1990
Demonstration of naturalistic methods for cocaine smoking by human volunteers
Foltin R, Fischman M, Nestadt G, Stromberger H, Cornell E, Pearlson G. Demonstration of naturalistic methods for cocaine smoking by human volunteers. Drug And Alcohol Dependence 1990, 26: 145-154. PMID: 2242715, DOI: 10.1016/0376-8716(90)90121-t.Peer-Reviewed Original ResearchConceptsVenous blood levelsClinical research unitBlood level curvesFirst doseSubsequent dosesBlood pressureDosing sessionsBlood levelsAcute toleranceCocaine smokingHeart rateDose sessionAscending limbBaseline levelsCardiovascular activityHuman volunteersSubjective effectsTransient increaseResearch volunteersDosesMale research volunteersCocaineVolunteersSubjectsLimb
1987
Marijuana and cocaine interactions in humans: Cardiovascular consequences
Foltin R, Fischman M, Pedroso J, Pearlson G. Marijuana and cocaine interactions in humans: Cardiovascular consequences. Pharmacology Biochemistry And Behavior 1987, 28: 459-464. PMID: 2829241, DOI: 10.1016/0091-3057(87)90506-5.Peer-Reviewed Original ResearchConceptsMean arterial pressureCombination of cocaineHeart rateArterial pressureBaseline cardiovascular indexesAdult male volunteersDose-dependent increaseDoses of cocaineCardiovascular consequencesResearch wardBlood levelsMale volunteersDaily experimental sessionsMarijuana smokingCocaine interactionsIntravenous cocaineCardiovascular indicesMarijuana cigarettesCocaineCocaine hydrochlorideDependent increaseSimilar increaseMarijuanaExperimental sessionsSmoking