.1016/j.jvssci.2023.100133.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGenome-wide association studiesDNA variantsWide association studyRecent genome-wide association studiesSmall candidate gene studiesCandidate gene studiesGWAS studiesCandidate genesAssociation studiesGene studiesGenetic researchGeneticsOnly variantVariantsHepatic lipaseGenesProgressionSignificant variation
2021
Evidence synthesis papers would benefit from segmented peer review
Nyhan K, Nardini H. Evidence synthesis papers would benefit from segmented peer review. Translational Oncology 2021, 14: 101060. PMID: 33706230, PMCID: PMC7944096, DOI: 10.1016/j.tranon.2021.101060.Commentaries, Editorials and Letters
2020
Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes
Shen LL, Ahluwalia A, Sun M, Young BK, Nardini H, Del Priore LV. Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes. British Journal Of Ophthalmology 2020, 105: 271-278. PMID: 32471821, PMCID: PMC7704705, DOI: 10.1136/bjophthalmol-2020-316028.Peer-Reviewed Original ResearchConceptsBest-corrected visual acuityLong-term natural historyHorizontal translation factorPrimary endpointVisual acuityNatural historyCommon primary endpointBCVA declineYounger patientsUntreated eyesFuture trialsTreatment trialsAge 39Transition ageSystematic reviewFunction of ageIndividual eyesChoroideremiaAgeEndpointSole endpointEyesPatientsAcuityDisease biomarkersProgression of Unifocal versus Multifocal Geographic Atrophy in Age-Related Macular Degeneration A Systematic Review and Meta-analysis
Shen LL, Sun M, Grossetta Nardini HK, Del Priore LV. Progression of Unifocal versus Multifocal Geographic Atrophy in Age-Related Macular Degeneration A Systematic Review and Meta-analysis. Ophthalmology Retina 2020, 4: 899-910. PMID: 32423772, PMCID: PMC7483721, DOI: 10.1016/j.oret.2020.03.020.Peer-Reviewed Original ResearchConceptsMultifocal geographic atrophyGeographic atrophyMacular Degeneration A Systematic ReviewNonexudative age-related macular degenerationAge-related macular degenerationHorizontal translation factorPrognosis Studies toolSignificant prognostic factorsA Systematic ReviewColor fundus photographyGA growth rateMultifocal groupPrognostic factorsFundus autofluorescenceGA patientsFundus photographyEgger's testMacular degenerationStudy qualityFunnel plotSystematic reviewMeta-AnalysisPublication biasGA lesionsLesion perimeterLong-term Natural History of Atrophy in Eyes with Choroideremia—A Systematic Review and Meta-analysis of Individual-Level Data
Shen LL, Ahluwalia A, Sun M, Young BK, Grossetta Nardini HK, Del Priore LV. Long-term Natural History of Atrophy in Eyes with Choroideremia—A Systematic Review and Meta-analysis of Individual-Level Data. Ophthalmology Retina 2020, 4: 840-852. PMID: 32362554, PMCID: PMC7415675, DOI: 10.1016/j.oret.2020.03.003.Peer-Reviewed Original ResearchConceptsResidual retinal pigment epitheliumLong-term natural historyHorizontal translation factorFundus autofluorescenceRPE areaNatural historyUntreated eyesSystematic reviewPrognosis Studies toolRisk of biasRetinal pigment epitheliumLog-transformed areaAnatomic endpointsPatient ageRPE changesTreatment trialsDisease progressionAnatomic measuresPigment epitheliumMeta-AnalysisLiterature databasesIndividual eyesCross-sectional dataChoroideremiaAtrophyUpdating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses
Wallach JD, Wang K, Zhang AD, Cheng D, Grossetta Nardini HK, Lin H, Bracken MB, Desai M, Krumholz HM, Ross JS. Updating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses. The BMJ 2020, 368: l7078. PMID: 32024657, PMCID: PMC7190063, DOI: 10.1136/bmj.l7078.Peer-Reviewed Original ResearchConceptsIndividual patient-level dataCardiovascular related deathsCardiovascular riskMyocardial infarctionRelated deathsSummary-level dataHeart failureOdds ratioSystematic reviewIncreased cardiovascular riskMore myocardial infarctionsHeart failure eventsCochrane Central RegistryAcute myocardial infarctionMyocardial infarction eventsPatient-level dataRandom-effects modelWeb of ScienceAnalysis of trialsEligible trialsComposite outcomeAdverse eventsContinuity correctionControlled TrialsRosiglitazone treatmentTopographic Variation of the Growth Rate of Geographic Atrophy in Nonexudative Age-Related Macular Degeneration: A Systematic Review and Meta-analysis
