2024
Long‐Term Mortality Predictors Using a Machine‐Learning Approach in Patients With Chronic Limb‐Threatening Ischemia After Peripheral Vascular Intervention
Callegari S, Romain G, Cleman J, Scierka L, Jacque F, Smolderen K, Mena‐Hurtado C. Long‐Term Mortality Predictors Using a Machine‐Learning Approach in Patients With Chronic Limb‐Threatening Ischemia After Peripheral Vascular Intervention. Journal Of The American Heart Association 2024, 13: e034477. PMID: 38761075, PMCID: PMC11179837, DOI: 10.1161/jaha.124.034477.Peer-Reviewed Original ResearchConceptsChronic limb-threatening ischemiaPeripheral vascular interventionsHealth careLimb-threatening ischemiaMortality predictorsLong-term mortality riskMultidimensional risk factorsBody mass indexLong-term mortality predictorsImprove individualized careVascular interventionsIndividualized careAssisted careBiopsychosocial modelMortality riskCareMass indexRisk factorsMedical comorbiditiesRisk profileInterventionMortality rateChronic kidney diseaseMortalityPredictive variables
2023
Comparison of lower extremity bypass and peripheral vascular intervention for chronic limb-threatening ischemia in the Medicare-linked Vascular Quality Initiative
Cleman J, Romain G, Grubman S, Guzman R, Smolderen K, Mena-Hurtado C. Comparison of lower extremity bypass and peripheral vascular intervention for chronic limb-threatening ischemia in the Medicare-linked Vascular Quality Initiative. Journal Of Vascular Surgery 2023, 78: 745-753.e6. PMID: 37207790, PMCID: PMC10964324, DOI: 10.1016/j.jvs.2023.05.015.Peer-Reviewed Original ResearchConceptsChronic limb-threatening ischemiaLower extremity bypassPeripheral vascular interventionsVascular Quality InitiativeLimb-threatening ischemiaCause mortalityRisk of deathExtremity bypassVascular interventionsQuality InitiativeCox proportional hazards regressionKaplan-Meier survival curvesProportional hazards regressionOverall mean ageLogistic regression modelsComparative effectiveness researchKnee poplitealMedicare registryInfrapopliteal arteriesHazards regressionMean ageThirty-dayHispanic ethnicityOutcome dataTreatment groupsA new cure model that corrects for increased risk of non-cancer death: analysis of reliability and robustness, and application to real-life data
Botta L, Goungounga J, Capocaccia R, Romain G, Colonna M, Gatta G, Boussari O, Jooste V. A new cure model that corrects for increased risk of non-cancer death: analysis of reliability and robustness, and application to real-life data. BMC Medical Research Methodology 2023, 23: 70. PMID: 36966273, PMCID: PMC10040108, DOI: 10.1186/s12874-023-01876-x.Peer-Reviewed Original ResearchLower extremity symptoms and ankle–brachial index screening as predictors of cardiovascular outcomes in Black adults
Lee M, Smolderen K, Ionescu C, Hillegass W, Romain G, Mena-Hurtado C. Lower extremity symptoms and ankle–brachial index screening as predictors of cardiovascular outcomes in Black adults. Vascular Medicine 2023, 28: 197-204. PMID: 37293738, DOI: 10.1177/1358863x231151729.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseAbnormal ABILower extremity symptomsNormal ABILeg symptomsHigh riskBlack adultsExtremity symptomsStepwise Cox proportional hazards modelKaplan-Meier survival curvesCox proportional hazards modelAnkle-brachial indexFramingham risk factorsJackson Heart StudyProportional hazards modelCardiovascular outcomesCause mortalityArtery diseaseAsymptomatic diseaseAdverse outcomesMean ageSymptom assessmentAsymptomatic participantsRisk factorsSymptomatic participantsGuideline-Directed Medical Therapy and Long-Term Mortality and Amputation Outcomes in Patients Undergoing Peripheral Vascular Interventions
Smolderen K, Romain G, Provance J, Scierka L, Mao J, Goodney P, Henke P, Sedrakyan A, Mena-Hurtado C. Guideline-Directed Medical Therapy and Long-Term Mortality and Amputation Outcomes in Patients Undergoing Peripheral Vascular Interventions. JACC Cardiovascular Interventions 2023, 16: 332-343. PMID: 36792257, PMCID: PMC10359106, DOI: 10.1016/j.jcin.2022.09.022.Peer-Reviewed Original ResearchConceptsGuideline-directed medical therapyPeripheral vascular interventionsMedical therapyVascular interventionsEnzyme inhibitors/angiotensin receptor blockersVascular Quality Initiative registryAngiotensin receptor blockersLong-term mortalityRisk of amputationRisk of mortalityNational quality registryQuality improvement effortsAmputation outcomesAmputation riskMajor amputationAntiplatelet therapyCause mortalityReceptor blockersMean ageVascular careQuality registryObservational studyMortality riskHigh riskAmputation data
2021
Outcomes of anus squamous cell carcinoma. Management of anus squamous cell carcinoma and recurrences
Marref I, Romain G, Jooste V, Vendrely V, Lopez A, Faivre J, Gerard J, Bouvier A, Lepage C. Outcomes of anus squamous cell carcinoma. Management of anus squamous cell carcinoma and recurrences. Digestive And Liver Disease 2021, 53: 1492-1498. PMID: 34193366, DOI: 10.1016/j.dld.2021.05.028.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaCell carcinomaAnal canalNet survivalBurgundy Digestive Cancer RegistryFive-year net survivalDigestive cancer registryCumulative recurrence ratePersistent active diseaseRisk of deathMultivariate survival analysisCumulative incidence functionCurative intentActive diseaseAbdominoperineal resectionAggressive managementCancer RegistryLocal inflammationRecurrence rateChemoradiotherapyCarcinomaRecurrenceRoutine practiceSurvival analysisRadiotherapy
