2023
Associations Between Frailty and the Increased Risk of Adverse Outcomes Among 38,950 UK Biobank Participants With Prediabetes: Prospective Cohort Study
Cao X, Li X, Zhang J, Sun X, Yang G, Zhao Y, Li S, Hoogendijk E, Wang X, Zhu Y, Allore H, Gill T, Liu Z. Associations Between Frailty and the Increased Risk of Adverse Outcomes Among 38,950 UK Biobank Participants With Prediabetes: Prospective Cohort Study. JMIR Public Health And Surveillance 2023, 9: e45502. PMID: 37200070, PMCID: PMC10236284, DOI: 10.2196/45502.Peer-Reviewed Original ResearchConceptsMultiple adverse outcomesChronic kidney diseaseDiabetes-related microvascular diseaseAdverse outcomesCause mortalityCardiovascular diseaseMiddle-aged adultsUK Biobank participantsHigh riskMicrovascular diseaseEye diseaseIncident type 2 diabetes mellitusType 2 diabetes mellitusProportional hazards regression modelsBiobank participantsMultivariable-adjusted modelsProspective cohort studyHazards regression modelsNormal glucose metabolismDiabetes-related burdenDiabetes-related diseasesHealth care resourcesNonfrail counterpartsFrailty assessmentCohort study
2022
Emergency Department Care Transitions for Patients With Cognitive Impairment: A Scoping Review
Gettel CJ, Falvey JR, Gifford A, Hoang L, Christensen LA, Hwang U, Shah MN, Network T, Aggarawal N, Allore H, Amy A, Belleville M, Bellolio M, Betz M, Biese K, Brandt C, Bruursema S, Carnahan R, Carpenter C, Carr D, Chin-Hansen J, Daven M, Degesys N, Dresden M, Dussetschleger J, Ellenbogen M, Falvey J, Foster B, Gettel C, Gifford A, Gilmore-Bykovskyi A, Goldberg E, Han J, Hardy J, Hastings S, Hirshon J, Hoang L, Hogan T, Hung W, Hwang U, Isaacs E, Jaspal N, Jobe D, Johnson J, Kelly K, Kennedy M, Kind A, Leggett J, Malone M, Moccia M, Moreno M, Morrow-Howell N, Nowroozpoor A, Ohuabunwa U, Oiyemhonian B, Perry W, Prusaczk B, Resendez J, Rising K, Sano M, Savage B, Shah M, Suyama J, Swartzberg J, Taylor Z, Vaishal T, Vann A, Webb T, Weintraub S. Emergency Department Care Transitions for Patients With Cognitive Impairment: A Scoping Review. Journal Of The American Medical Directors Association 2022, 23: 1313.e1-1313.e13. PMID: 35247358, PMCID: PMC9378565, DOI: 10.1016/j.jamda.2022.01.076.Peer-Reviewed Original ResearchMeSH KeywordsAgedCognitive DysfunctionEmergency Service, HospitalGeriatric AssessmentHouse CallsHumansPatient TransferConceptsCare transition interventionsRelevant patient-centered outcomesPatient-centered outcomesCognitive impairmentCare partnersTransition interventionsCare transitionsOlder adultsEmergency Department Care TransitionsED revisit ratesSystematic electronic searchFull-text reviewScoping ReviewMedical research databasesGeriatric assessmentSecondary outcomesSystematic scoping reviewED careED patientsED settingPhysical functionFuture investigationsCare coordinationOutpatient careEligible studies
2017
Report: NIA Workshop on Measures of Physiologic Resiliencies in Human Aging
Hadley E, Kuchel G, Newman A, Allore H, Bartley J, Bergeman C, Blinov M, Colon-Emeric C, Dabhar F, Dugan L, Dutta C, Eldadah B, Ferrucci L, Kirkland J, Kritchevsky S, Lipsitz L, Nadkarni N, Reed M, Schmader K, Sierra F, Studenski S, Varadhan R, Walston J, Whitson H, Yung R. Report: NIA Workshop on Measures of Physiologic Resiliencies in Human Aging. The Journals Of Gerontology Series A 2017, 72: 980-990. PMID: 28475732, PMCID: PMC5861884, DOI: 10.1093/gerona/glx015.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFocus of careAging-related factorsLaboratory animal modelsLong-term predictorsMultiple determinantsHuman agingHealthy life spanClinical dataEpidemiological studiesAnimal modelsHuman resiliencyOlder adultsHomeostatic responseAdverse effectsNational InstituteAssessing resilienceResilience outcomesPhenotype definitionResilience data
2013
Modifiable Risk Factors for Pneumonia Requiring Hospitalization of Community‐Dwelling Older Adults: The Health, Aging, and Body Composition Study
Juthani‐Mehta M, De Rekeneire N, Allore H, Chen S, O'Leary JR, Bauer DC, Harris TB, Newman AB, Yende S, Weyant RJ, Kritchevsky S, Quagliarello V, Study F. Modifiable Risk Factors for Pneumonia Requiring Hospitalization of Community‐Dwelling Older Adults: The Health, Aging, and Body Composition Study. Journal Of The American Geriatrics Society 2013, 61: 1111-1118. PMID: 23772872, PMCID: PMC3714374, DOI: 10.1111/jgs.12325.Peer-Reviewed Original ResearchConceptsModifiable risk factorsIncident mobility limitationCommunity-dwelling older adultsBody Composition StudyRisk factorsPlaque scoresMobility limitationsOlder adultsNovel modifiable risk factorsProspective observational cohort studyObservational cohort studyNonmodifiable risk factorsCases of pneumoniaHistory of pneumoniaCommunity-dwelling adultsAverage attributable fractionMonths of baselineCohort studyExpiratory volumePneumonia preventionDental examinationPrimary outcomeOral hygieneMale sexAttributable fractionDynamics of functional aging based on latent-class trajectories of activities of daily living
Han L, Allore H, Murphy T, Gill T, Peduzzi P, Lin H. Dynamics of functional aging based on latent-class trajectories of activities of daily living. Annals Of Epidemiology 2013, 23: 87-92. PMID: 23305692, PMCID: PMC3558979, DOI: 10.1016/j.annepidem.2012.11.010.Peer-Reviewed Original ResearchConceptsDaily livingFunctional agingCommunity-living adultsEquation Poisson modelsMost older adultsADL disabilityHigher disabilityPersistent disabilitySubstantial morbidityInstrumental ADLADL independenceDisability trajectoriesLatent class trajectoriesCumulative burdenRestricted activityLow burdenSevere disabilityMorbidityPredominant trajectoriesOlder adultsDisabilityTime trendsFunctional autonomyADLGrowth mixture models
2005
A case study found that a regression tree outperformed multiple linear regression in predicting the relationship between impairments and Social and Productive Activities scores
Allore H, Tinetti ME, Araujo KL, Hardy S, Peduzzi P. A case study found that a regression tree outperformed multiple linear regression in predicting the relationship between impairments and Social and Productive Activities scores. Journal Of Clinical Epidemiology 2005, 58: 154-161. PMID: 15680749, DOI: 10.1016/j.jclinepi.2004.09.001.Peer-Reviewed Original ResearchMeSH KeywordsAgedData Interpretation, StatisticalGeriatric AssessmentHealth Status IndicatorsHumansLinear ModelsProspective StudiesRegression AnalysisSafety