Shen LL, Sun M, Khetpal S, Nardini H, Del Priore LV. Topographic Variation of the Growth Rate of Geographic Atrophy in Nonexudative Age-Related Macular Degeneration: A Systematic Review and Meta-analysis. Investigative Ophthalmology & Visual Science 2020, 61: 2. PMID: 31995152, PMCID: PMC7205189, DOI: 10.1167/iovs.61.1.2.Peer-Reviewed Original Research
2019
Librarians as methodological peer reviewers for systematic reviews: results of an online survey
Grossetta Nardini HK, Batten J, Funaro MC, Garcia-Milian R, Nyhan K, Spak JM, Wang L, Glover JG. Librarians as methodological peer reviewers for systematic reviews: results of an online survey. Research Integrity And Peer Review 2019, 4: 23. PMID: 31798974, PMCID: PMC6882225, DOI: 10.1186/s41073-019-0083-5.Peer-Reviewed Original ResearchRECLASSIFICATION OF FUNDUS AUTOFLUORESCENCE PATTERNS SURROUNDING GEOGRAPHIC ATROPHY BASED ON PROGRESSION RATE
Shen LL, Liu F, Nardini HG, Del Priore LV. RECLASSIFICATION OF FUNDUS AUTOFLUORESCENCE PATTERNS SURROUNDING GEOGRAPHIC ATROPHY BASED ON PROGRESSION RATE. Retina 2019, Publish Ahead of Print: &na;. PMID: 30829988, DOI: 10.1097/iae.0000000000002480.Peer-Reviewed Original ResearchConceptsGA progression ratesFAF patternsGeographic atrophyProgression rateHorizontal translation factorFundus autofluorescence patternsDifferent entry timesLesion progression ratesFundus autofluorescenceCochrane LibraryClinical trialsAutofluorescence patternsGroup 2Group 1Group 3Group 4Natural historyAtrophyGroupRadius growth rateYearsEMBASEMEDLINEPubMedNatural History of Autosomal Recessive Stargardt Disease in Untreated Eyes A Systematic Review and Meta-analysis of Study- and Individual-Level Data
Shen LL, Sun M, Grossetta Nardini HK, Del Priore LV. Natural History of Autosomal Recessive Stargardt Disease in Untreated Eyes A Systematic Review and Meta-analysis of Study- and Individual-Level Data. Ophthalmology 2019, 126: 1288-1296. PMID: 31227323, DOI: 10.1016/j.ophtha.2019.05.015.Peer-Reviewed Original ResearchConceptsBaseline lesion sizeHorizontal translation factorAutosomal recessive Stargardt diseaseRecessive Stargardt diseaseLog-transformed areaLesion sizeUntreated eyesAtrophic lesionsStargardt diseaseSystematic reviewNatural historyOnset of symptomsNewcastle-Ottawa ScaleRisk of biasReliable outcome measuresIndividual-level dataAtrophy progressionFundus autofluorescenceInclusion criteriaOutcome measuresMeta-AnalysisLesion onsetProgression patternsLiterature databasesLesions
2018
Fellow Eye Status Is a Biomarker for the Progression Rate of Geographic Atrophy A Systematic Review and Meta-analysis
Shen LL, Liu F, Grossetta Nardini H, Del Priore LV. Fellow Eye Status Is a Biomarker for the Progression Rate of Geographic Atrophy A Systematic Review and Meta-analysis. Ophthalmology Retina 2018, 3: 305-315. PMID: 31014681, DOI: 10.1016/j.oret.2018.11.013.Peer-Reviewed Original ResearchConceptsAge-related macular degenerationFellow eye statusFellow eyesChoroidal neovascularizationGeographic atrophyProgression rateEye statusPrimary eyesSystematic reviewAdvanced age-related macular degenerationGA enlargement rateHorizontal translation factorA Systematic ReviewGA progression ratesNewcastle-Ottawa ScalePrior clinical studiesDifferent entry timesGA patientsCochrane LibraryClinical trialsClinical studiesEgger's testMacular degenerationStudy qualityBegg's testSubstance Use in Medical Trainees: Current Problems and Future Directions
Horien C, Athar W, Grossetta Nardini HK, Grunschel B. Substance Use in Medical Trainees: Current Problems and Future Directions. Academic Psychiatry 2018, 42: 438-439. PMID: 29511970, PMCID: PMC5943170, DOI: 10.1007/s40596-018-0898-2.Peer-Reviewed Original ResearchQuality Assurance Practices in Obstetric Care
Lundsberg LS, Lee HC, Dueñas GV, Gregory KD, Nardini H, Pettker CM, Illuzzi JL, Xu X. Quality Assurance Practices in Obstetric Care. Obstetrics And Gynecology 2018, 131: 214-223. PMID: 29324608, PMCID: PMC7020098, DOI: 10.1097/aog.0000000000002437.Peer-Reviewed Original ResearchConceptsAbnormal fetal heart rateEvidence-supported practicesFetal heart rateObstetric careHeart rateFrequent simulationLabor arrestCesarean deliveryPostpartum hemorrhageSignificant morbidityObstetric hospitalPerinatal careShoulder dystociaAppropriate statistical testsHospital practiceHospitalBivariate analysisTeaching statusMost hospitalsCareEclampsiaPrivate nonprofit hospitalsInterprofessional simulationStatewide surveyBroad spectrum
2017
Growth and Rupture Risk of Small Unruptured Intracranial Aneurysms: A Systematic Review.
