2018
Effect of exposure to second-hand smoke from husbands on biochemical hyperandrogenism, metabolic syndrome and conception rates in women with polycystic ovary syndrome undergoing ovulation induction
Li J, Wu Q, Wu XK, Zhou ZM, Fu P, Chen XH, Yan Y, Wang X, Yang ZW, Li WL, Stener-Victorin E, Legro RS, Ng EH, Zhang H, Mol BWJ, Wang CC, Group F. Effect of exposure to second-hand smoke from husbands on biochemical hyperandrogenism, metabolic syndrome and conception rates in women with polycystic ovary syndrome undergoing ovulation induction. Human Reproduction 2018, 33: 617-625. PMID: 29471520, DOI: 10.1093/humrep/dey027.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeNon-exposed womenSHS exposure statusSHS exposureMetabolic syndromeBiochemical hyperandrogenismObstetric outcomesOvary syndromeOvulation inductionSex hormonesExposure statusHigher serum total testosteroneSecond-hand smoke exposureSTUDY FUNDING/COMPETINGConception rateLower sex hormoneFree androgen indexSerum total testosteroneUterine blood flowLive birth rateNon-exposed groupSecond-hand smokePARTICIPANTS/MATERIALSROLE OF CHANCEAndrogen index
2014
Smoking in infertile women with polycystic ovary syndrome: baseline validation of self-report and effects on phenotype
Legro RS, Chen G, Kunselman AR, Schlaff WD, Diamond MP, Coutifaris C, Carson SA, Steinkampf MP, Carr BR, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Myers ER, Zhang H, Foulds J, Barnhart K, Martino L, Timbers K, Lambe L, DeWire R, Yang H, Bodine C, Mark D, Puscheck E, Ginsburg K, Collins K, Brossoit M, Leach R, Yelian F, Perez M, Buster J, Amato P, Torres M, Dodson W, Gnatuk C, Ober J, Demers L, Heller D, Colon J, Weiss G, Solnica A, Gatlin K, Hahn S, Roark M, Blackwell R, Willis V, Love L, Laychak K, Nazmy M, Stovall D, Evans W, Turner K, Chang J, Malcolm P, Coddington C, Permanente K, Faber K, Hasenleider D, Huang H. Smoking in infertile women with polycystic ovary syndrome: baseline validation of self-report and effects on phenotype. Human Reproduction 2014, 29: 2680-2686. PMID: 25324541, PMCID: PMC4227579, DOI: 10.1093/humrep/deu239.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeSerum cotinine levelsCase-control studySmoking statusInfertility treatmentCotinine levelsPast smokersCurrent smokersOvary syndromeInfertile womenInsulin resistanceFirst-line ovulation induction agentsMulti-center clinical trialOvulation induction agentsWorse insulin resistanceTotal testosterone levelsLive birth rateSecond-hand smokePARTICIPANTS/MATERIALSNational InstituteROLE OF CHANCESelf-reported changesHirsutism scoreSmoking groupRecent smokers