2021
Association of Epigenetic Age Acceleration With Risk Factors, Survival, and Quality of Life in Patients With Head and Neck Cancer
Xiao C, Miller AH, Peng G, Levine ME, Conneely KN, Zhao H, Eldridge RC, Wommack EC, Jeon S, Higgins KA, Shin DM, Saba NF, Smith AK, Burtness B, Park HS, Irwin ML, Ferrucci LM, Ulrich B, Qian DC, Beitler JJ, Bruner DW. Association of Epigenetic Age Acceleration With Risk Factors, Survival, and Quality of Life in Patients With Head and Neck Cancer. International Journal Of Radiation Oncology • Biology • Physics 2021, 111: 157-167. PMID: 33882281, PMCID: PMC8802868, DOI: 10.1016/j.ijrobp.2021.04.002.Peer-Reviewed Original ResearchConceptsProgression-free survivalBody mass indexQuality of lifeHigher epigenetic age accelerationTreatment-related symptomsOverall survivalEpigenetic age accelerationRadiation therapyRisk factorsClinical characteristicsNeck cancerAge accelerationWorse overall survivalHuman papilloma virusFaster biological agingAdverse eventsDistant metastasisLifestyle factorsMass indexCancer outcomesBlood biomarkersPapilloma virusFunctional assessmentHigher HRPatients
2019
Emergency Department Visits for Opioid Overdoses Among Patients With Cancer
Jairam V, Yang DX, Yu JB, Park HS. Emergency Department Visits for Opioid Overdoses Among Patients With Cancer. Journal Of The National Cancer Institute 2019, 112: 938-943. PMID: 31845985, PMCID: PMC7492769, DOI: 10.1093/jnci/djz233.Peer-Reviewed Original ResearchConceptsOpioid-related ED visitsED visitsEmergency departmentOpioid overdoseComorbid diagnosesUtilization Project Nationwide Emergency Department SampleMultivariable logistic regression analysisNationwide Emergency Department SampleHigh opioid useOpioid-related visitsPrimary disease siteEmergency department visitsEmergency Department SampleLogistic regression analysisSubstance use disordersOpioid useDepartment visitsChronic painMultiple myelomaNeck cancerPrimary diagnosisRisk factorsPatient visitsBaseline differencesOpioid overdosesHead and Neck Cancers
Trifiletti D, Zaorsky N, Park H. Head and Neck Cancers. 2019, 133-196. DOI: 10.1007/978-3-319-96809-4_4.Peer-Reviewed Original Research
2018
Permanent Interstitial Brachytherapy for Previously Irradiated Head and Neck Cancer
Breen W, Kelly J, Park HS, Son Y, Sasaki C, Wilson L, Decker R, Husain ZA. Permanent Interstitial Brachytherapy for Previously Irradiated Head and Neck Cancer. Cureus 2018, 10: e2517. PMID: 29942720, PMCID: PMC6015992, DOI: 10.7759/cureus.2517.Peer-Reviewed Original ResearchNeck cancerExtranodal extensionOverall survivalLocal controlAdverse events grade 3Worse locoregional controlCommon Terminology CriteriaPercent of patientsDisease-free intervalSecond primary cancerImprovement of symptomsRecords of patientsWorse local controlWorse overall survivalPermanent interstitial brachytherapyMucosal recurrenceNeck recurrenceTerminology CriteriaLocoregional controlMedian dosePersistent tumorNeck diseasePrimary cancerRecurrent cancerMucosal disease
2016
Disparities in radiation therapy delivery: current evidence and future directions in head and neck cancer
Park HS, Decker RH. Disparities in radiation therapy delivery: current evidence and future directions in head and neck cancer. Cancers Of The Head & Neck 2016, 1: 5. PMID: 31093335, PMCID: PMC6457146, DOI: 10.1186/s41199-016-0005-x.Peer-Reviewed Original ResearchNeck cancerCurrent evidenceNon-clinical factorsDelivery of surgerySystemic therapyTreatment disparitiesRadiation therapyRadiation therapy deliveryClinical decisionCertain subpopulationsCancerTherapySocioeconomic statusTherapy deliveryPatientsMore researchHypothesized mechanismsDisparitiesHeadFuture directionsDeliverySurgery