2000
Elucidating the contributions of processing speed, executive ability, and frontal lobe volume to normal age-related differences in fluid intelligence
SCHRETLEN D, PEARLSON G, ANTHONY J, AYLWARD E, AUGUSTINE A, DAVIS A, BARTA P. Elucidating the contributions of processing speed, executive ability, and frontal lobe volume to normal age-related differences in fluid intelligence. Journal Of The International Neuropsychological Society 2000, 6: 52-61. PMID: 10761367, DOI: 10.1017/s1355617700611062.Peer-Reviewed Original ResearchConceptsPerceptual comparison speedFluid intelligenceExecutive abilitiesFrontal lobe volumeProcessing speedProcessing speed theorySimple processing speedHierarchical multiple regression analysisComparison speedFrontal brain structuresLobe volumeAge-related differencesAge-related declineNormal age-related differencesCognitive agingRegional brain volumesSpeed theoryMultiple regression analysisBrain structuresIntelligenceAge-related variationsBrain volumeNormal adultsMagnetic resonance imagingSame decline
1998
SPECT brain blood flow changes with continuous ligand infusion during previously-learned WCST performance
Tien A, Schlaepfer T, Orr W, Pearlson G. SPECT brain blood flow changes with continuous ligand infusion during previously-learned WCST performance. Psychiatry Research 1998, 82: 47-52. PMID: 9645550, DOI: 10.1016/s0925-4927(98)00003-1.Peer-Reviewed Original ResearchConceptsWisconsin Card Sorting TestBrain blood flow changesBlood flow changesInferior parietal cortexBrain activation patternsBilateral inferior frontalBlood flowNormal subjectsTemporal cortexAnterior cingulateParietal cortexCard Sorting TestInferior frontalInfusionWCST performanceFlow changesCortexSorting TestHippocampusCaudateCingulate
1997
Measurement of frontal lobe volume on magnetic resonance imaging scans
Aylward E, Augustine A, Li Q, Barta P, Pearlson G. Measurement of frontal lobe volume on magnetic resonance imaging scans. Psychiatry Research 1997, 75: 23-30. PMID: 9287371, DOI: 10.1016/s0925-4927(97)00026-7.Peer-Reviewed Original Research
1995
Posterior superior temporal gyrus in schizophrenia: grey matter changes and clinical correlates
Menon R, Barta P, Aylward E, Richards S, Vaughn D, Tien A, Harris G, Pearlson G. Posterior superior temporal gyrus in schizophrenia: grey matter changes and clinical correlates. Schizophrenia Research 1995, 16: 127-135. PMID: 7577766, DOI: 10.1016/0920-9964(94)00067-i.Peer-Reviewed Original Research
1986
Cold Water Stress Abolishes Hyperactivity Produced by Cortical Suction Lesions Without Altering Noradrenergic Depletion
Moran T, Zern K, Pearlson G, Kubos K, Robinson R. Cold Water Stress Abolishes Hyperactivity Produced by Cortical Suction Lesions Without Altering Noradrenergic Depletion. Behavioral Neuroscience 1986, 100: 422-426. PMID: 3730151, DOI: 10.1037/0735-7044.100.3.422.Peer-Reviewed Original ResearchConceptsSuction lesionsControl animalsSham-operated control animalsFirst postoperative weekWeekly intervalsDevelopment of hyperactivityCold water swimmingPostoperative periodNoradrenergic depletionNorepinephrine depletionPostoperative weekCatecholamine depletionBehavioral hyperactivitySwim testLesion groupLesionsHyperactivityWeekly stress
1984
Effect of anterior-posterior lesion location on the asymmetrical behavioral and biochemical response to cortical suction ablations in the rat
Pearlson G, Kubos K, Robinson R. Effect of anterior-posterior lesion location on the asymmetrical behavioral and biochemical response to cortical suction ablations in the rat. Brain Research 1984, 293: 241-250. PMID: 6697218, DOI: 10.1016/0006-8993(84)91231-9.Peer-Reviewed Original ResearchConceptsSuction ablationLesion locationRight hemisphereConcentrations of norepinephrineContralateral cortexCortical lesionsAnterior lesionsLocus coeruleusSpontaneous activityNeurotransmitter pathwaysLocomotor activityGreater reductionLesionsRatsCortexBehavioral findingsBiochemical responsesAblationAnalysis of varianceAnterior-posterior axisNorepinephrineCoeruleusHyperactivityHemisphere
1982
CT scan and neuropsychological correlates of Alzheimer's Disease and Huntington's Disease
Veroff A, Pearlson G, Ahn H. CT scan and neuropsychological correlates of Alzheimer's Disease and Huntington's Disease. Brain And Cognition 1982, 1: 177-184. PMID: 6242676, DOI: 10.1016/0278-2626(82)90015-x.Peer-Reviewed Original ResearchConceptsDisease patientsAlzheimer's diseaseAlzheimer's disease patientsCT scan interpretationHuntington's disease patientsCT scan informationCT attenuation valuesClinical characteristicsPrimary neuropathologyDementia syndromesCT scanScan interpretationNormal agingDiseaseHuntington's diseaseAphasia subtypesNeuropsychological correlatesPatientsSignificant correlationDouble dissociationAttenuation valuesRecent studiesScan informationLobe densityNeuropathology