2024
Longitudinal Care Network Changes and Associated Healthcare Utilization Among Care Recipients
Liu R, Vander Wyk B, Quiñones A, Allore H. Longitudinal Care Network Changes and Associated Healthcare Utilization Among Care Recipients. Research On Aging 2024, 46: 327-338. PMID: 38261524, PMCID: PMC11472584, DOI: 10.1177/01640275241229162.Peer-Reviewed Original ResearchSkilled-nursing facilityCare recipientsNational Health and Aging Trends StudyGeneralized estimating equation modelsCenters for MedicareLikelihood of hospitalizationMedicaid Services dataCaregiver networkUnpaid caregiversHealthcare utilizationTrends StudyAssociated healthcare utilizationOlder adultsCaregiversRisk ratioSurvey wavesService dataCareHospitalAssociationAdmissionMedicareMedicaidAdultsEquation modeling
2023
THE EFFECT OF CHRONIC CONDITIONS ON DEPRESSIVE SYMPTOMS IS MODERATED BY SEXUAL MINORITY STATUS
Trubits E, Newsom J, Saucedo J, Botoseneanu A, Allore H, Nagel C, Dorr D, Quiñones A. THE EFFECT OF CHRONIC CONDITIONS ON DEPRESSIVE SYMPTOMS IS MODERATED BY SEXUAL MINORITY STATUS. Innovation In Aging 2023, 7: 797-798. PMCID: PMC10737157, DOI: 10.1093/geroni/igad104.2574.Peer-Reviewed Original ResearchSelf-rated healthGreater depressive symptomsChronic conditionsDepressive symptomsOlder adultsEffect of SRHGood self-rated healthRace/ethnicityMinority older adultsYears of educationSymptomsHealth disparitiesMental healthPhysical healthSM adultsAdultsRetirement StudyHealthSexual minority statusDirect effectParticipant sexSame effectGreater numberDisparitiesRACIAL/ETHNIC AND MULTIMORBIDITY DIFFERENCES IN DEMENTIA ONSET AMONG MIDDLE-AGED AND OLDER ADULTS
Chen S, Nagel C, Botoseneanu A, Allore H, Newsom J, Thielke S, Kaye J, Quiñones A. RACIAL/ETHNIC AND MULTIMORBIDITY DIFFERENCES IN DEMENTIA ONSET AMONG MIDDLE-AGED AND OLDER ADULTS. Innovation In Aging 2023, 7: 747-747. PMCID: PMC10737488, DOI: 10.1093/geroni/igad104.2416.Peer-Reviewed Original ResearchDementia onsetRace/ethnicityHigh riskOlder adultsModifiable risk factorsNon-Hispanic blacksCovariate-adjusted modelsContext of multimorbidityNon-Hispanic white respondentsNon-Hispanic White older adultsWhite older adultsRacial/EthnicMultimorbidity combinationsRisk factorsDiscrete-time survival modelsHigh prevalenceHigher oddsMultimorbidityWhite adultsDementiaMiddle AgedLater lifeAdultsSignificant differencesRiskLATENT CLASSES OF MULTIMORBIDITY AND ASSOCIATED CARE-RECEIVING CHARACTERISTICS FOR US OLDER ADULTS
Liu M, Nagel C, Chen S, Kaye J, Allore H, Quiñones A. LATENT CLASSES OF MULTIMORBIDITY AND ASSOCIATED CARE-RECEIVING CHARACTERISTICS FOR US OLDER ADULTS. Innovation In Aging 2023, 7: 823-823. PMCID: PMC10739216, DOI: 10.1093/geroni/igad104.2654.Peer-Reviewed Original ResearchOlder adultsCare needsMore unmet needsDifferent care needsType of careAging Trends StudyMultimorbidity combinationsMultimorbidity patternsMusculoskeletal conditionsChronic conditionsNational HealthMedian numberUnmet needAssociated careMultimorbidityCareIADL domainsLatent classesAbstract Older adultsAdultsFurther investigationFour-class solutionHealthy classCaregiversSmall proportionAntibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study
Datta R, Han L, Doyle M, Allore H, Sanft T, Quagliarello V, Juthani-Mehta M. Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study. Palliative Medicine 2023, 37: 793-798. PMID: 36999898, DOI: 10.1177/02692163231162889.Peer-Reviewed Original ResearchConceptsAdverse drug eventsAntibiotic therapyDrug eventsAdvanced cancerOlder adultsIndex admissionPalliative chemotherapyCohort studyTertiary care centerHospitalized older adultsPalliative care providersMultidrug-resistant organismsMean ageCommon tumorsCare centerCare providersRatio of daysSolid tumorsMultivariable testingPatientsTherapyStandardized criteriaCancerMean timeAdultsRacial, ethnic, and socioeconomic disparities in trajectories of morbidity accumulation among older Americans
