2015
Obesity-Related Genetic Variants and their Associations with Physical Activity
Lee H, Ash GI, Angelopoulos TJ, Gordon PM, Moyna NM, Visich PS, Zoeller RF, Gordish-Dressman H, Deshpande V, Chen MH, Thompson PD, Hoffman EP, Devaney JM, Pescatello LS. Obesity-Related Genetic Variants and their Associations with Physical Activity. Sports Medicine - Open 2015, 1: 34. PMID: 26495240, PMCID: PMC4607705, DOI: 10.1186/s40798-015-0036-6.Peer-Reviewed Original ResearchNeuronal growth regulator 1Physical activityObesity-related genetic variantsPaffenbarger Physical Activity QuestionnaireLight-intensity physical activityPhysical activity volumePhysical Activity QuestionnaireIntensity physical activityHours/weekGenetic variantsActivity QuestionnaireFat massBackgroundMeta-analysesPotassium channel tetramerization domainActivity volumeRegulator 1Protein 1MET valuesRelated phenotypesPleiotropic effectsGenome-wide association studiesMetabolic energy equivalentsAssociation studiesThe blood pressure response to acute and chronic aerobic exercise: A meta-analysis of candidate gene association studies
Bruneau ML, Johnson BT, Huedo-Medina TB, Larson KA, Ash GI, Pescatello LS. The blood pressure response to acute and chronic aerobic exercise: A meta-analysis of candidate gene association studies. Journal Of Science And Medicine In Sport 2015, 19: 424-431. PMID: 26122461, DOI: 10.1016/j.jsams.2015.05.009.Peer-Reviewed Original ResearchConceptsAngiotensinogen M235TChronic aerobic exerciseDiastolic blood pressureBlood pressure changesBlood pressurePost-exercise phaseAerobic exerciseM235TAmbulatory conditionsCandidate gene association studiesBlood pressure responseAerobic exercise interventionAerobic exercise trainingGene association studiesChanges of BPMaximum oxygen consumptionOnly genetic variantExercise interventionOverweight menExercise trainingAcute exercisePressure changesSample characteristicsSystematic searchAssociation studies
2013
The promises and challenges of the use of genomics in the prescription of exercise for hypertension: the 2013 update.
Ash GI, Eicher JD, Pescatello LS. The promises and challenges of the use of genomics in the prescription of exercise for hypertension: the 2013 update. Current Hypertension Reviews 2013, 9: 130-47. PMID: 23971695, DOI: 10.2174/15734021113099990010.Peer-Reviewed Original ResearchConceptsBP responseCardiovascular disease risk factorsMajor global public health problemGlobal public health problemControl of hypertensionDisease risk factorsEffectiveness of exercisePrescription of exercisePublic health problemExercise prescriptionRisk factorsHypertensionTherapeutic modalitiesAmerican CollegeConsiderable individual variabilityHealth problemsSports medicineAerobic activityModerate intensityNext-generation sequencingAssociation studiesSpecific genetic variantsSignificant proportionMost daysGenetic variants