Soluble levels of CD27 and CD30 are associated with risk of non‐Hodgkin lymphoma in three Chinese prospective cohorts
Bassig BA, Shu XO, Koh WP, Gao YT, Purdue MP, Butler LM, Adams-Haduch J, Xiang YB, Kemp TJ, Wang R, Pinto LA, Zheng T, Ji BT, Hosgood HD, Hu W, Yang G, Zhang H, Chow WH, Kim C, Seow WJ, Zheng W, Yuan JM, Lan Q, Rothman N. Soluble levels of CD27 and CD30 are associated with risk of non‐Hodgkin lymphoma in three Chinese prospective cohorts. International Journal Of Cancer 2015, 137: 2688-2695. PMID: 26095604, PMCID: PMC4898881, DOI: 10.1002/ijc.29637.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAsia, EasternAsian PeopleB-LymphocytesBiomarkers, TumorCase-Control StudiesFemaleHumansKi-1 AntigenLymphocyte ActivationLymphoma, Non-HodgkinMaleMiddle AgedProspective StudiesRiskRisk FactorsTumor Necrosis Factor Receptor Superfamily, Member 7ConceptsNon-Hodgkin lymphomaB cell activationProspective studyNHL riskWestern populationsChinese prospective cohortIntermediate endpoint biomarkersCase-control studySoluble CD30Prospective cohortSoluble CD27Fourth quartileBlood drawLowest quartileEndpoint biomarkersNHL casesImportant underlying mechanismChinese menSimilar associationSoluble levelsSCD27SCD30CD30CD27Underlying mechanism