2022
External validation of a model determining risk of neoplastic progression of Barrett’s esophagus in a cohort of U.S. veterans
Nguyen T, Thrift A, Ketwaroo G, Du X, Leon Novelo L, George R, Rosen D, El-Serag H. External validation of a model determining risk of neoplastic progression of Barrett’s esophagus in a cohort of U.S. veterans. Gastrointestinal Endoscopy 2022, 95: 1113-1122. PMID: 34998796, PMCID: PMC9119926, DOI: 10.1016/j.gie.2021.12.034.Peer-Reviewed Original ResearchConceptsHigh-grade dysplasiaHigh-risk groupEsophageal adenocarcinomaBarrett's esophagusBE patientsDiscriminatory abilityHouston Veterans Affairs Medical CenterVeterans Affairs Medical CenterHGD/esophageal adenocarcinomaRetrospective cohort studyExternal validationExternal validation studyInitial EGDCohort studyConsecutive patientsSmoking statusDysplasia statusRisk groupsMedical CenterHigh riskGeneral populationNew diagnosisPatientsClinical practiceBiopsy sampling
2019
Scope of Burnout Among Young Gastroenterologists and Practical Solutions from Gastroenterology and Other Disciplines
Barnes E, Ketwaroo G, Shields H. Scope of Burnout Among Young Gastroenterologists and Practical Solutions from Gastroenterology and Other Disciplines. Digestive Diseases And Sciences 2019, 64: 302-306. PMID: 30607687, DOI: 10.1007/s10620-018-5443-3.Peer-Reviewed Original Research
2017
The Impact of Risk Factors of Chronic Pancreatitis on Secretin Pancreatic Function Testing
Kothari D, Ketwaroo G, Freedman S, Sheth S. The Impact of Risk Factors of Chronic Pancreatitis on Secretin Pancreatic Function Testing. Pancreas 2017, 46: 887-890. PMID: 28697128, DOI: 10.1097/mpa.0000000000000871.Peer-Reviewed Original ResearchConceptsRecurrent acute pancreatitisPeak bicarbonate concentrationHistory of APAcute pancreatitisRisk factorsPancreatic function testingChronic pancreatitisLocal complicationsFunction testingFemale sexBicarbonate concentrationRetrospective reviewUnivariate analysisFamily historyTobacco usePancreatitisPatientsMultivariate analysisAlcohol useComplicationsSignificant differencesSexFactorsHistory
2016
Risk Profiles for Barrett’s Esophagus Differ between New and Prevalent, and Long- and Short-Segment Cases
Tan M, Murrey-Ittmann J, Nguyen T, Ketwaroo G, El-Serag H, Thrift A. Risk Profiles for Barrett’s Esophagus Differ between New and Prevalent, and Long- and Short-Segment Cases. PLOS ONE 2016, 11: e0169250. PMID: 28036381, PMCID: PMC5201279, DOI: 10.1371/journal.pone.0169250.Peer-Reviewed Original ResearchConceptsSpecialized intestinal metaplasiaShort-segment BELong-segment BEPrimary care controlsH. pylori infectionRisk factorsGERD symptomsElective esophagogastroduodenoscopyEndoscopy controlsCare controlPylori infectionCase definitionBE casesControl groupGastroesophageal reflux disease symptomsMultivariate logistic regression modelFrequent GERD symptomsPrimary care clinicsCross-sectional studyVeterans Affairs centersLogistic regression modelsEligible patientsH2RA useMedication useCare clinics
2015
High Glasgow Blatchford Score at admission is associated with recurrent bleeding after discharge for patients hospitalized with upper gastrointestinal bleeding
Sengupta N, Tapper E, Patwardhan V, Ketwaroo G, Thaker A, Leffler D, Feuerstein J. High Glasgow Blatchford Score at admission is associated with recurrent bleeding after discharge for patients hospitalized with upper gastrointestinal bleeding. Endoscopy 2015, 48: 9-15. PMID: 26340604, DOI: 10.1055/s-0034-1392651.Peer-Reviewed Original ResearchConceptsGlasgow-Blatchford scoreUpper gastrointestinal bleedingGBS scoresBlatchford scoreGastrointestinal bleedingMultivariable analysisEndoscopic interventionHigh riskIntensive care unit admissionCare unit admissionMultivariable Cox regressionPost-discharge outcomesGBS patientsUnit admissionCause readmissionHospital deathRecurrent bleedingCohort studyReadmission ratesConsecutive patientsHospital readmissionSignificant morbidityCox regressionPatientsReadmissionRisk Factors for Adverse Outcomes in Patients Hospitalized With Lower Gastrointestinal Bleeding
Sengupta N, Tapper E, Patwardhan V, Ketwaroo G, Thaker A, Leffler D, Feuerstein J. Risk Factors for Adverse Outcomes in Patients Hospitalized With Lower Gastrointestinal Bleeding. Mayo Clinic Proceedings 2015, 90: 1021-1029. PMID: 26141075, PMCID: PMC4770256, DOI: 10.1016/j.mayocp.2015.04.024.Peer-Reviewed Original ResearchConceptsRecurrent lower gastrointestinal bleedingLower gastrointestinal bleedingCharlson Comorbidity Index scoreComorbidity Index scoreActive malignancyRisk factorsGastrointestinal bleedingAdverse outcomesMultivariable Cox proportional hazards regression modelsHigher Charlson Comorbidity Index scoresIndex scoreCox proportional hazards regression modelProportional hazards regression modelsBeth Israel Deaconess Medical CenterProspective observational studyHazards regression modelsAssociation of variablesRecurrent bleedingHospital dischargeConsecutive patientsHospital readmissionObservational studyMedical CenterMortality riskPatientsApproach to Patients With Suspected Chronic Pancreatitis
Ketwaroo G, Freedman S, Sheth S. Approach to Patients With Suspected Chronic Pancreatitis. Pancreas 2015, 44: 173-180. PMID: 25675419, DOI: 10.1097/mpa.0000000000000239.Peer-Reviewed Original ResearchConceptsChronic pancreatitisEarly diagnosisSignificant health care burdenSignificant health care resourcesNonspecific abdominal painEarly chronic pancreatitisHealth care burdenHealth care resourcesCurrent diagnostic testsAbdominal painPancreatic changesCare burdenLarge cohortCare resourcesPatientsDiagnostic testsDiagnosisPancreatitisAvailable literaturePainCohort