Malhotra A, Wu X, Forman HP, Grossetta Nardini HK, Matouk CC, Gandhi D, Moore C, Sanelli P. Growth and Rupture Risk of Small Unruptured Intracranial Aneurysms: A Systematic Review. Annals Of Internal Medicine 2017, 167: 26-33. PMID: 28586893, DOI: 10.7326/m17-0246.Peer-Reviewed Original ResearchSystematic review of community-engaged research in ophthalmology
Nwanyanwu KH, Nardini H, Shaughness G, Nunez-Smith M, Newman-Casey PA. Systematic review of community-engaged research in ophthalmology. Expert Review Of Ophthalmology 2017, 12: 233-241. PMID: 29333193, PMCID: PMC5759339, DOI: 10.1080/17469899.2017.1311787.Peer-Reviewed Original ResearchCommunity-engaged researchOvid EmbaseCochrane LibraryCommunity-based participatory researchMedical Subject HeadingsOvid MEDLINEEye diseaseNLM PubMedHealth outcomesSystematic reviewHealth disparitiesVision disordersComprehensive searchOphthalmic researchRelevant studiesOphthalmologyAdditional referencesFull textParticipatory researchExpert consultationOutcomesSubject headingsUnique referencesField of medicineCommunity engagement
2016
Utility of MRI for cervical spine clearance after blunt traumatic injury: a meta-analysis
Malhotra A, Wu X, Kalra VB, Nardini HK, Liu R, Abbed KM, Forman HP. Utility of MRI for cervical spine clearance after blunt traumatic injury: a meta-analysis. European Radiology 2016, 27: 1148-1160. PMID: 27334017, DOI: 10.1007/s00330-016-4426-z.Peer-Reviewed Original ResearchConceptsPositive finding rateUnstable injuriesUtility of MRIAlert patientsPooled incidenceCervical spine trauma patientsCervical spine clearanceBlunt traumatic injurySpine trauma patientsMajor medical databasesFurther studiesCS clearanceSpine clearanceTrauma patientsAwake patientsNegative CTTraumatic injuryPatientsUnique citationsSystematic reviewInjuryPositive findingsIncidenceMRIHigh false positive rate
2014
Micro-costing studies in the health and medical literature: protocol for a systematic review
Xu X, Grossetta Nardini HK, Ruger JP. Micro-costing studies in the health and medical literature: protocol for a systematic review. Systematic Reviews 2014, 3: 47. PMID: 24887208, PMCID: PMC4036677, DOI: 10.1186/2046-4053-3-47.Peer-Reviewed Original ResearchConceptsMicro-costing studiesMicro-costing studyNational Health Service Economic Evaluation DatabaseHealth economic studiesEconomic Evaluation DatabaseMicro-costing methodologyLong runEconomic evaluationEconomic studiesCost estimation methodsTrue costEconomic costsEvaluation DatabaseResource allocation
2013
Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome
Nayeri UA, West AB, Nardini H, Copel JA, Sfakianaki AK. Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound In Obstetrics And Gynecology 2013, 41: 366-374. PMID: 23239538, DOI: 10.1002/uog.12359.Peer-Reviewed Original ResearchConceptsPlacental mesenchymal dysplasiaHuman chorionic gonadotropinPregnancy outcomesMolar pregnancyFetal anomaliesPreterm laborBeckwith-Wiedemann syndromeMesenchymal dysplasiaSonographic featuresInclusion criteriaCase of PMDDiagnosis of PMDSystematic reviewNormal neonatal outcomePlacental vascular anomalySerial growth scansThird-trimester assessmentAdverse pregnancy outcomesSubsequent pregnancy outcomeIntrauterine fetal deathCommon sonographic featuresIntrauterine growth restrictionGestational trophoblastic diseasePlacental lakesNeonatal outcomes
1998
Internet access in the libraries of the National Network of Libraries of Medicine.
Lyon BJ, Stavri PZ, Hochstein DC, Nardini HG. Internet access in the libraries of the National Network of Libraries of Medicine. Bulletin Of The Medical Library Association 1998, 86: 486-90. PMID: 9803289, PMCID: PMC226439.Peer-Reviewed Original Research
1996
The Internet: a new instrument in a virtual "doctor's bag".
Glover J, Grossetta Nardini HK. The Internet: a new instrument in a virtual "doctor's bag". Connecticut Medicine 1996, 60: 413-22. PMID: 8758659.Peer-Reviewed Educational Materials