O'Neill A, Newsom J, Trubits E, Elman M, Botoseneanu A, Allore H, Nagel C, Dorr D, Quiñones A. Racial, ethnic, and socioeconomic disparities in trajectories of morbidity accumulation among older Americans. SSM - Population Health 2023, 22: 101375. PMID: 36941895, PMCID: PMC10024041, DOI: 10.1016/j.ssmph.2023.101375.Peer-Reviewed Original ResearchHispanic adultsRace/ethnicityBlack adultsWhite adultsMultiple chronic health conditionsNon-Hispanic white adultsNH White adultsChronic health conditionsSelf-reported morbidityCovariate-adjusted modelsPublic health interventionsProtective effectMorbidity countHealth interventionsPotential associationHealth disparitiesOlder ageSocioeconomic disparitiesHealth conditionsSocioeconomic statusSocioeconomic inequalitiesAdultsOlder AmericansRetirement StudyConsiderable heterogeneityPlatelet response to influenza vaccination reflects effects of aging
Konstorum A, Mohanty S, Zhao Y, Melillo A, Vander Wyk B, Nelson A, Tsang S, Blevins T, Belshe R, Chawla D, Rondina M, Gill T, Montgomery R, Allore H, Kleinstein S, Shaw A. Platelet response to influenza vaccination reflects effects of aging. Aging Cell 2023, 22: e13749. PMID: 36656789, PMCID: PMC9924941, DOI: 10.1111/acel.13749.Peer-Reviewed Original ResearchConceptsCommunity-dwelling older adultsPlatelet activationOlder adultsInfluenza vaccinationAge-associated chronic inflammationInfluence platelet functionRNA expressionPro-inflammatory diseasesAge-associated increasePlatelet activation pathwaysAge-associated differencesActivation pathwayPlatelet transcriptomeGeriatric conditionsChronic inflammationImmune responsePlatelet functionPlatelet responseSNF residentsVaccinationActivation responseYoung individualsProtein levelsAdultsYounger participants
2022
MULTIMORBIDITY PROGRESSION AMONG MEDICARE BENEFICIARIES IN THE HEALTH AND RETIREMENT STUDY (1991–2015)
Quiñones A, Markwardt S, Bobo M, Allore H, Newsom J, Nagel C, Botoseneanu A, Dorr D. MULTIMORBIDITY PROGRESSION AMONG MEDICARE BENEFICIARIES IN THE HEALTH AND RETIREMENT STUDY (1991–2015). Innovation In Aging 2022, 6: 693-693. DOI: 10.1093/geroni/igac059.2540.Peer-Reviewed Original ResearchMultimorbidity groupObese body mass indexOlder adultsLevel of multimorbidityBody mass indexHigh incidence rateHigh multimorbidityMass indexIncidence rateED ratesMultimorbidityMedicare beneficiariesMedicare feeBirth cohortService beneficiariesLower multimorbidityFunctional lossGreater riskSociodemographic differencesDisease accumulationLater lifeAbstract Older adultsRetirement StudyHigher proportionAdults
2021
Racial and Ethnic Differences in Multimorbidity Changes Over Time
Quiñones AR, Newsom JT, Elman MR, Markwardt S, Nagel CL, Dorr DA, Allore HG, Botoseneanu A. Racial and Ethnic Differences in Multimorbidity Changes Over Time. Medical Care 2021, 59: 402-409. PMID: 33821829, PMCID: PMC8024615, DOI: 10.1097/mlr.0000000000001527.Peer-Reviewed Original ResearchConceptsMinimal diseaseOlder adultsProspective cohort studyHigher depressive symptomsMultimorbidity combinationsEthnic older adultsCohort studyMultimorbidity patternsLung diseaseHeart diseaseRetirement Study respondentsDelay progressionDepressive symptomsMultimorbidityDiseaseLatent class analysisLatent classesEthnic differencesWhite AmericansStudy respondentsMultinomial logistic modelAdultsClass analysisLogistic modelParticipants
2020
Reform influences location of death: Interrupted time-series analysis on older adults and persons with dementia
Vroomen J, Kjellstadli C, Allore HG, van der Steen JT, Husebo B. Reform influences location of death: Interrupted time-series analysis on older adults and persons with dementia. PLOS ONE 2020, 15: e0241132. PMID: 33147248, PMCID: PMC7641450, DOI: 10.1371/journal.pone.0241132.Peer-Reviewed Original ResearchConceptsLocation of deathInterrupted time series analysisHome deathOlder adultsCoordination ReformNursing homesNursing home deathsAdults 65 yearsOlder adults 65 yearsHospital deathDeath RegistryNorwegian CausePrimary outcomeAdult decedentsDeath certificatesHospitalDementiaMortality dataCare infrastructureHome careDeathPopulation-level studiesAdultsPublic healthNumber of people
2014
A dynamic trajectory class model for intensive longitudinal categorical outcome
Lin H, Han L, Peduzzi PN, Murphy TE, Gill TM, Allore HG. A dynamic trajectory class model for intensive longitudinal categorical outcome. Statistics In Medicine 2014, 33: 2645-2664. PMID: 24519416, PMCID: PMC4145078, DOI: 10.1002/sim.6109.Peer-Reviewed Original Research
2009
Missing Data: A Special Challenge in Aging Research
Hardy SE, Allore H, Studenski SA. Missing Data: A Special Challenge in Aging Research. Journal Of The American Geriatrics Society 2009, 57: 722-729. PMID: 19220562, PMCID: PMC2695652, DOI: 10.1111/j.1532-5415.2008.02168.x.Peer-Reviewed Original Research