2022
Hypofractionated vs . standard radiotherapy for locally advanced limited-stage small cell lung cancer
Saeed NA, Jin L, Sasse AW, Amini A, Verma V, Lester-Coll NH, Chen PH, Decker RH, Park HS. Hypofractionated vs . standard radiotherapy for locally advanced limited-stage small cell lung cancer. Journal Of Thoracic Disease 2022, 0: 0-0. PMID: 35280466, PMCID: PMC8902118, DOI: 10.21037/jtd-21-1566.Peer-Reviewed Original ResearchLimited stage small cell lung cancerSmall cell lung cancerCell lung cancerOverall survivalStandard radiotherapyLung cancerHypofractionated radiotherapyConcurrent chemotherapyComparable overall survivalMedian overall survivalMultivariable Cox regressionPrimary stage IINational Cancer DatabaseRetrospective cohort studyMultivariable logistic regressionLog-rank testChemotherapy timingCohort studyPatient characteristicsMultivariable analysisCox regressionWhole cohortCancer DatabasePractice patternsChemotherapy
2021
Adoption of consolidative durvalumab among patients with locally advanced non-small cell lung cancer.
Jairam V, Pasha S, Soulos P, Goldberg S, Yu J, Decker R, Gross C, Park H. Adoption of consolidative durvalumab among patients with locally advanced non-small cell lung cancer. Journal Of Clinical Oncology 2021, 39: e20550-e20550. DOI: 10.1200/jco.2021.39.15_suppl.e20550.Peer-Reviewed Original ResearchNon-small cell lung cancerCell lung cancerTumor characteristicsLung cancerFDA approvalConsolidative durvalumabPatient characteristicsUnresectable stage III non-small cell lung cancerStage III non-small cell lung cancerAdvanced non-small cell lung cancerFirst-line platinum-doublet chemotherapyStudy periodFlatiron Health databasePlatinum-doublet chemotherapyGuideline-concordant carePD-L1 statusMultivariable logistic regressionCochran-Armitage testDe-identified databaseChi-square testDefinitive chemoradiationDoublet chemotherapyEligible patientsPACIFIC trialSurgery details
2019
Outcomes following Lower Extremity Amputation in Patients with Diabetes Mellitus and Peripheral Arterial Disease
Pourghaderi P, Yuquimpo KM, Roginski Guetter C, Mansfield L, Park HS. Outcomes following Lower Extremity Amputation in Patients with Diabetes Mellitus and Peripheral Arterial Disease. Annals Of Vascular Surgery 2019, 63: 259-268. PMID: 31626926, DOI: 10.1016/j.avsg.2019.08.084.Peer-Reviewed Original ResearchConceptsPeripheral arterial diseaseLower extremity amputationConcurrent diabetes mellitusDiabetes mellitusArterial diseaseExtremity amputationPresence of PADUtilization Project Nationwide Inpatient SampleICD-9 procedure codesNationwide Inpatient SampleBest practice careAdult patientsPatient characteristicsPostoperative outcomesSuch comorbiditiesAdditional patientsClinical outcomesMultivariable analysisEmergency admissionsMean agePatient morbidityPatient populationInpatient SampleHospital characteristicsHigh incidence
2018
Complementary Medicine, Refusal of Conventional Cancer Therapy, and Survival Among Patients With Curable Cancers
Johnson SB, Park HS, Gross CP, Yu JB. Complementary Medicine, Refusal of Conventional Cancer Therapy, and Survival Among Patients With Curable Cancers. JAMA Oncology 2018, 4: 1375-1381. PMID: 30027204, PMCID: PMC6233773, DOI: 10.1001/jamaoncol.2018.2487.Peer-Reviewed Original ResearchConceptsConventional cancer treatmentsUse of CMOverall survivalComplementary medicineHormone therapyTreatment delayCharlson-Deyo comorbidity scoreCancer treatmentCancer-accredited centersNational Cancer DatabaseCharacteristics of patientsYear of diagnosisRetrospective observational studyConventional cancer therapiesHigh refusal rateRace/ethnicityNonmetastatic breastComorbidity scorePatient characteristicsCurable cancerEntire cohortColorectal cancerCancer DatabaseInsurance typeObservational study
2016
Pretreatment predictors of adjuvant chemoradiation in patients receiving transoral robotic surgery for squamous cell carcinoma of the oropharynx: a case control study
Subramanian HE, Park HS, Barbieri A, Mahajan A, Judson BL, Mehra S, Yarbrough WG, Burtness BA, Husain ZA. Pretreatment predictors of adjuvant chemoradiation in patients receiving transoral robotic surgery for squamous cell carcinoma of the oropharynx: a case control study. Cancers Of The Head & Neck 2016, 1: 7. PMID: 31093337, PMCID: PMC6460847, DOI: 10.1186/s41199-016-0008-7.Peer-Reviewed Original ResearchTransoral robotic surgeryPositive lymph nodesPreoperative patient characteristicsLymph node sizePositive surgical marginsExtracapsular extensionLymph nodesPatient characteristicsSurgical marginsAdjuvant chemoradiationNeck dissectionIndependent predictorsPositive marginsLymph node extracapsular extensionSingle-institution retrospective studyNode sizeLogistic regressionRobotic surgeryNodal extracapsular extensionPreoperative lymph nodeEarly-stage diseaseMajority of patientsSquamous cell carcinomaCase-control studyPrimary oropharyngeal cancer