2022
Health-related quality of life in people receiving opioid agonist treatment and treatment for hepatitis C virus infection
Dalgard O, Litwin AH, Shibolet O, Grebely J, Nahass R, Altice FL, Conway B, Gane EJ, Luetkemeyer AF, Peng CY, Iser D, Gendrano IN, Kelly MM, Haber BA, Platt H, Puenpatom A. Health-related quality of life in people receiving opioid agonist treatment and treatment for hepatitis C virus infection. Journal Of Addictive Diseases 2022, 41: 213-224. PMID: 35920743, DOI: 10.1080/10550887.2022.2088978.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmidesAnalgesics, OpioidAntiviral AgentsHepacivirusHepatitis C, ChronicHumansQuality of LifeConceptsElbasvir/grazoprevirHepatitis C virus infectionC virus infectionOpioid agonist therapyHealth-related qualityEnd of treatmentHCV infectionAgonist therapyVirus infectionChronic hepatitis C virus (HCV) infectionImproved health-related qualityMental component summary scoresTreatment week 4Placebo-controlled studyOpioid agonist treatmentMedical Outcomes StudyComponent summary scoresSF-36v2 scoresTreatment differencesImproved HRQOLViral eradicationActing antiviralsOpioid dependenceAgonist treatmentGeneral health
2019
Treating opioid dependence with extended-release naltrexone (XR-NTX) in Ukraine: Feasibility and three-month outcomes
Makarenko I, Pykalo I, Springer SA, Mazhnaya A, Marcus R, Filippovich S, Dvoriak S, Altice FL. Treating opioid dependence with extended-release naltrexone (XR-NTX) in Ukraine: Feasibility and three-month outcomes. Journal Of Substance Use And Addiction Treatment 2019, 104: 34-41. PMID: 31370983, PMCID: PMC8215516, DOI: 10.1016/j.jsat.2019.05.008.Peer-Reviewed Original ResearchConceptsOpioid use disorderOpioid agonist treatmentXR-NTX injectionXR-NTX treatmentXR-NTXUrine drug testingOpioid useExtended-release naltrexoneMonths of treatmentThree-month outcomeHealth-related qualityAdverse side effectsSymptoms of depressionOpioid dependenceAgonist treatmentLife scoresTreatment optionsIndependent factorsSide effectsUse disordersPeriod of observationDrug useStimulant useTreatment motivationDrug testing
2017
Cohort profile: seek, test, treat and retain United States criminal justice cohort
Chandler R, Gordon MS, Kruszka B, Strand LN, Altice FL, Beckwith CG, Biggs ML, Cunningham W, Chris Delaney JA, Flynn PM, Golin CE, Knight K, Kral AH, Kuo I, Lorvick J, Nance RM, Ouellet LJ, Rich JD, Sacks S, Seal D, Spaulding A, Springer SA, Taxman F, Wohl D, Young JD, Young R, Crane HM. Cohort profile: seek, test, treat and retain United States criminal justice cohort. Substance Abuse Treatment, Prevention, And Policy 2017, 12: 24. PMID: 28511680, PMCID: PMC5433052, DOI: 10.1186/s13011-017-0107-4.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsTreatment cascadeViral loadHIV RNA viral loadCD4 T-cell countRisk behaviorsSubstance useT-cell countsHepatitis C infectionRNA viral loadInjection drug useHealth Related QualityHIV treatment cascadeUnprotected sexual intercourseHealth care accessRecent polysubstance useC infectionViral suppressionHIV diagnosisHIV infectionMedian ageRelated qualityCriminal justice involvementART treatmentCohort membersPrimary healthcare-based integrated care with opioid agonist treatment: First experience from Ukraine
Morozova O, Dvoriak S, Pykalo I, Altice FL. Primary healthcare-based integrated care with opioid agonist treatment: First experience from Ukraine. Drug And Alcohol Dependence 2017, 173: 132-138. PMID: 28242537, PMCID: PMC5545131, DOI: 10.1016/j.drugalcdep.2016.12.025.Peer-Reviewed Original ResearchMeSH KeywordsAdultBuprenorphineCross-Sectional StudiesDelivery of Health Care, IntegratedFemaleHealth Services ResearchHIV InfectionsHumansMaleMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient DropoutsPatient SatisfactionPilot ProjectsPrimary Health CareQuality of LifeSubstance Abuse, IntravenousUkraineConceptsOpioid