2001
Cerebral blood flow in obsessive–compulsive patients with major depression: effect of treatment with sertraline or desipramine on treatment responders and non-responders
Hoehn-Saric R, Schlaepfer T, Greenberg B, McLeod D, Pearlson G, Wong S. Cerebral blood flow in obsessive–compulsive patients with major depression: effect of treatment with sertraline or desipramine on treatment responders and non-responders. Psychiatry Research 2001, 108: 89-100. PMID: 11738543, DOI: 10.1016/s0925-4927(01)00114-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBlood Flow VelocityCerebral CortexDepressive Disorder, MajorDesipramineDominance, CerebralDouble-Blind MethodFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedObsessive-Compulsive DisorderRegional Blood FlowSertralineTomography, Emission-Computed, Single-PhotonTreatment OutcomeConceptsRegional cerebral blood flowHigher regional cerebral blood flowWeeks of treatmentCerebral blood flowYale-Brown Obsessive Compulsive ScaleBlood flowTemporal regionsType of medicationEffects of sertralineMajor depressive episodePrefrontal regional cerebral blood flowAdministration of medicationsPrefrontal regionsHMPAO SPECT scansEffect of treatmentObsessive Compulsive ScaleDiffuse reductionRCBF reductionStudy entryBasal gangliaDepressive episodeClinical changesMajor depressionDrug treatmentTreatment responders
1993
Single Photon Emission Computed Tomography in Obsessive-Compulsive Disorder
Harris G, Pearlson G, Hoehn-Saric R. Single Photon Emission Computed Tomography in Obsessive-Compulsive Disorder. JAMA Psychiatry 1993, 50: 498-499. PMID: 8498888, DOI: 10.1001/archpsyc.1993.01820180100015.Peer-Reviewed Original ResearchConceptsOrbital frontal regionsObsessive-compulsive disorderSingle photon emissionBlood flowRegional cerebral blood flowCortical blood flowGroup of patientsCerebral blood flowMedial frontal regionsSPECT studiesAnatomical locationPatientsCompulsive disorderPhoton emissionEt al1DisordersTomographyGroup
1991
User-friendly method for rapid brain and CSF volume calculation using transaxial MRI images
Harris G, Rhew E, Noga T, Pearlson G. User-friendly method for rapid brain and CSF volume calculation using transaxial MRI images. Psychiatry Research 1991, 40: 61-68. PMID: 1946841, DOI: 10.1016/0925-4927(91)90029-p.Peer-Reviewed Original Research