2021
Effect of prior thoracic radiotherapy on prognosis in relapsed small cell lung cancer patients treated with anlotinib: a subgroup analysis of the ALTER 1202 trial
Liu Y, Cheng Y, Li K, Shi J, Liu Y, Wu L, Han B, Chen G, He J, Wang J, Qin H, Li X, Hamaji M, Park HS. Effect of prior thoracic radiotherapy on prognosis in relapsed small cell lung cancer patients treated with anlotinib: a subgroup analysis of the ALTER 1202 trial. Translational Lung Cancer Research 2021, 10: 3793-3806. PMID: 34733629, PMCID: PMC8512470, DOI: 10.21037/tlcr-21-632.Peer-Reviewed Original ResearchDisease control rateProgression-free survivalObjective response rateSmall cell lung cancerOverall survivalThoracic radiotherapySubgroup analysisRT subgroupPlacebo-controlled phase 2 trialSmall cell lung cancer patientsCell lung cancer patientsPrevious thoracic radiotherapyPrior thoracic radiotherapyRelapsed SCLC patientsPhase 2 trialCell lung cancerLung cancer patientsOS benefitPFS benefitSCLC patientsPlacebo groupPlacebo armRT patientsCancer patientsControl rate
2020
Mutational Profile Evaluates Response and Survival to First‐Line Chemotherapy in Lung Cancer
He Y, Song L, Wang H, Chen P, Liu Y, Sun H, Li X, Dang S, Liu G, Liu X, Chen S, Zhang X, Hofman P, Uchino J, Park HS, Pacheco JM, Tabbò F, Xu M, Dai J, He K, Yang Y, Zhou C, Group W. Mutational Profile Evaluates Response and Survival to First‐Line Chemotherapy in Lung Cancer. Advanced Science 2020, 8: 2003263. PMID: 33643802, PMCID: PMC7887584, DOI: 10.1002/advs.202003263.Peer-Reviewed Original ResearchFirst-line chemotherapyLung cancer patientsLong-term survivalNSCLC patientsCancer patientsLung cancerTherapeutic responseProgression-free survivalMolecular signaturesWhole-exome sequencingLine chemotherapySCLC patientsFree survivalWorse survivalHigh TMBTherapeutic decisionsResults HistologyMolecular subtypesPatientsChemotherapyDifferent subtypesSubtypesLimited biomarkersTissue samplesSurvival
2017
Stage I Lung SBRT Clinical Practice Patterns
Corso CD, Park HS, Moreno AC, Kim AW, Yu JB, Husain ZA, Decker RH. Stage I Lung SBRT Clinical Practice Patterns. American Journal Of Clinical Oncology 2017, 40: 358-361. PMID: 25503436, DOI: 10.1097/coc.0000000000000162.Peer-Reviewed Original ResearchConceptsStereotactic body radiation therapyNational Cancer DatabaseStage I non-small cell lung cancer patientsUse of SBRTNon-small cell lung cancer patientsCell lung cancer patientsStage I NSCLCMajority of patientsClinical practice patternsLung cancer patientsBody radiation therapyMedian BED10SBRT useDosing guidelinesRetrospective studyCancer patientsPrescription trendsCancer DatabasePractice patternsRadiation therapyPatientsDose prescriptionGyRegimensCommon prescription
2015
Comparison of survival outcomes among standard radiotherapy regimens in limited-stage small cell lung cancer patients receiving concurrent chemoradiation
Rutter CE, Park HS, Corso CD, Yeboa DN, Mancini BR, Lester-Coll NH, Kim AW, Decker RH. Comparison of survival outcomes among standard radiotherapy regimens in limited-stage small cell lung cancer patients receiving concurrent chemoradiation. Lung Cancer 2015, 90: 243-248. PMID: 26277031, DOI: 10.1016/j.lungcan.2015.08.002.Peer-Reviewed Original ResearchConceptsSmall cell lung cancerDose-fractionation regimensLimited-stage small cell lung cancerConcurrent CRTConcurrent chemoradiationOverall survivalLimited-stage small-cell lung cancer patientsProportional hazardsSmall cell lung cancer patientsMultivariable Cox proportional hazardsCell lung cancer patientsOptimal radiotherapy doseOngoing randomized trialsInferior overall survivalKaplan-Meier analysisCell lung cancerLarger tumor sizeMedian survival timeLung cancer patientsCox proportional hazardsStandard radiotherapy regimensLarge national datasetChemoradiation regimensSimilar OSEquivalent OS
2011
Impact of Hospital Volume of Thoracoscopic Lobectomy on Primary Lung Cancer Outcomes
Park HS, Detterbeck FC, Boffa DJ, Kim AW. Impact of Hospital Volume of Thoracoscopic Lobectomy on Primary Lung Cancer Outcomes. The Annals Of Thoracic Surgery 2011, 93: 372-379. PMID: 21945225, DOI: 10.1016/j.athoracsur.2011.06.054.Peer-Reviewed Original ResearchConceptsPrimary lung cancer patientsLung cancer patientsShorter LOSMultivariable analysisMedian LOSHospital volumeIndependent predictorsPulmonary lobectomyOpen lobectomyCancer patientsVAT volumeUtilization Project Nationwide Inpatient Sample databaseVideo-assisted thoracoscopic surgery lobectomyHospital operative volumeShorter median LOSLung cancer outcomesPrimary lung cancerHigher hospital volumeShort-term outcomesThoracoscopic surgery lobectomyDiseases procedure codesTotal complicationsHospital lengthHospital morbidityVATS patients