Accumulation of methylsulfonylmethane in the human brain: identification by multinuclear magnetic resonance spectroscopy
Lin A, Nguy C, Shic F, Ross B. Accumulation of methylsulfonylmethane in the human brain: identification by multinuclear magnetic resonance spectroscopy. Toxicology Letters 2001, 123: 169-177. PMID: 11641045, DOI: 10.1016/s0378-4274(01)00396-4.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdultAgedAspartic AcidBrainBrain ChemistryCholineCreatineDimethyl SulfoxideFemaleHumansInositolMaleMemory DisordersMiddle AgedNuclear Magnetic Resonance, BiomolecularSulfonesTime FactorsConceptsIntact blood-brain barrierBlood-brain barrierProbable Alzheimer's diseaseMagnetic resonance spectroscopyHuman brainVivo magnetic resonance spectroscopyNeurochemical effectsNormal subjectsNormal volunteersWhite matterAlzheimer's diseaseMethylsulfonylmethaneMemory lossPatientsToxic exposureBrainMedical benefitsResonance spectroscopySubjectsDiseaseDiagnosisDosesDailyVolunteers