2021
Adoption of New Risk Stratification Technologies Within US Hospital Referral Regions and Association With Prostate Cancer Management
Leapman MS, Wang R, Park HS, Yu JB, Sprenkle PC, Dinan MA, Ma X, Gross CP. Adoption of New Risk Stratification Technologies Within US Hospital Referral Regions and Association With Prostate Cancer Management. JAMA Network Open 2021, 4: e2128646. PMID: 34623406, PMCID: PMC8501394, DOI: 10.1001/jamanetworkopen.2021.28646.Peer-Reviewed Original ResearchConceptsProstate magnetic resonance imagingMagnetic resonance imagingHospital referral regionsProportion of patientsProstate cancerGenomic testingCohort studyReferral regionsRetrospective cohort studyProstate cancer carePatient-level analysisCommercial insurance claimsProstate cancer managementUS hospital referral regionsYears of ageProportion of menPatients 40Definitive treatmentCancer careTesting uptakeHRR levelMAIN OUTCOMECancer managementPatientsRegional uptake
2020
Nationwide patterns of hemorrhagic stroke among patients hospitalized with brain metastases: influence of primary cancer diagnosis and anticoagulation
Lee V, Jairam V, Yu JB, Park HS. Nationwide patterns of hemorrhagic stroke among patients hospitalized with brain metastases: influence of primary cancer diagnosis and anticoagulation. Scientific Reports 2020, 10: 10084. PMID: 32572113, PMCID: PMC7308286, DOI: 10.1038/s41598-020-67316-8.Peer-Reviewed Original ResearchConceptsBrain metastasesLong-term anticoagulationIntracerebral hemorrhageKidney cancerHigh riskUtilization Project Nationwide Inpatient SampleDiagnosis of ICHHospital-related characteristicsRisks of anticoagulationPrimary cancer diagnosisMultivariable logistic regressionNationwide Inpatient SampleLonger lengthDiagnosis of melanomaMann-Whitney UHemorrhagic strokeNeurologic dysfunctionConcurrent diagnosisSignificant morbiditySecondary diagnosisInpatient SampleBaseline differencesDecreased qualityAnticoagulationHealthcare costs
2016
Hospital Volume and Outcomes of Robot-Assisted Lobectomies
Tchouta LN, Park HS, Boffa DJ, Blasberg JD, Detterbeck FC, Kim AW. Hospital Volume and Outcomes of Robot-Assisted Lobectomies. CHEST Journal 2016, 151: 329-339. PMID: 27687847, DOI: 10.1016/j.chest.2016.09.008.Peer-Reviewed Original ResearchMeSH KeywordsAgedCase-Control StudiesCohort StudiesDatabases, FactualFemaleHospital MortalityHospitals, High-VolumeHospitals, Low-VolumeHumansLength of StayLinear ModelsLogistic ModelsLungLung NeoplasmsMaleMiddle AgedMultivariate AnalysisPneumonectomyPostoperative ComplicationsRetrospective StudiesRobotic Surgical ProceduresThoracic Surgery, Video-AssistedTreatment OutcomeConceptsLength of stayLow-volume centersHospital volumeClinical impactHealth care system-related factorsShorter mean LOSUtilization Project National Inpatient Sample databaseVolume/outcome relationshipLong-term clinical impactMean LOSNational Inpatient Sample databaseShorter LOSVideo-assisted thoracoscopic surgeryHospital operative volumeHigh-volume hospitalsIncidence of complicationsHigher hospital volumeThoracoscopic surgery lobectomyAnnual case volumeSystem-related factorsOutcomes of interestLOS outcomesInfectious complicationsInpatient mortalityIndependent predictorsPulmonary dose-volume predictors of radiation pneumonitis following stereotactic body radiation therapy
Harder EM, Park HS, Chen Z, Decker RH. Pulmonary dose-volume predictors of radiation pneumonitis following stereotactic body radiation therapy. Practical Radiation Oncology 2016, 6: e353-e359. PMID: 27156424, DOI: 10.1016/j.prro.2016.01.015.Peer-Reviewed Original ResearchConceptsMean lung doseStereotactic body radiation therapyRisk of gradeRadiation pneumonitisMultivariable logistic regressionBody radiation therapyDosimetric predictorsRadiation therapyMaximum doseLogistic regressionRP rateBest dosimetric predictorCardiac dosimetric parametersDose-volume predictorsPercent of lungVolume of lungGross tumor volumeBackward stepwise eliminationLung V10Lung doseMean doseTotal lungUnivariate analysisPulmonary volumesTumor volume
