2013
Dynamics of functional aging based on latent-class trajectories of activities of daily living
Han L, Allore H, Murphy T, Gill T, Peduzzi P, Lin H. Dynamics of functional aging based on latent-class trajectories of activities of daily living. Annals Of Epidemiology 2013, 23: 87-92. PMID: 23305692, PMCID: PMC3558979, DOI: 10.1016/j.annepidem.2012.11.010.Peer-Reviewed Original ResearchConceptsDaily livingFunctional agingCommunity-living adultsEquation Poisson modelsMost older adultsADL disabilityHigher disabilityPersistent disabilitySubstantial morbidityInstrumental ADLADL independenceDisability trajectoriesLatent class trajectoriesCumulative burdenRestricted activityLow burdenSevere disabilityMorbidityPredominant trajectoriesOlder adultsDisabilityTime trendsFunctional autonomyADLGrowth mixture models
2011
Bayesian hierarchical modeling for a non‐randomized, longitudinal fall prevention trial with spatially correlated observations
Murphy TE, Allore HG, Leo‐Summers L, Carlin BP. Bayesian hierarchical modeling for a non‐randomized, longitudinal fall prevention trial with spatially correlated observations. Statistics In Medicine 2011, 30: 522-530. PMID: 21294148, PMCID: PMC3477673, DOI: 10.1002/sim.3912.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsAgedAged, 80 and overAlgorithmsBayes TheoremComputer SimulationConnecticutControlled Clinical Trials as TopicEmergency Medical ServicesFemaleHumansLongitudinal StudiesMaleMarkov ChainsModels, StatisticalMonte Carlo MethodPatient Education as TopicPoisson DistributionTreatment OutcomeConceptsNon-randomized designFall prevention trialsPersons 70 yearsCommunity-based health interventionsNon-randomized interventionsRandomization of participantsInjurious fallsPrevention trialsEmergency departmentFall preventionInterventional effectsLongitudinal trialCare areasConnecticut CollaborationHealth interventionsInterventional designHealthcare interventionsMedicaid ServicesOlder adultsIntervention areaSerious injuriesZip codesTrialsInterventionInfluential covariates
2010
Trajectories of Disability in the Last Year of Life
Gill TM, Gahbauer EA, Han L, Allore HG. Trajectories of Disability in the Last Year of Life. New England Journal Of Medicine 2010, 362: 1173-1180. PMID: 20357280, PMCID: PMC2877372, DOI: 10.1056/nejmoa0909087.Peer-Reviewed Original ResearchConceptsCourse of disabilityDisability trajectoriesOrgan failureAdvanced dementiaSudden deathOlder personsSevere disabilityCommunity-dwelling older personsTrajectories of disabilityLevel of disabilityCatastrophic disabilityEnd of lifeProgressive disabilityFunctional statusDeath certificatesCommon conditionBaseline assessmentPredominant trajectoriesMonthly interviewsDeathDisabilityLongitudinal studyDementiaFrailtyDecedents