2020
Cancer cure for 32 cancer types: results from the EUROCARE-5 study
Dal Maso L, Panato C, Tavilla A, Guzzinati S, Serraino D, Mallone S, Botta L, Boussari O, Capocaccia R, Colonna M, Crocetti E, Dumas A, Dyba T, Franceschi S, Gatta G, Gigli A, Giusti F, Jooste V, Minicozzi P, Neamtiu L, Romain G, Zorzi M, De Angelis R, Francisci S, Group T. Cancer cure for 32 cancer types: results from the EUROCARE-5 study. International Journal Of Epidemiology 2020, 49: 1517-1525. PMID: 32984907, DOI: 10.1093/ije/dyaa128.Peer-Reviewed Original ResearchConceptsConditional relative survivalCancer patientsProstate cancerCancer cureChronic lymphocytic leukemia patientsProportion of patientsThyroid cancer patientsEUROCARE-5 studyLymphocytic leukemia patientsSame death ratePopulation-based indicatorsMelanoma patientsPatients' qualityCorpus uteriFatal casesLung cancerPancreatic cancerThyroid cancerLeukemia patientsBreast cancerGeneral populationRelative survivalPatientsSkin melanomaAge 55
2019
Net survival in recurrence-free colon cancer patients
Drouillard A, Bouvier A, Boussari O, Romain G, Manfredi S, Lepage C, Faivre J, Jooste V. Net survival in recurrence-free colon cancer patients. Cancer Epidemiology 2019, 61: 124-128. PMID: 31212224, DOI: 10.1016/j.canep.2019.06.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedColonic NeoplasmsFemaleHumansMaleMiddle AgedPrognosisQuality of LifeSurvival AnalysisSurvivorsConceptsRecurrence-free patientsNet survivalColon cancerPopulation-based digestive cancer registryConditional net survivalDigestive cancer registryStage III diseasePeriods of remissionEstimation of prognosisPrimary colon cancerColon cancer patientsRelevant clinical informationCancer RegistryClinical presentationCancer patientsCancer populationSurvivors' qualityClinical informationPatientsStage IStage IIIStage IIDiagnosisFlexible parametric modelsSurvivalTime-to-cure and cure proportion in solid cancers in France. A population based study
Romain G, Boussari O, Bossard N, Remontet L, Bouvier A, Mounier M, Iwaz J, Colonna M, Jooste V, Registries F. Time-to-cure and cure proportion in solid cancers in France. A population based study. Cancer Epidemiology 2019, 60: 93-101. PMID: 30933890, DOI: 10.1016/j.canep.2019.02.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDatabases, FactualFemaleFranceHumansMaleMiddle AgedNeoplasmsRegistriesSurvival RateConceptsTestis cancerCancer sitesThyroid cancerCure proportionFrench cancer registriesMost cancer sitesLarge national databaseHealthcare policy makersGynaecologic cancerYounger patientsCancer RegistryColorectal cancerSurvival cure modelUrinary tractCancer careDigestive cancersSolid cancersSkin melanomaSolid tumorsSmall intestineCancerPatientsNational databaseBreastCure
2018
Time trends and short term projections of cancer prevalence in France
Colonna M, Boussari O, Cowppli-Bony A, Delafosse P, Romain G, Grosclaude P, Jooste V, Registries F. Time trends and short term projections of cancer prevalence in France. Cancer Epidemiology 2018, 56: 97-105. PMID: 30125884, DOI: 10.1016/j.canep.2018.08.001.Peer-Reviewed Original ResearchA new approach to estimate time-to-cure from cancer registries data
Boussari O, Romain G, Remontet L, Bossard N, Mounier M, Bouvier A, Binquet C, Colonna M, Jooste V. A new approach to estimate time-to-cure from cancer registries data. Cancer Epidemiology 2018, 53: 72-80. PMID: 29414635, DOI: 10.1016/j.canep.2018.01.013.Peer-Reviewed Original ResearchConceptsPopulation-based cancer dataFlexible parametric cure modelsThyroid cancer patientsCancer registry dataParametric cure modelsCancer RegistryColorectal cancerCancer patientsPancreatic cancerCancer sitesBreast cancerRegistry dataCure modelAge groupsCancerCureDiagnosisSurvival frameworkCure fractionPatientsHealth insurance premiumsFrench networkSurvival time distributionYears
2017
Outcomes following polypectomy for malignant colorectal polyps are similar to those following surgery in the general population
Lopez A, Bouvier A, Jooste V, Cottet V, Romain G, Faivre J, Manfredi S, Lepage C. Outcomes following polypectomy for malignant colorectal polyps are similar to those following surgery in the general population. Gut 2017, 68: 111. PMID: 29074726, DOI: 10.1136/gutjnl-2016-312093.Peer-Reviewed Original ResearchConceptsSessile malignant polypsColorectal malignant polypsMalignant polypsPathological marginsEndoscopic resectionSurgical resectionRecurrence rateGeneral populationAge-standardised incidence ratesFive-year net survivalAge-standardised incidenceCumulative recurrence ratePopulation-based studyMalignant colorectal polypsTransanal resectionIncidence rateResectionColorectal polypsNet survivalPatientsSurvival analysisSurgeryPolypectomyTime trendsOutcomes