Featured Publications
Estimating deaths averted and cost per life saved by scaling up mRNA COVID-19 vaccination in low-income and lower-middle-income countries in the COVID-19 Omicron variant era: a modelling study
Savinkina A, Bilinski A, Fitzpatrick M, Paltiel AD, Rizvi Z, Salomon J, Thornhill T, Gonsalves G. Estimating deaths averted and cost per life saved by scaling up mRNA COVID-19 vaccination in low-income and lower-middle-income countries in the COVID-19 Omicron variant era: a modelling study. BMJ Open 2022, 12: e061752. PMID: 36100306, PMCID: PMC9471205, DOI: 10.1136/bmjopen-2022-061752.Peer-Reviewed Original ResearchConceptsLow-income countriesIncome countriesDeath avertedHigh-income nationsStatistical lifeAvertable deathsIncome nationsCOVID-19 deathsReasonable investmentHigh costKey inputCountriesParameter estimatesAvertedCostSensitivity analysisUniversal vaccinationGlobal vaccinationMRNA COVID-19 vaccinationNationsInvestmentPrimary vaccine seriesLow vaccine effectivenessCOVID-19 vaccinationPublic data
2024
Comparing frequency of booster vaccination to prevent severe COVID-19 by risk group in the United States
Park H, Gonsalves G, Tan S, Kelly J, Rutherford G, Wachter R, Schechter R, Paltiel A, Lo N. Comparing frequency of booster vaccination to prevent severe COVID-19 by risk group in the United States. Nature Communications 2024, 15: 1883. PMID: 38448400, PMCID: PMC10917753, DOI: 10.1038/s41467-024-45549-9.Peer-Reviewed Original ResearchConceptsSevere COVID-19Risk of severe COVID-19COVID-19 booster vaccinationBooster vaccinationHigh-risk populationAbsolute annual riskWaning of protectionImmunocompromised populationsFrequent boostingOlder age groupsAnnual boosterImmune evasionImmunocompromised personsPublic health needsPublic health guidanceRisk groupsFrequent boostersImmune statusRisk factorsFrequency of booster vaccinationHealth needsHealth guidanceCompare frequenciesAge groupsVaccine
2023
Using Bandit Algorithms to Maximize SARS-CoV-2 Case-Finding: Evaluation and Feasibility Study
Rayo M, Faulkner D, Kline D, Thornhill T, Malloy S, Della Vella D, Morey D, Zhang N, Gonsalves G. Using Bandit Algorithms to Maximize SARS-CoV-2 Case-Finding: Evaluation and Feasibility Study. JMIR Public Health And Surveillance 2023, 9: e39754. PMID: 37581924, PMCID: PMC10430782, DOI: 10.2196/39754.Peer-Reviewed Original ResearchConceptsSARS-CoV-2COVID-19 annual update: a narrative review
Biancolella M, Colona V, Luzzatto L, Watt J, Mattiuz G, Conticello S, Kaminski N, Mehrian-Shai R, Ko A, Gonsalves G, Vasiliou V, Novelli G, Reichardt J. COVID-19 annual update: a narrative review. Human Genomics 2023, 17: 68. PMID: 37488607, PMCID: PMC10367267, DOI: 10.1186/s40246-023-00515-2.Peer-Reviewed Original ResearchPlanning for Mpox on a College Campus: A Model-Based Decision-Support Tool.
Savinkina A, Chitwood M, Kwon J, Pitzer V, Gonsalves G, Paltiel A. Planning for Mpox on a College Campus: A Model-Based Decision-Support Tool. Annals Of Internal Medicine 2023, 176: 340-347. PMID: 36716454, PMCID: PMC10338074, DOI: 10.7326/m22-2734.Peer-Reviewed Original ResearchConceptsSustained transmissionNational InstituteLow-risk groupHigh-risk populationPopulation of MSMHealth-National InstituteResidential college campusSymptomatic casesHypothetical cohortCongregate settingsStudy populationPreemptive vaccinationReactive vaccinationInfectious diseasesVaccinationDrug abuseBasic reproductive numberFuture outbreaksFrequent physical contactMSMReproductive numberOutbreakDaysMenTimely detection
2022
Monkeypox, COVID-19, AIDS: have we progressed so little?
