2011
Bayesian hierarchical modeling for a non‐randomized, longitudinal fall prevention trial with spatially correlated observations
Murphy TE, Allore HG, Leo‐Summers L, Carlin BP. Bayesian hierarchical modeling for a non‐randomized, longitudinal fall prevention trial with spatially correlated observations. Statistics In Medicine 2011, 30: 522-530. PMID: 21294148, PMCID: PMC3477673, DOI: 10.1002/sim.3912.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsAgedAged, 80 and overAlgorithmsBayes TheoremComputer SimulationConnecticutControlled Clinical Trials as TopicEmergency Medical ServicesFemaleHumansLongitudinal StudiesMaleMarkov ChainsModels, StatisticalMonte Carlo MethodPatient Education as TopicPoisson DistributionTreatment OutcomeConceptsNon-randomized designFall prevention trialsPersons 70 yearsCommunity-based health interventionsNon-randomized interventionsRandomization of participantsInjurious fallsPrevention trialsEmergency departmentFall preventionInterventional effectsLongitudinal trialCare areasConnecticut CollaborationHealth interventionsInterventional designHealthcare interventionsMedicaid ServicesOlder adultsIntervention areaSerious injuriesZip codesTrialsInterventionInfluential covariates
2008
Effect of Dissemination of Evidence in Reducing Injuries from Falls
Tinetti ME, Baker DI, King M, Gottschalk M, Murphy TE, Acampora D, Carlin BP, Leo-Summers L, Allore HG. Effect of Dissemination of Evidence in Reducing Injuries from Falls. New England Journal Of Medicine 2008, 359: 252-261. PMID: 18635430, PMCID: PMC3472807, DOI: 10.1056/nejmoa0801748.Peer-Reviewed Original ResearchConceptsFall-related injuriesSerious fall-related injuriesAdjusted ratesIntervention regionClinical practiceElderly personsPercentage of cliniciansPrimary care cliniciansPrevention of fallsMedical servicesRate of injuryYears of ageEvaluation periodDissemination of evidenceCare cliniciansIntervention visitsOutpatient rehabilitationPreintervention periodFall preventionMorbid conditionsNonrandomized designInjuryReducing InjuryCliniciansRegions of Connecticut
2005
Experimental designs for multicomponent interventions among persons with multifactorial geriatric syndromes
Allore HG, Tinettia M, Gill TM, Peduzzi PN. Experimental designs for multicomponent interventions among persons with multifactorial geriatric syndromes. Clinical Trials 2005, 2: 13-21. PMID: 16279575, DOI: 10.1191/1740774505cn067oa.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsAgedClinical Trials as TopicComorbidityGeriatricsHumansResearch DesignRisk AssessmentRisk FactorsSample SizeSyndromeConceptsMultifactorial health conditionsModifiable risk factorsMulticomponent interventionRisk factorsGeriatric syndromesHealth conditionsMultifactorial geriatric syndromeOutcomes of interestIntervention trialsClinical trialsClinical concernIntervention componentsInterventionSyndromeDeleterious effectsTrialsOutcomesBlindingFactors
2002
A Program to Prevent Functional Decline in Physically Frail, Elderly Persons Who Live at Home
Gill TM, Baker DI, Gottschalk M, Peduzzi PN, Allore H, Byers A. A Program to Prevent Functional Decline in Physically Frail, Elderly Persons Who Live at Home. New England Journal Of Medicine 2002, 347: 1068-1074. PMID: 12362007, DOI: 10.1056/nejmoa020423.Peer-Reviewed Original ResearchConceptsFunctional declineControl groupElderly personsDisability scoresIntervention groupLower-body dressingMore severe disabilityPrevent Functional DeclineHome-based intervention programFrequency of admissionHome-based programSuch functional declinePersons 75 yearsBase lineSevere frailtyPrimary outcomeSubstantial morbidityModerate frailtyMuscle strengthDisability ScalePhysical abilityPhysical therapyDaily livingNursing homesSix months