2000
Relapse and cure rates of prostate cancer patients after radical prostatectomy and 5 years of follow-up
Vassilikos E, Yu H, Trachtenberg J, Nam R, Narod S, Bromberg I, Diamandis E. Relapse and cure rates of prostate cancer patients after radical prostatectomy and 5 years of follow-up. Clinical Biochemistry 2000, 33: 115-123. PMID: 10751589, DOI: 10.1016/s0009-9120(99)00099-5.Peer-Reviewed Original ResearchMeSH KeywordsAgedDisease-Free SurvivalFluorescent Antibody TechniqueFollow-Up StudiesHumansMaleMiddle AgedNeoplasm InvasivenessNeoplasm StagingProportional Hazards ModelsProstatectomyProstate-Specific AntigenProstatic NeoplasmsRecurrenceRegression AnalysisReproducibility of ResultsSensitivity and SpecificityTime FactorsTreatment OutcomeConceptsProstate cancer patientsRadical prostatectomySerum PSACancer patientsPSA assaysUltrasensitive prostate specific antigenPre-operative PSAGroup of patientsSerial serum samplesEarly therapeutic interventionSeminal vesicle invasionSurgical margin positivityProstate-specific antigenRegular PSAUltrasensitive PSAPSA increaseMargin positivityClinical stageGleason scorePrognostic indicatorCapsular invasionTissue involvementTumor volumePatientsFast relapse
1999
Prostate specific antigen molecular forms in breast cyst fluid and serum of women with fibrocystic breast disease
Borchert G, Yu H, Tomlinson G, Giai M, Roagna R, Ponzone R, Sgro L, Diamandis E. Prostate specific antigen molecular forms in breast cyst fluid and serum of women with fibrocystic breast disease. Journal Of Clinical Laboratory Analysis 1999, 13: 75-81. PMID: 10102136, PMCID: PMC6807928, DOI: 10.1002/(sici)1098-2825(1999)13:2<75::aid-jcla6>3.0.co;2-f.Peer-Reviewed Original ResearchConceptsBreast cyst fluidBreast cyst fluid samplesFibrocystic breast diseaseTotal PSACyst fluidCyst fluid samplesSerum PSAFree PSABreast diseaseHigher total PSASerum of womenTotal serum PSATotal PSA concentrationsFluid samplesType II cystsPredominant molecular formApocrine cystsPatient agePSA ratioBreast feedMultiple cystsInverse associationChi-square analysisFemale serumPSA concentration
1997
NONPROSTATIC SOURCES OF PROSTATE-SPECIFIC ANTIGEN
Diamandis E, Yu H. NONPROSTATIC SOURCES OF PROSTATE-SPECIFIC ANTIGEN. Urologic Clinics Of North America 1997, 24: 275-282. PMID: 9126224, DOI: 10.1016/s0094-0143(05)70373-6.Peer-Reviewed Original ResearchConceptsNonprostatic tissuesProstate-specific antigenBreast nipple aspirate fluidBreast cancer risk assessmentPSA gene expressionBreast cancer cytosolsHigher PSA concentrationsBreast cancer prognosisRegulation of PSAPotential clinical utilityCancer risk assessmentMicrograms/LNonprostatic sourcesPSA regulationAndrogen excessSerum PSAMicrograms/L.Breast secretionsAspirate fluidSeminal plasmaPSA productionPSA-ACT complexClinical utilityCancer cytosolsProstatic tissue
1995
Quantification of creatine kinase BB isoenzyme in tumor cytosols and serum with an ultrasensitive time-resolved immunofluorometric technique
Zarghami N, Yu H, Diamandis E, Sutherland D. Quantification of creatine kinase BB isoenzyme in tumor cytosols and serum with an ultrasensitive time-resolved immunofluorometric technique. Clinical Biochemistry 1995, 28: 243-253. PMID: 7554242, DOI: 10.1016/0009-9120(95)00010-7.Peer-Reviewed Original ResearchConceptsCK-BB levelsBreast tumor cytosolsCreatine kinase BBCK-BBProstate cancerTumor cytosolsCancer patientsEstrogen sensitivityHealthy subjectsSerum CK-BB levelsActive prostate cancerSensitive immunofluorometric procedurePost-radical prostatectomyProstate cancer patientsSerum CK-BBCK-BB isoenzymeSteroid hormone receptorsSerum PSAProgesterone receptorRadical prostatectomyBreast cancerMale volunteersHealthy volunteersPatientsBreast tumors