2015
Postoperative Radiation Therapy Is Associated With Improved Overall Survival in Incompletely Resected Stage II and III Non–Small-Cell Lung Cancer
Wang EH, Corso CD, Rutter CE, Park HS, Chen AB, Kim AW, Wilson LD, Decker RH, Yu JB. Postoperative Radiation Therapy Is Associated With Improved Overall Survival in Incompletely Resected Stage II and III Non–Small-Cell Lung Cancer. Journal Of Clinical Oncology 2015, 33: 2727-2734. PMID: 26101240, DOI: 10.1200/jco.2015.61.1517.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungDatabases, FactualFemaleHumansKaplan-Meier EstimateLogistic ModelsLung NeoplasmsMaleMiddle AgedNeoplasm StagingNeoplasm, ResidualPneumonectomyRadiotherapy DosageRadiotherapy, AdjuvantRadiotherapy, ConformalRadiotherapy, Intensity-ModulatedRegistriesRetrospective StudiesTreatment OutcomeUnited StatesConceptsUse of PORTPostoperative radiotherapyOverall survivalNodal stageStage IIMultivariable analysisPatient populationLung cancerNon-small cell lung cancerOverall American Joint CommitteeNational Cancer Data BaseImproved overall survivalLower nodal stagePostoperative radiation therapyPositive surgical marginsAmerican Joint CommitteeCancer stage IICell lung cancerProportional hazards regressionMultivariable logistic regressionClinicopathologic covariatesChemotherapy receiptPerioperative mortalityOnly patientsSuch patientsThe evolving role of adjuvant radiotherapy for elderly women with early‐stage breast cancer
Rutter CE, Lester-Coll NH, Mancini BR, Corso CD, Park HS, Yeboa DN, Gross CP, Evans SB. The evolving role of adjuvant radiotherapy for elderly women with early‐stage breast cancer. Cancer 2015, 121: 2331-2340. PMID: 25810128, DOI: 10.1002/cncr.29377.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerER-positive early-stage breast cancerRT useElderly patientsLogistic regression analysisBoost radiotherapyAdjuvant radiotherapyBreast cancerLeukemia Group B (CALGB) 9343 trialPositive early-stage breast cancerNational Cancer Data BaseMultivariable logistic regression analysisAvoidance of radiotherapyLocal control benefitNegative resection marginsYear of diagnosisUse of radiotherapyRegression analysisClinicopathologic covariatesRT detailsOlder patientsOverall survivalHypofractionated radiotherapyResection marginsEvidence-based practice
2009
Outcomes From 3144 Adrenalectomies in the United States: Which Matters More, Surgeon Volume or Specialty?
Park HS, Roman SA, Sosa JA. Outcomes From 3144 Adrenalectomies in the United States: Which Matters More, Surgeon Volume or Specialty? JAMA Surgery 2009, 144: 1060-1067. PMID: 19917944, DOI: 10.1001/archsurg.2009.191.Peer-Reviewed Original ResearchMeSH KeywordsAdrenal Gland NeoplasmsAdrenalectomyAdultAgedClinical CompetenceCohort StudiesFemaleFollow-Up StudiesHospital CostsHospital MortalityHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOutcome Assessment, Health CarePractice Patterns, Physicians'ProbabilityRegistriesRetrospective StudiesRisk FactorsSpecializationSurvival RateTreatment OutcomeUnited StatesWorkloadConceptsHigh-volume surgeonsSurgeon volumeHospital volumeMore complicationsGeneral surgeonsUtilization Project Nationwide Inpatient SampleRetrospective cohort analysisNationwide Inpatient SampleLow-volume surgeonsPredictors of costsInpatient hospital costsTotal inpatient hospital costsHospital complicationsHospital lengthAdrenal volumeClinical characteristicsHospital factorsAdrenal diseaseIndependent predictorsLonger LOSPatient ageSurgeon specialtyInpatient SampleHospital costsLaparoscopic expertise