Gonsalves G. Monkeypox, COVID-19, AIDS: have we progressed so little? Nature 2022, 609: 443-443. PMID: 36100678, DOI: 10.1038/d41586-022-02917-z.Peer-Reviewed Original ResearchConceptsFailure of technologyMonkeypox Emergency: Urgent Questions and Perspectives
Rothenburg S, Yang Z, Beard P, Sawyer S, Titanji B, Gonsalves G, Kindrachuk J. Monkeypox Emergency: Urgent Questions and Perspectives. Cell 2022, 185: 3279-3281. PMID: 35998628, PMCID: PMC9395144, DOI: 10.1016/j.cell.2022.08.002.Peer-Reviewed Original ResearchEnd COVID-19 in low- and middle-income countries
Mobarak AM, Miguel E, Abaluck J, Ahuja A, Alsan M, Banerjee A, Breza E, Chandrasekhar AG, Duflo E, Dzansi J, Garrett D, Goldsmith-Pinkham P, Gonsalves GS, Hossain MM, Jakubowski A, Kang G, Kharel A, Kremer M, Meriggi N, Nekesa C, Olken BA, Omer SB, Qadri F, Rees H, Salako B, Voors M, Warren S, Więcek W. End COVID-19 in low- and middle-income countries. Science 2022, 375: 1105-1110. PMID: 35271319, DOI: 10.1126/science.abo4089.Commentaries, Editorials and Letters
2021
Unequal global vaccine coverage is at the heart of the current covid-19 crisis
Hassan F, London L, Gonsalves G. Unequal global vaccine coverage is at the heart of the current covid-19 crisis. The BMJ 2021, 375: n3074. PMID: 34903557, DOI: 10.1136/bmj.n3074.Peer-Reviewed Original ResearchAdventures in COVID-19 Policy Modeling: Education Edition
Gonsalves GS, Salomon JA, Thornhill T, Paltiel AD. Adventures in COVID-19 Policy Modeling: Education Edition. Current HIV/AIDS Reports 2021, 19: 94-100. PMID: 34826066, PMCID: PMC8617548, DOI: 10.1007/s11904-021-00592-9.Peer-Reviewed Original ResearchUnderstanding the Barriers to Pooled SARS-CoV-2 Testing in the United States
Fenichel EP, Koch RT, Gilbert A, Gonsalves G, Wyllie AL. Understanding the Barriers to Pooled SARS-CoV-2 Testing in the United States. Microbiology Spectrum 2021, 9: 10.1128/spectrum.00312-21. PMID: 34378949, PMCID: PMC8552767, DOI: 10.1128/spectrum.00312-21.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 testingSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detectionPooled testingPooled testing strategyClinical Laboratory Improvement AmendmentsTraditional diagnostic testingEmergence of variantsTesting strategiesDiagnostic testingVirus resurgenceEarly detectionClear protocolsTest capacityTesting capacityUnited StatesTest priceSurveillance measuresTest reportingMajor barrierUptakeAdequate resourcesResponseTestingTesting programU.S. laboratoriesMaximizing the Efficiency of Active Case Finding for SARS-CoV-2 Using Bandit Algorithms
Gonsalves GS, Copple JT, Paltiel AD, Fenichel EP, Bayham J, Abraham M, Kline D, Malloy S, Rayo MF, Zhang N, Faulkner D, Morey DA, Wu F, Thornhill T, Iloglu S, Warren JL. Maximizing the Efficiency of Active Case Finding for SARS-CoV-2 Using Bandit Algorithms. Medical Decision Making 2021, 41: 970-977. PMID: 34120510, PMCID: PMC8484027, DOI: 10.1177/0272989x211021603.Peer-Reviewed Original ResearchConceptsBandit algorithmsMobility dataThompson sampling algorithmWeb appFunctional prototypeTesting resourcesSequential decisionAlgorithmPartial informationSampling algorithmClassic problemDecision scienceSpatial correlationAllocationPoint distanceInformationResourcesDeploymentAppsDecisionsTradeoffHaystackPrototypeObjectsDataAdaptive Policies to Balance Health Benefits and Economic Costs of Physical Distancing Interventions during the COVID-19 Pandemic
Yaesoubi R, Havumaki J, Chitwood MH, Menzies NA, Gonsalves G, Salomon JA, Paltiel AD, Cohen T. Adaptive Policies to Balance Health Benefits and Economic Costs of Physical Distancing Interventions during the COVID-19 Pandemic. Medical Decision Making 2021, 41: 386-392. PMID: 33504258, PMCID: PMC8084913, DOI: 10.1177/0272989x21990371.Peer-Reviewed Original ResearchConceptsAdaptive policiesClear decision rulesSocial costsEconomic costsPolicy makersPhysical distancing policiesDecision toolPolicyPhysical distancing interventionsDistancing policiesModel-based experimentsDecision rulesReal-time surveillance dataCostCOVID-19 pandemicMakersShorter overall durationMore complex modelsHealth benefitsComplex modelsPandemicCurrent pandemicCOVID-19BenefitsRulesEviction, Health Inequity, and the Spread of COVID-19: Housing Policy as a Primary Pandemic Mitigation Strategy
Benfer EA, Vlahov D, Long MY, Walker-Wells E, Pottenger JL, Gonsalves G, Keene D. Eviction, Health Inequity, and the Spread of COVID-19: Housing Policy as a Primary Pandemic Mitigation Strategy. Journal Of Urban Health 2021, 98: 1-12. PMID: 33415697, PMCID: PMC7790520, DOI: 10.1007/s11524-020-00502-1.Peer-Reviewed Original ResearchConceptsNon-Hispanic whitesHealth inequitiesPandemic mitigation strategiesInfection rateCOVID-19COVID-19 infectionCOVID-19 infection ratesRacial health inequitiesNegative health effectsSupportive measuresHealth outcomesLow-income populationsHealth effectsUnprecedented unemployment ratesPandemic control strategiesDecreased abilityCOVID-19 pandemicPublic healthRecent dataCOVID-19 spreadDisproportionate ratesPrevention policiesPreventionDeathRecent studies
2020
Preventing the Spread of COVID-19 in Immigration Detention Centers Requires the Release of Detainees.
Lopez WD, Kline N, LeBrón AMW, Novak NL, De Trinidad Young ME, Gonsalves G, Mishori R, Safi BA, Kysel IM. Preventing the Spread of COVID-19 in Immigration Detention Centers Requires the Release of Detainees. American Journal Of Public Health 2020, 111: 110-115. PMID: 33211577, PMCID: PMC7750591, DOI: 10.2105/ajph.2020.305968.Peer-Reviewed Original ResearchMeSH KeywordsAdultChildCOVID-19Emigration and ImmigrationHumansJailsTransients and MigrantsUnited StatesPolitical interference in public health science during covid-19
Gonsalves G, Yamey G. Political interference in public health science during covid-19. The BMJ 2020, 371: m3878. PMID: 33023874, DOI: 10.1136/bmj.m3878.Peer-Reviewed Original ResearchDonald Trump: a political determinant of covid-19
Yamey G, Gonsalves G. Donald Trump: a political determinant of covid-19. The BMJ 2020, 369: m1643. PMID: 32332028, DOI: 10.1136/bmj.m1643.Peer-Reviewed Original Research