agonist therapyPrimary healthcare clinicsIntegrated carePHC staffHIV patientsHIV epidemicOAT patientsOpioid agonist treatmentStandard of careAddiction treatment settingsAgonist therapyObservational cohortMiddle-income countriesAgonist treatmentPrimary careComprehensive healthcare servicesPWIDHealthcare clinicsAddiction clinicPatientsTreatment settingsDrug usersPilot studyCareHealthcare servicesA Moderated Mediation Model of HIV-Related Stigma, Depression, and Social Support on Health-Related Quality of Life among Incarcerated Malaysian Men with HIV and Opioid Dependence
Shrestha R, Copenhaver M, Bazazi AR, Huedo-Medina TB, Krishnan A, Altice FL. A Moderated Mediation Model of HIV-Related Stigma, Depression, and Social Support on Health-Related Quality of Life among Incarcerated Malaysian Men with HIV and Opioid Dependence. AIDS And Behavior 2017, 21: 1059-1069. PMID: 28108877, PMCID: PMC5344717, DOI: 10.1007/s10461-017-1693-x.Peer-Reviewed Original Research
2016
The Influence of Neurocognitive Impairment, Depression, and Alcohol Use Disorders on Health-Related Quality of Life among Incarcerated, HIV-Infected, Opioid Dependent Malaysian Men: A Moderated Mediation Analysis
Shrestha R, Weikum D, Copenhaver M, Altice FL. The Influence of Neurocognitive Impairment, Depression, and Alcohol Use Disorders on Health-Related Quality of Life among Incarcerated, HIV-Infected, Opioid Dependent Malaysian Men: A Moderated Mediation Analysis. AIDS And Behavior 2016, 21: 1070-1081. PMID: 27544515, PMCID: PMC5318281, DOI: 10.1007/s10461-016-1526-3.Peer-Reviewed Original ResearchConceptsAlcohol use disorderNeurocognitive impairmentUse disordersMalaysia's largest prisonHealth-related qualityNeuropsychological factorsQuality of lifeLargest prisonHIV-InfectedOpioid dependenceHIV treatmentHRQoLImportant negative predictorMeeting criteriaFuture interventionsDepressionNegative predictorPLWHDisordersMalaysian menStandardized scalesImpairmentMediation analysisHRQoL.HIV
2013
Integration of health services improves multiple healthcare outcomes among HIV-infected people who inject drugs in Ukraine
Bachireddy C, Soule MC, Izenberg JM, Dvoryak S, Dumchev K, Altice FL. Integration of health services improves multiple healthcare outcomes among HIV-infected people who inject drugs in Ukraine. Drug And Alcohol Dependence 2013, 134: 106-114. PMID: 24128379, PMCID: PMC3865106, DOI: 10.1016/j.drugalcdep.2013.09.020.Peer-Reviewed Original ResearchConceptsOpioid substitution therapyOpioid-dependent PWIDIsoniazid preventive therapyHealth-related qualityNeedles/syringesHIV-endemic regionsComposite scoreCross-sectional studyHealthcare quality indicatorsAntiretroviral therapyTuberculosis servicesPreventive therapySecondary outcomesHigher HRQoLMiddle-income countriesPrimary outcomePoor outcomeSubstitution therapyPotential confoundersTuberculosis treatmentHIV epidemicHIVHealth servicesPWIDOutreach settings
2011
Improved Quality of Life for Opioid-Dependent Patients Receiving Buprenorphine Treatment in HIV Clinics
Korthuis PT, Tozzi MJ, Nandi V, Fiellin DA, Weiss L, Egan JE, Botsko M, Acosta A, Gourevitch MN, Hersh D, Hsu J, Boverman J, Altice FL. Improved Quality of Life for Opioid-Dependent Patients Receiving Buprenorphine Treatment in HIV Clinics. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2011, 56: s39-s45. PMID: 21317593, PMCID: PMC3073082, DOI: 10.1097/qai.0b013e318209754c.Peer-Reviewed Original ResearchConceptsSF-12 scoresGeneral US populationOpioid dependenceUS populationPoor health-related qualityShort Form Health SurveyBUP/NXBuprenorphine/naloxoneHIV care settingsOpioid-dependent patientsOpioid-dependent personsForm Health SurveyHealth-related qualityQuality of lifeBup/Mean HRQoLHIV clinicMaintenance therapyBuprenorphine treatmentHIV infectionPhysical HRQoLMental HRQOLHRQoL domainsMixed effects regressionHealth Survey