2014
The fate of internalized α5 integrin is regulated by matrix-capable fibronectin
Hsia HC, Nair MR, Corbett SA. The fate of internalized α5 integrin is regulated by matrix-capable fibronectin. Journal Of Surgical Research 2014, 191: 268-279. PMID: 25062814, PMCID: PMC4160403, DOI: 10.1016/j.jss.2014.05.084.Peer-Reviewed Original ResearchConceptsFibronectin matrix assemblyΑ5 integrinFibronectin matrixMatrix assemblySpecific lysine residuesMouse embryo fibroblast cellsEmbryo fibroblast cellsExtracellular spaceIntegrin turnoverCytoplasmic tailTissue-remodeling processesAbsence of fibronectinInternalized receptorsLysine residuesReceptor turnoverIntegrinsTissue remodelingUbiquitinationProtein levelsChinese hamsterFibroblast cellsFibronectin dimersWound repairRapid degradationFate
2005
Fibronectin fragmentation promotes α4β1 integrin-mediated contraction of a fibrin–fibronectin provisional matrix
Valenick LV, Hsia HC, Schwarzbauer JE. Fibronectin fragmentation promotes α4β1 integrin-mediated contraction of a fibrin–fibronectin provisional matrix. Experimental Cell Research 2005, 309: 48-55. PMID: 15992798, DOI: 10.1016/j.yexcr.2005.05.024.Peer-Reviewed Original Research
2004
Coregulation of Fibronectin Signaling and Matrix Contraction by Tenascin-C and Syndecan-4
Midwood KS, Valenick LV, Hsia HC, Schwarzbauer JE. Coregulation of Fibronectin Signaling and Matrix Contraction by Tenascin-C and Syndecan-4. Molecular Biology Of The Cell 2004, 15: 5670-5677. PMID: 15483051, PMCID: PMC532045, DOI: 10.1091/mbc.e04-08-0759.Peer-Reviewed Original ResearchConceptsSyndecan-4 functionsSyndecan-4Actin stress fiber formationFocal adhesion kinaseMatrix contractionStress fiber formationExtracellular matrix proteinsEfficient tissue repairEffects of tenascinProvisional matrixTissue repairHeparan sulfate proteoglycanAdhesion kinaseCell spreadingSignaling pathwaysMatrix proteinsFibronectin signalingThree-dimensional fibrinExtracellular matrixFiber formationSulfate proteoglycanCell interactionsFibroblast morphologyTenascinFibroblast response