2014
The fate of internalized α5 integrin is regulated by matrix-capable fibronectin
Hsia HC, Nair MR, Corbett SA. The fate of internalized α5 integrin is regulated by matrix-capable fibronectin. Journal Of Surgical Research 2014, 191: 268-279. PMID: 25062814, PMCID: PMC4160403, DOI: 10.1016/j.jss.2014.05.084.Peer-Reviewed Original ResearchConceptsFibronectin matrix assemblyΑ5 integrinFibronectin matrixMatrix assemblySpecific lysine residuesMouse embryo fibroblast cellsEmbryo fibroblast cellsExtracellular spaceIntegrin turnoverCytoplasmic tailTissue-remodeling processesAbsence of fibronectinInternalized receptorsLysine residuesReceptor turnoverIntegrinsTissue remodelingUbiquitinationProtein levelsChinese hamsterFibroblast cellsFibronectin dimersWound repairRapid degradationFate
2011
The Fiber Diameter of Synthetic Bioresorbable Extracellular Matrix Influences Human Fibroblast Morphology and Fibronectin Matrix Assembly
Hsia HC, Nair MR, Mintz RC, Corbett SA. The Fiber Diameter of Synthetic Bioresorbable Extracellular Matrix Influences Human Fibroblast Morphology and Fibronectin Matrix Assembly. Plastic & Reconstructive Surgery 2011, 127: 2312-2320. PMID: 21617465, PMCID: PMC3103705, DOI: 10.1097/prs.0b013e3182139fa4.Peer-Reviewed Original ResearchConceptsFibronectin matrix assemblyMatrix assemblyActin cytoskeletal morphologyFocal adhesion complexesFocal adhesion sizeActin stress fibersCell proliferationAdhesion complexesAdhesion sizeEnvironmental cuesStress fibersCellular responsesAbility of scaffoldsCytoskeletal morphologyScaffold fiber diameterHuman dermal fibroblastsFibril formationCell functionImmunofluorescent microscopyBiological responsesMicrofiber scaffoldsFibroblast morphologyDermal fibroblastsHigher cell proliferationCells